{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T21:01:52Z","timestamp":1788037312061,"version":"build-2784847793"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1093\/europace\/euw262","type":"journal-article","created":{"date-parts":[[2017,2,12]],"date-time":"2017-02-12T02:52:35Z","timestamp":1486867955000},"page":"378-384","source":"Crossref","is-referenced-by-count":72,"title":["Cryoballoon vs. radiofrequency ablation for paroxysmal atrial fibrillation: an updated meta-analysis of randomized and observational studies"],"prefix":"10.1093","volume":"19","author":[{"given":"Alessandra","family":"Buiatti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gesa","family":"von Olshausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Barthel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Luik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Kaess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Ludwig","family":"Laugwitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Hoppmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,10,4]]},"reference":[{"key":"key\n\t\t\t\t20170308000526_euw262C1","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S0140-6736(14)61774-8","article-title":"50 Year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study","volume":"386","year":"2015","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170308000526_euw262C2","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1161\/01.CIR.98.10.946","article-title":"Impact of atrial fibrillation on the risk of death: the Framingham Heart Study","volume":"98","year":"1998","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170308000526_euw262C3","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1093\/europace\/eus305","article-title":"2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation\u2014developed with the special contribution of the European Heart Rhythm Association","volume":"14","year":"2012","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C4","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1056\/NEJM199809033391003","article-title":"Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins","volume":"339","year":"1998","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170308000526_euw262C5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/jce.12267","article-title":"Cryoballoon versus RF ablation in paroxysmal atrial fibrillation: results from the German Ablation Registry","volume":"25","year":"2014","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","year":"2003","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20170308000526_euw262C7","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1161\/CIRCULATIONAHA.115.016871","article-title":"Cryoballoon versus open irrigated radiofrequency ablation in patients with paroxysmal atrial fibrillation: the prospective, randomized, controlled, noninferiority FreezeAF study","volume":"132","year":"2015","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170308000526_euw262C8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.hrthm.2013.10.014","article-title":"The COR trial: a randomized study with continuous rhythm monitoring to compare the efficacy of cryoenergy and radiofrequency for pulmonary vein isolation","volume":"11","year":"2014","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170308000526_euw262C9","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1056\/NEJMoa1602014","article-title":"Cryoballoon or radiofrequency ablation for paroxysmal atrial fibrillation","volume":"374","year":"2016","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170308000526_euw262C10","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/europace\/euv271","article-title":"First-line catheter ablation of paroxysmal atrial fibrillation: outcome of radiofrequency vs. cryoballoon pulmonary vein isolation","volume":"18","year":"2016","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C11","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/pace.12582","article-title":"Cryoballoon versus radiofrequency catheter ablation for paroxysmal atrial fibrillation","volume":"38","year":"2015","journal-title":"Pacing Clin Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C12","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1016\/j.hrthm.2010.08.028","article-title":"Cryoballoon versus radiofrequency catheter ablation of paroxysmal atrial fibrillation: biomarkers of myocardial injury, recurrence rates, and pulmonary vein reconnection patterns","volume":"7","year":"2010","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170308000526_euw262C13","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ijcard.2014.06.038","article-title":"Long-term comparison of cryoballoon and radiofrequency ablation of paroxysmal atrial fibrillation: a propensity score matched analysis","volume":"176","year":"2014","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C14","article-title":"Outcomes after cryoablation vs. radiofrequency in patients with paroxysmal atrial fibrillation: impact of pulmonary veins anatomy","year":"2016","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C15","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/europace\/euu215","article-title":"Contact-force guided radiofrequency vs. second-generation balloon cryotherapy for pulmonary vein isolation in patients with paroxysmal atrial fibrillation-a prospective evaluation","volume":"17","year":"2015","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C16","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1093\/europace\/eus027","article-title":"2012 HRS\/EHRA\/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design","volume":"14","year":"2012","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C17","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/j.jacc.2012.11.064","article-title":"Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial","volume":"61","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C18","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1016\/j.hrthm.2011.03.050","article-title":"Efficacy and safety of cryoballoon ablation for atrial fibrillation: a systematic review of published studies","volume":"8","year":"2011","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170308000526_euw262C19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/CIRCEP.113.000899","article-title":"Comparison of the first and second cryoballoon: high-volume single-center safety and efficacy analysis","volume":"7","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C20","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1111\/j.1540-8167.2009.01560.x","article-title":"Comparison of cryoballoon and radiofrequency ablation of pulmonary veins in 40 patients with paroxysmal atrial fibrillation: a case-control study","volume":"20","year":"2009","journal-title":"J Cardiovasc Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C21","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1136\/hrt.2009.192419","article-title":"Pulmonary venous isolation by antral ablation with a large cryoballoon for treatment of paroxysmal and persistent atrial fibrillation: medium-term outcomes and non-randomised comparison with pulmonary venous isolation by radiofrequency ablation","volume":"96","year":"2010","journal-title":"Heart"},{"key":"key\n\t\t\t\t20170308000526_euw262C22","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.hrthm.2011.09.017","article-title":"Cellular damage, platelet activation, and inflammatory response after pulmonary vein isolation: a randomized study comparing radiofrequency ablation with cryoablation","volume":"9","year":"2012","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170308000526_euw262C23","first-page":"486","article-title":"Atrial fibrillation ablation: a single center comparison between remote magnetic navigation, cryoballoon and conventional manual pulmonary vein isolation","volume":"10","year":"2010","journal-title":"Indian Pacing Electrophysiol J"},{"key":"key\n\t\t\t\t20170308000526_euw262C24","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1093\/europace\/eut104","article-title":"Ablation of atrial fibrillation with cryoballoon or duty-cycled radiofrequency pulmonary vein ablation catheter: a randomized controlled study comparing the clinical outcome and safety; the AF-COR study","volume":"15","year":"2013","journal-title":"Europace"},{"key":"key\n\t\t\t\t20170308000526_euw262C25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s10840-010-9518-0","article-title":"Pulmonary vein isolation with Mesh Ablator versus cryoballoon catheters: 6-month outcomes","volume":"29","year":"2010","journal-title":"J Interv Card Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C26","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.ijcard.2014.12.002","article-title":"The long-term efficacy of cryoballoon vs irrigated radiofrequency ablation for the treatment of atrial fibrillation: a meta-analysis","volume":"181","year":"2015","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C27","doi-asserted-by":"crossref","first-page":"e90323","DOI":"10.1371\/journal.pone.0090323","article-title":"Is cryoballoon ablation preferable to radiofrequency ablation for treatment of atrial fibrillation by pulmonary vein isolation? A meta-analysis","volume":"9","year":"2014","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170308000526_euw262C28","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.hrthm.2015.12.007","article-title":"German ablation registry: Cryoballoon vs radiofrequency ablation in paroxysmal atrial fibrillation-One-year outcome data","volume":"13","year":"2016","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20170308000526_euw262C29","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10840-015-0075-4","article-title":"Safety and efficacy of second-generation versus first-generation cryoballoons for treatment of atrial fibrillation: a meta-analysis of current evidence","volume":"45","year":"2016","journal-title":"J Interv Card Electrophysiol"},{"key":"key\n\t\t\t\t20170308000526_euw262C30","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/europace\/euu048","article-title":"Second-generation cryoballoon ablation for paroxysmal atrial fibrillation: a step forward?","volume":"16","year":"2014","journal-title":"Europace"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/19\/3\/378\/10872099\/euw262.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T14:37:08Z","timestamp":1503585428000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/2952422\/Cryoballoon"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,4]]},"references-count":30,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,10,4]]},"published-print":{"date-parts":[[2017,3]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euw262","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,4]]}}}