{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:32:20Z","timestamp":1788827540793,"version":"build-2803163510"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T00:00:00Z","timestamp":1554940800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010479","name":"Cook Medical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Spectranetics"},{"DOI":"10.13039\/100015345","name":"Zoll","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100015345","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>A sub-analysis of the ESC-EHRA European Lead Extraction ConTRolled (ELECTRa) Registry to evaluate the clinical impact of antithrombotic (AT) on transvenous lead extraction (TLE) safety and efficacy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>ELECTRa outcomes were compared between patients without AT therapy (No AT Group) and with different pre-operative AT regimens, including antiplatelets (AP), anticoagulants (AC), or both (AP + AC). Out of 3510 pts, 2398 (68%) were under AT pre-operatively. AT patients were older with more comorbidities (P\u2009&lt;\u20090.0001). AT subgroups, defined as AP, AC, or AP\u2009+\u2009AC, were 1096 (31.2%), 985 (28%), and 317 (9%), respectively. Regarding AP patients, 1413 (40%) were under AP, 1292 (91%) with a single AP, interrupted in 26% about 3.8\u2009\u00b1\u20093.7\u2009days before TLE. In total, 1302 (37%) patients were under AC, 881 vitamin K antagonist (68%), 221 (17%) direct oral anticoagulants, 155 (12%) low weight molecular heparin, and 45 (3.5%) unfractionated heparin. AC was \u2018interrupted without bridging\u2019 in 696 (54%) and \u2018interrupted with bridging\u2019 in 504 (39%) about 3.3\u2009\u00b1\u20092.3\u2009days before TLE, and \u2018continued\u2019 in 87 (7%). TLE success rate was high in all subgroups. Only overall in-hospital death (1.4%), but not the procedure-related one, was higher in the AT subgroups (P\u2009=\u20090.0500). Age &gt;65\u2009years and New York Heart Association Class III\/IV, but not AT regimens, were independent predictors of death for any cause. Haematomas were more frequent in AT subgroups, especially in AC \u2018continued\u2019 (P\u2009=\u20090.025), whereas pulmonary embolism in the No-AT (P\u2009&lt;\u20090.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>AT minimization is safe in patients undergoing TLE. AT does not seem to predict death but identifies a subset of fragile patients with a worse in-hospital TLE outcome.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euz062","type":"journal-article","created":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T04:25:39Z","timestamp":1552364739000},"page":"1096-1105","source":"Crossref","is-referenced-by-count":12,"title":["Clinical impact of antithrombotic therapy in transvenous lead extraction complications: a sub-analysis from the ESC-EORP EHRA ELECTRa (European Lead Extraction ConTRolled) Registry"],"prefix":"10.1093","volume":"21","author":[{"given":"Andrea","family":"Di Cori","sequence":"first","affiliation":[{"name":"Second Division of Cardiology, Department of Cardiac-Thoracic & Vascular, Azienda Ospedaliera Pisana, Via Paradisa 2, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Auricchio","sequence":"additional","affiliation":[{"name":"Fondazione Cardiocentro Ticino, Via Tesserete 48, Lugano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Regoli","sequence":"additional","affiliation":[{"name":"Fondazione Cardiocentro Ticino, Via Tesserete 48, Lugano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Blomstr\u00f6m-Lundqvist","sequence":"additional","affiliation":[{"name":"Department of Medical Science and Cardiology, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Butter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Brandenburg in Bernau\/Berlin & Brandenburg Medical School, Ladeburger Stra\u00dfe 17, Bernau, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Dagres","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Deharo","sequence":"additional","affiliation":[{"name":"CHU La Timone, Cardiologie, Service du prof Deharo, 264 Rue Saint Pierre, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo P","family":"Maggioni","sequence":"additional","affiliation":[{"name":"EURObservational Research Programme (EORP), European Society of Cardiology, 2035 routes des Colles, Sophia Antipolis, France"},{"name":"ANMCO Research Center, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Kutarski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical University of Lublin, Jaczerskiego Street Nr 8, Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Kennergren","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Sahlgrenska\/SU, Goteborg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Laroche","sequence":"additional","affiliation":[{"name":"EURObservational Research Programme (EORP), European Society of Cardiology, 2035 routes des Colles, Sophia Antipolis, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"St Thomas Hospital, Westminster Bridge Road, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio Vincenzo","family":"Dovellini","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Cardiothoracic and Vascular, Careggi University Hospital, Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Giorgio","family":"Golzio","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, A.O.U. 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