{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T11:43:13Z","timestamp":1785930193425,"version":"3.56.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aim of this analysis was to evaluate the upgradeability of a single-chamber leadless pacemaker (LP) to a dual-chamber system in patients indicated for a dual-chamber pacemaker.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A prospective, multicentre study evaluated the safety and performance of a dual-chamber LP. The study included patients with a prior ventricular LP to evaluate its upgradeability. Patients had an attempted atrial LP implant, and if successfully implanted, the LPs were paired to a dual-chamber pacing mode to evaluate upgrade success. Patients were followed for 12 months from the attempted atrial LP implantation. Among 35 patients with an attempted upgrade (62.9% male, average age 70 years), the most common primary indication was sinus node dysfunction (57.1%). Out of 35 patients, 91.4% had successful upgrades. The mean atrial device electrical measurements stabilized within 1 month from the procedure and remained stable through 12 months (capture threshold at 0.4\u2005ms 0.8 \u00b1 0.6\u2005V, sense amplitude 4.5 \u00b1 2.7\u2005mV at 12 months). A total of five (14.3%) patients experienced seven complications, all of which were procedure-related. There were no device or procedure-related deaths. The total estimated battery longevity (accounting for time since implant) evaluated at 12 months was 11.3 \u00b1 4.2 and 5.7 \u00b1 2.6 years for the ventricular and atrial LPs, respectively. One patient required an atrial LP revision 10 months after implantation. The LP was retrieved and replaced.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These data confirm the feasibility, safety, and long-term effectiveness of adding an atrial LP in patients with a pre-existing ventricular LP to achieve dual-chamber leadless pacing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euag023","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:32:35Z","timestamp":1771331555000},"source":"Crossref","is-referenced-by-count":1,"title":["Upgrading expandable leadless pacemakers from single- to dual-chamber"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4755-1064","authenticated-orcid":false,"given":"Maria Grazia","family":"Bongiorni","sequence":"first","affiliation":[{"name":"Interventional Arrhythmology Unit, San Rossore Private Hospital and Medical Center , Pisa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5555-7672","authenticated-orcid":false,"given":"Rahul","family":"Doshi","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Group , HonorHealth, Scottsdale, AZ ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3461-505X","authenticated-orcid":false,"given":"James E","family":"Ip","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Weill Cornell Medicine\/New York Presbyterian Hospital , New York, NY ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek V","family":"Exner","sequence":"additional","affiliation":[{"name":"Cardiac Implantable Electrical Device Clinic, Foothills Medical Centre , Calgary ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-4993","authenticated-orcid":false,"given":"Vivek Y","family":"Reddy","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology, Mount Sinai Fuster Heart Hospital , New York, NY ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7183-4278","authenticated-orcid":false,"given":"Pascal","family":"Defaye","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, CHRU Albert Michallon , Grenoble ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5741-7100","authenticated-orcid":false,"given":"Robert","family":"Canby","sequence":"additional","affiliation":[{"name":"Clinical Cardiac Electrophysiology, Texas Cardiac Arrhythmia Institute , Austin, TX ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1772-6823","authenticated-orcid":false,"given":"Morio","family":"Shoda","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tokyo Women\u2019s Medical University , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-0773","authenticated-orcid":false,"given":"Gerhard","family":"Hindricks","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum der Charit\u00e9, Department of Cardiology, Angiology and Intensive Care Medicine , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4317-978X","authenticated-orcid":false,"given":"Mayer","family":"Rashtian","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology, Huntington Hospital , Pasadena, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4334-8165","authenticated-orcid":false,"given":"Petr","family":"Neuzil","sequence":"additional","affiliation":[{"name":"Department of Cardiac Arrhythmia Service, Na Homolce Hospital , Prague ,","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2695-7130","authenticated-orcid":false,"given":"Rajesh","family":"Banker","sequence":"additional","affiliation":[{"name":"Hoag Medical Group, Premier Cardiology, Inc. , Newport Beach, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1693-496X","authenticated-orcid":false,"given":"Stephanie M","family":"Delgado","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management, Abbott , Sylmar, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8631-5656","authenticated-orcid":false,"given":"Leonard","family":"Ganz","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management, Abbott , Sylmar, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5588-9811","authenticated-orcid":false,"given":"Chris","family":"Hubbard","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management, Abbott , Sylmar, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuradha","family":"Bulusu","sequence":"additional","affiliation":[{"name":"Cardiac Rhythm Management, Abbott , Sylmar, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0772-3573","authenticated-orcid":false,"given":"Reinoud 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delivered by a dual-chamber leadless pacemaker system","volume":"150","author":"Ip","year":"2024","journal-title":"Circulation"},{"key":"2026022404233772500_euag023-B7","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.hrthm.2024.10.020","article-title":"Chronic wireless communication between dual-chamber leadless pacemaker devices","volume":"22","author":"Doshi","year":"2025","journal-title":"Heart Rhythm"},{"key":"2026022404233772500_euag023-B8","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1016\/j.hrthm.2025.03.1941","article-title":"Dual-chamber leadless pacemaker implant procedure outcomes: insights from the AVEIR DR i2i study","volume":"22","author":"Doshi","year":"2025","journal-title":"Heart Rhythm"},{"key":"2026022404233772500_euag023-B9","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1016\/j.hrthm.2024.04.091","article-title":"Six-month electrical performance of the first dual-chamber leadless 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