{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:44:57Z","timestamp":1777412697220,"version":"3.51.4"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Catheter ablation (CA) plays a central role in the management of electrical storm (ES). PAINESD and iVT are two validated scores commonly used to assess periprocedural risk in patients undergoing ventricular tachycardia (VT) ablation. This study aimed to evaluate the association between CA and mortality in ES patients stratified by PAINESD and iVT risk scores.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We included 606 patients admitted for ES across four French centres. Risk was assessed using PAINESD and iVT scores. Mortality at 1 year was compared according to risk group and CA status. Baseline differences were adjusted using inverse probability of treatment weighting (IPTW) based on predefined clinical variables. Forty-one per cent of patients were classified as high-risk using the PAINESD score, and 39.4% using the iVT score. Catheter ablation was performed in 42.4% of the cohort, including 39.4% of hi-PAINESD and 35.5% of hi-iVT patients. After adjustment, CA was associated with lower 1-year mortality in both high- and low-risk groups (adjusted HR: 0.42 [95% CI: 0.26\u20130.66], P = 0.0002 for hi-PAINESD; 0.31 [0.18\u20130.53], P &amp;lt; 0.0001 for hi-iVT). Inverse probability of treatment weighting-weighted models yielded consistent results. In exploratory interaction analyses, the iVT score\u2014but not PAINESD\u2014identified high-risk patients who may derive earlier survival benefit from VT ablation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In patients with electrical storm, VT ablation was associated with lower 1-year mortality across both low- and high-risk profiles. The iVT score may help identify high-risk patients who derive earlier benefit from ablation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euaf188","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T09:01:54Z","timestamp":1755680514000},"source":"Crossref","is-referenced-by-count":5,"title":["Impact of ventricular tachycardia ablation in the setting of electrical storm based on patient risk profile"],"prefix":"10.1093","volume":"27","author":[{"given":"Sandro","family":"Ninni","sequence":"first","affiliation":[{"name":"Department of Cardiology, Lille University Hospital , 59000 Lille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3554-7714","authenticated-orcid":false,"given":"Charles","family":"Guenancia","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dijon University Hospital , Dijon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oph\u00e9lie","family":"Bourdrel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Lille University Hospital , 59000 Lille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2133-5620","authenticated-orcid":false,"given":"Rayan","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Saint-Etienne University Hospital , Saint-Etienne ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0558-6833","authenticated-orcid":false,"given":"Donovan","family":"Decaudin","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Rennes University Hospital , Rennes ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9dric","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Lille University Hospital , 59000 Lille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Salaun","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dijon University Hospital , Dijon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2244-9779","authenticated-orcid":false,"given":"Ruxandra","family":"Sava","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Saint-Etienne University Hospital , Saint-Etienne ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amine","family":"Tazibet","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Lille University Hospital , 59000 Lille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7375-8506","authenticated-orcid":false,"given":"Soundous","family":"M'Rabet","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dijon University Hospital , Dijon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7019-9727","authenticated-orcid":false,"given":"Pierre Gr\u00e9goire","family":"Guinot","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dijon University Hospital , Dijon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8832-9157","authenticated-orcid":false,"given":"Pierre","family":"Groussin","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Rennes University Hospital , Rennes ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3302-9988","authenticated-orcid":false,"given":"Antoine","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Saint-Etienne University Hospital , Saint-Etienne ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Pavin","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Rennes University Hospital , Rennes ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4548-876X","authenticated-orcid":false,"given":"Didier","family":"Klug","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Lille University Hospital , 59000 Lille ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5716-6712","authenticated-orcid":false,"given":"Rapha\u00ebl","family":"Martins","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Rennes University Hospital , Rennes ,","place":["France"]},{"name":"INSERM-LTSI , Rennes U1099 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7108-3427","authenticated-orcid":false,"given":"Karim","family":"Benali","sequence":"additional","affiliation":[{"name":"Section of Cardiac Electrophysiology, Saint-Etienne University Hospital , Saint-Etienne ,","place":["France"]},{"name":"IHU Liryc, Electrophysiology and Heart Modeling Institute , Bordeaux ,","place":["France"]},{"name":"Haut-Leveque University Hospital , Bordeaux ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"2025091919535079100_euaf188-B1","doi-asserted-by":"crossref","first-page":"euae049","DOI":"10.1093\/europace\/euae049","article-title":"Management of patients with an electrical storm or clustered ventricular arrhythmias: a clinical consensus statement of the European Heart Rhythm Association of the ESC\u2014endorsed by the Asia-Pacific Heart Rhythm Society, Heart Rhythm Society, and Latin-American Heart Rhythm Society","volume":"26","author":"Lenarczyk","year":"2024","journal-title":"Europace"},{"key":"2025091919535079100_euaf188-B2","first-page":"zuac044","article-title":"Incidence and predictors of mortality after an electrical storm in the ICU","volume":"11","author":"Ninni","year":"2022","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2025091919535079100_euaf188-B3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa1513614","article-title":"Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs","volume":"375","author":"Sapp","year":"2016","journal-title":"N Engl J Med"},{"key":"2025091919535079100_euaf188-B4","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/CIRCEP.114.002155","article-title":"Acute hemodynamic decompensation during catheter ablation of scar-related ventricular tachycardia: incidence, predictors, and impact on mortality","volume":"8","author":"Santangeli","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2025091919535079100_euaf188-B5","doi-asserted-by":"crossref","first-page":"e006730","DOI":"10.1161\/CIRCEP.118.006730","article-title":"A predictive score for identifying survival and recurrence risk profiles in patients undergoing ventricular tachycardia ablation: the I-VT 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ventricular arrhythmias","volume":"21","author":"Cronin","year":"2019","journal-title":"Europace"},{"key":"2025091919535079100_euaf188-B9","first-page":"e73","article-title":"2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"15","author":"Al-Khatib","year":"2018","journal-title":"Circulation"},{"key":"2025091919535079100_euaf188-B10","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1161\/01.CIR.103.16.2066","article-title":"Electrical storm presages nonsudden death: the antiarrhythmics versus implantable defibrillators (AVID)","volume":"103","author":"Exner","year":"2001","journal-title":"Trial. 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