{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T16:38:01Z","timestamp":1786379881027,"version":"build-2736575974"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1093\/europace\/eut049","type":"journal-article","created":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T03:46:04Z","timestamp":1362627964000},"page":"1499-1506","source":"Crossref","is-referenced-by-count":77,"title":["True complete left bundle branch block morphology strongly predicts good response to cardiac resynchronization therapy"],"prefix":"10.1093","volume":"15","author":[{"given":"Yun","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiangang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuizhen","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,3,6]]},"reference":[{"key":"key\n\t\t\t\t20170624061732_EUT049C1","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1056\/NEJMoa032423","article-title":"Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure","volume":"350","author":"Bristow","year":"2004","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170624061732_EUT049C2","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJMoa050496","article-title":"The effect of cardiac resynchronization on morbidity and mortality in heart failure","volume":"352","author":"Cleland","year":"2005","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170624061732_EUT049C3","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1056\/NEJMoa1009540","article-title":"Cardiac-resynchronization therapy for mild-to-moderate heart failure","volume":"363","author":"Tang","year":"2010","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170624061732_EUT049C4","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1161\/CIRCULATIONAHA.110.960898","article-title":"Effectiveness of cardiac resynchronization therapy by QRS morphology in the Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT)","volume":"123","author":"Zareba","year":"2011","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170624061732_EUT049C5","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1161\/CIRCEP.111.962605","article-title":"Paced left ventricular QRS width and ECG parameters predict outcomes after cardiac resynchronization therapy: PROSPECT-ECG substudy","volume":"4","author":"Hsing","year":"2011","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C6","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1093\/eurheartj\/ehs104","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"33","author":"McMurray","year":"2012","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170624061732_EUT049C7","doi-asserted-by":"crossref","first-page":"e283","DOI":"10.1161\/CIR.0b013e318276ce9b","article-title":"2012 ACCF\/AHA\/HRS focused update of the 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"127","author":"Tracy","year":"2013","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170624061732_EUT049C8","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1161\/01.CIR.0000085656.57918.B1","article-title":"Resynchronization therapy for the treatment of heart failure","volume":"108","author":"Saxon","year":"2003","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170624061732_EUT049C9","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1016\/j.jacc.2004.08.016","article-title":"Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy","volume":"44","author":"Bax","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2004.02.055","article-title":"Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal","volume":"44","author":"Bax","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C11","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S0735-1097(85)80335-1","article-title":"Criteria for intraventricular conduction disturbances and pre-excitation. World Health Organizational\/International Society and Federation for Cardiology Task Force Ad Hoc","volume":"5","author":"Willems","year":"1985","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C12","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2008.12.013","article-title":"AHA\/ACCF\/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology","volume":"53","author":"Surawicz","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C13","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/j.1540-8159.2010.03022.x","article-title":"The QRS narrowing index predicts reverse left ventricular remodeling following cardiac resynchronization therapy","volume":"34","author":"Rickard","year":"2011","journal-title":"Pacing Clin Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C14","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.hrthm.2009.07.009","article-title":"Upgrade and de novo cardiac resynchronization therapy: impact of paced or intrinsic QRS morphology on outcomes and survival","volume":"6","author":"Wokhlu","year":"2009","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170624061732_EUT049C15","volume-title":"Marriott's Practical Electrocardiograpy","author":"Wagner","year":"2008"},{"key":"key\n\t\t\t\t20170624061732_EUT049C16","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.amjcard.2010.11.010","article-title":"Defining left bundle branch block in the era of cardiac resynchronization therapy","volume":"107","author":"Strauss","year":"2011","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C17","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jelectrocard.2012.06.008","article-title":"Should electrocardiogram criteria for the diagnosis of left bundle-branch block be revised?","volume":"45","author":"Gettes","year":"2012","journal-title":"J Electrocardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C18","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.jacc.2005.04.069","article-title":"Left ventricular dyssynchrony predicts right ventricular remodeling after cardiac resynchronization therapy","volume":"46","author":"Bleeker","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S0894-7317(89)80014-8","article-title":"Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, subcommittee on quantitation of two-dimensional echocardiograms","volume":"2","author":"Schiller","year":"1989","journal-title":"J Am Soc Echocardiogr"},{"key":"key\n\t\t\t\t20170624061732_EUT049C20","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jacc.2004.09.058","article-title":"Ventricular asynchrony predicts a better outcome in patients with chronic heart failure receiving cardiac resynchronization therapy","volume":"45","author":"Pitzalis","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C21","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/j.jacc.2006.07.046","article-title":"Delayed enhancement magnetic resonance imaging predicts response to cardiac resynchronization therapy in patients with intraventricular dyssynchrony","volume":"48","author":"White","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C22","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.hrthm.2010.04.005","article-title":"Characterization of super-response to cardiac resynchronization therapy","volume":"7","author":"Rickard","year":"2010","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170624061732_EUT049C23","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.hrthm.2007.09.023","article-title":"Cardiac resynchronization therapy: \u2018nonresponders\u2019 and \u2018hyperresponders","volume":"5","author":"Castellant","year":"2008","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170624061732_EUT049C24","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/j.amjcard.2007.06.071","article-title":"Usefulness of QRS duration to predict response to cardiac resynchronization therapy in patients with end-stage heart failure","volume":"100","author":"Mollema","year":"2007","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C25","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1161\/01.CIR.0000118502.91105.F6","article-title":"Characterization of left ventricular activation in patients with heart failure and left bundle-branch block","volume":"109","author":"Auricchio","year":"2004","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170624061732_EUT049C26","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1161\/CIRCULATIONAHA.110.956011","article-title":"Bundle-branch block morphology and other predictors of outcome after cardiac resynchronization therapy in Medicare patients","volume":"122","author":"Bilchick","year":"2010","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170624061732_EUT049C27","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/j.1540-8167.2009.01714.x","article-title":"The surface electrocardiogram predicts risk of heart block during right heart catheterization in patients with preexisting left bundle branch block: implications for the definition of complete left bundle branch block","volume":"21","author":"Padanilam","year":"2010","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C28","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/europace\/eur381","article-title":"Greater response to cardiac resynchronization therapy in patients with true complete left bundle branch block: a PREDICT substudy","volume":"14","author":"Perrin","year":"2012","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170624061732_EUT049C29","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jelectrocard.2012.09.001","article-title":"Differentiation between left bundle branch block and left ventricular hypertrophy: Implications for cardiac resynchronization therapy","volume":"45","author":"Strauss","year":"2012","journal-title":"J Electrocardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C30","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/j.1540-8159.2012.03427.x","article-title":"Electrocardiographic criteria of true left bundle branch block: a simple sign to predict a better clinical and instrumental response to CRT","volume":"35","author":"Mascioli","year":"2012","journal-title":"Pacing Clin Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C31","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1093\/europace\/eup038","article-title":"Identification of \u2018super-responders\u2019 to cardiac resynchronization therapy: the importance of symptom duration and left ventricular geometry","volume":"11","author":"Antonio","year":"2009","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170624061732_EUT049C32","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1111\/j.1540-8167.2011.02018.x","article-title":"Predicting hyperresponse among pacemaker-dependent nonischemic cardiomyopathy patients upgraded to cardiac resynchronization","volume":"22","author":"Adelstein","year":"2011","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C33","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1016\/j.jacc.2012.01.065","article-title":"Predictors of super-response to cardiac resynchronization therapy and associated improvement in clinical outcome: the MADIT-CRT (multicenter automatic defibrillator implantation trial with cardiac resynchronization therapy) study","volume":"59","author":"Hsu","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C34","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1093\/eurheartj\/ehp368","article-title":"Characteristics of heart failure patients associated with good and poor response to cardiac resynchronization therapy: a PROSPECT (Predictors of Response to CRT) sub-analysis","volume":"30","author":"van Bommel","year":"2009","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20170624061732_EUT049C35","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/j.hrthm.2008.10.019","article-title":"Fragmented QRS: a predictor of mortality and sudden cardiac death","volume":"6","author":"Das","year":"2009","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170624061732_EUT049C36","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1161\/CIRCEP.107.763284","article-title":"Fragmented wide QRS on a 12-lead ECG: a sign of myocardial scar and poor prognosis","volume":"1","author":"Das","year":"2008","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C37","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/clc.22061","article-title":"Number of Leads With Fragmented QRS Predicts Response to Cardiac Resynchronization Therapy","volume":"36","author":"Celikyurt","year":"2013","journal-title":"Clin Cardiol"},{"key":"key\n\t\t\t\t20170624061732_EUT049C38","first-page":"1441","article-title":"Appendix 1: normal limits","volume-title":"Comprehensive Electrocardiology: Theory and Practice in Health and Disease","author":"Macfarlane","year":"1989"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/15\/10\/1499\/17858004\/eut049.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T23:27:08Z","timestamp":1715038028000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article-lookup\/doi\/10.1093\/europace\/eut049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,6]]},"references-count":38,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,3,6]]},"published-print":{"date-parts":[[2013,10]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/eut049","relation":{},"ISSN":["1532-2092","1099-5129"],"issn-type":[{"value":"1532-2092","type":"electronic"},{"value":"1099-5129","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3,6]]}}}