{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:14:05Z","timestamp":1784751245010,"version":"3.55.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001677","name":"French Institute of Health and Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003100","name":"French Federation of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003100","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005630","name":"French Society of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016242","name":"Boston Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016242","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Subcutaneous implantable cardioverter defibrillator (S-ICD) therapy is a well-established therapy for the prevention of sudden cardiac death. Although general anaesthesia (GA) was initially advocated for implantation, non-GA has emerged as a feasible alternative in clinical practice. This study evaluated the early and long-term outcomes associated with anaesthetic modality during S-ICD implantation procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>The nationwide, single-arm, observational HONEST cohort study included all patients implanted with an S-ICD (EMBLEM\u2122, Boston Scientific) in France between 2012 and 2019. GA was characterised by controlled unconsciousness with airway management, while non-GA included all alternative techniques. Among 4924 patients, 1041 (21.1%) underwent non-GA. The proportion of non-GA use increased from 2.5% to 26.9% between 2012 and 2019 (P &amp;lt; 0.001). Patients undergoing implantation under non-GA tended to be older (51 \u00b1 14 vs. 50 \u00b1 15 years), had lower left ventricular ejection fraction (41 \u00b1 16 vs. 43 \u00b1 17%), and fewer secondary prevention indications (33 vs. 38%) (all P &amp;lt; 0.01). The 30-day complication rate was 3.4% in the non-GA group (vs. 3.7% in the GA group; P = 0.85). At follow-up, the incidence of overall complications (4.29 events per 100 person-years for non-GA vs. 4.73 for GA; P = 0.937), reintervention (1.21 vs. 1.62; P = 0.963), inappropriate shocks (2.88 vs. 2.78; P = 0.782), and all-cause mortality (2.93 vs. 2.56; P = 0.938) were similar between groups. Multivariable analysis confirmed that there were no differences across outcomes (all P values &amp;gt;0.1).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The anaesthesia strategy used for S-ICD implantation was not associated with poorer short- or long-term clinical outcomes, supporting non-general anaesthesia as a feasible alternative in appropriately selected patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>ClinicalTrials.gov ID<\/jats:title>\n                    <jats:p>NCT05302115<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euag148","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T11:48:36Z","timestamp":1781092116000},"source":"Crossref","is-referenced-by-count":0,"title":["Early complications and long-term outcomes of patients treated with a subcutaneous cardioverter-defibrillator: temporal trends and clinical implications of the anaesthetic strategies adopted at implant"],"prefix":"10.1093","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7233-5901","authenticated-orcid":false,"given":"Luca","family":"Donisi","sequence":"first","affiliation":[{"name":"Division of Cardiology, European Georges Pompidou Hospital , Paris ,","place":["France"]},{"name":"Universit\u00e9 Paris Cit\u00e9, PARCC, INSERM U970 , Paris ,","place":["France"]},{"name":"Department of Clinical Sciences and Community Health, University of Milan , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7857-3576","authenticated-orcid":false,"given":"Fawzi","family":"Kerkouri","sequence":"additional","affiliation":[{"name":"Division of Cardiology, European Georges Pompidou Hospital , Paris ,","place":["France"]},{"name":"Universit\u00e9 Paris Cit\u00e9, PARCC, INSERM U970 , Paris ,","place":["France"]},{"name":"Univ Brest, Laboratoire ORPHY EA 4324 , Brest F-29200 ,","place":["France"]},{"name":"Department of Cardiology, University Hospital of Brest , Brest ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8242-3551","authenticated-orcid":false,"given":"Christelle","family":"Marqui\u00e9","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Lille , Lille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5492-8619","authenticated-orcid":false,"given":"Vincent","family":"Probst","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nantes , Nantes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5971-1235","authenticated-orcid":false,"given":"Vincent","family":"Algalarrondo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bichat Hospital , Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Al Amoura","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier de Troyes , Troyes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4199-4019","authenticated-orcid":false,"given":"Marc","family":"Badoz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Besancon , Besancon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Bastard","sequence":"additional","affiliation":[{"name":"Department of 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