{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:25:40Z","timestamp":1792193140168,"version":"4.4.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Catheter ablation for premature ventricular contractions (PVCs) triggering ventricular fibrillation (VF) after acute myocardial infarction (AMI) has proven effective, with Purkinje potentials often serving as the target. However, the electrophysiological features of Purkinje potentials and their relationship with the conduction system in VF-triggering PVCs remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicentre retrospective study analysed patients who underwent catheter ablation for VF-triggering PVCs during the acute or subacute phase of AMI. Characteristics of Purkinje potentials, including retrograde conduction from the Purkinje network and subsequent anterograde conduction to the right bundle branch (RB), were evaluated for PVC morphology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty-three patients (mean age 66\u00b111 years; 13% female) with 67 VF-triggering PVCs were analysed. The mean PVC width was 157 \u00b1 42\u2005ms, with 87% showing RB branch block morphology. Purkinje potentials preceded 72% of PVCs (mean interval 68 \u00b1 42\u2005ms). PVCs with preceding Purkinje potentials had narrower QRS duration (145 \u00b1 26\u2005ms vs. 198 \u00b1 57\u2005ms, P &amp;lt; 0.0001). The coupling interval from the preceding sinus beat was inversely correlated with the interval from Purkinje potential to PVC onset (P &amp;lt; 0.0001). Retrograde Purkinje conduction with subsequent anterograde RB conduction was identified in 9%. In these cases, the coupling interval from the preceding sinus beat was longer (391 \u00b1 12\u2005ms vs. 467 \u00b1 34\u2005ms, P = 0.041).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Purkinje potentials show distinct properties that influence both QRS duration and PVC timing. The presence of preceding Purkinje potentials together with QRS duration may help guide ablation strategies. In rare cases, Purkinje activity conducts retrogradely from the left bundle and anterogradely through the RB, modifying PVC morphology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euaf249","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T13:16:46Z","timestamp":1764854206000},"source":"Crossref","is-referenced-by-count":4,"title":["Electrophysiological characteristics of Purkinje potentials and the conduction system in premature ventricular contractions triggering ventricular fibrillation after myocardial infarction"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8927-0730","authenticated-orcid":false,"given":"Tatsuya","family":"Hayashi","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University , 1-847 Amanuma-cho, Omiya-ku, Saitama-si, Saitama 330-0834 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Kitakyushu ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8193-6617","authenticated-orcid":false,"given":"Akira","family":"Mizukami","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kameda Medical Center , Chiba ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Inaba","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Japanese Red Cross Society Saitama Hospital , Saitama ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6364-5725","authenticated-orcid":false,"given":"Yuhei","family":"Kasai","sequence":"additional","affiliation":[{"name":"Asia Medical Group, Department of Cardiology, Sapporo CardioVascular Clinic, Sapporo Heart Center , Sapporo 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