{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:32:55Z","timestamp":1790415175822,"version":"4.1.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016242","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016242","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The long-term impact of left atrial appendage occlusion (LAAO) plus ablation for atrial fibrillation remains controversial. The present study aims to compare the three-year clinical outcomes of LAAO patients with or without one-staged ablation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>The RECORD study (NCT03917563) was a prospective registry conducted in 39 participating sites in China between 1 April 2019 and 31 October 2020, which consecutively enrolled 3082 patients who successfully received the WATCHMAN LAAO device. The current study compared patients who received LAAO only to patients who underwent LAAO plus ablation. A 1:1 propensity score matching was performed to attenuate confounding. The primary outcome was a composite endpoint of cardiovascular death, stroke, and systemic embolism at 3-year. 1633\/2928 (55.8%) patients received LAAO only and 1295\/2928 (44.2%) received LAAO plus ablation. After propensity score matching, 1016\/2032 (50.0%) were in the LAAO group and 1016\/2032 (50.0%) in the LAAO plus ablation group. The mean \u00b1 SD age was 68.8 \u00b1 9.3 years, with 815 (40.1%) participants being female. The mean \u00b1 SD CHA2DS2-VASc and HAS-BLED scores at baseline were 3.9 \u00b1 1.8 and 2.4 \u00b1 1.1, respectively. At three-year, compared to LAAO only, LAAO plus ablation was associated with a lower risk of cardiovascular death, stroke, systemic embolism (6.9%vs.10.4%, HRPSM:0.66, 95%CI: 0.49\u20130.89, P = 0.007), which was driven mainly by the lower risk of cardiovascular death (3.7% vs. 7.3%, HRPSM: 0.50, 95%CI: 0.34\u20130.74, P = 0.001). No significant between-group differences were noted for BARC-defined bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LAAO plus ablation was associated with a lower risk of a composite of cardiovascular death, stroke, and systemic embolism than LAAO only at 3-year. However, given the observational nature of the current study, the results should be considered as hypothesis-generating only.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euag022","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T12:50:32Z","timestamp":1770209432000},"source":"Crossref","is-referenced-by-count":4,"title":["Three-year clinical outcomes of left atrial appendage occlusion with or without ablation: insight from the RECORD study"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8636-0266","authenticated-orcid":false,"given":"Tingting","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueni","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2439-568X","authenticated-orcid":false,"given":"Guotao","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China , Lujiang road, Hefei 230001 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4419-2477","authenticated-orcid":false,"given":"Jianzheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7695-7341","authenticated-orcid":false,"given":"Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengquan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Xijing Hospital, The Fourth Military Medical University , Changle west road, Xi'an 710032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4431-1217","authenticated-orcid":false,"given":"Xianxian","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Changhai Hospital, Navy Military Medical University , Shanghai ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2791-6831","authenticated-orcid":false,"given":"Huimin","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Arrhythmia Center, Ningbo First Hospital , Ningbo ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0607-0010","authenticated-orcid":false,"given":"Zhongbao","family":"Ruan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Taizhou People's Hospital , Taizhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8402-6907","authenticated-orcid":false,"given":"Xiaofei","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital) , Zhuhai ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengxing","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6094-8387","authenticated-orcid":false,"given":"Yansong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Provincial Hospital Affiliated to Fuzhou University , Fuzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, General Hospital of Northern Theater Command , Shenyang ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Hospital of Lanzhou University , Lanzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqiang","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Seventh People's Hospital of Zhengzhou , Zhengzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9905-7899","authenticated-orcid":false,"given":"Haixiong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Shanxi Cardiovascular Hospital , Taiyuan ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-3353","authenticated-orcid":false,"given":"Chenyang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sir Run Shaw Hospital, Zhejiang University School of Medicine , Hangzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0896-486X","authenticated-orcid":false,"given":"Shijun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dalian Municipal Central Hospital , Dalian ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8911-0278","authenticated-orcid":false,"given":"Scot","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Royal Blackburn Hospital , Blackburn 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