{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:35:31Z","timestamp":1769124931390,"version":"3.49.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T00:00:00Z","timestamp":1568246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims\u2003<\/jats:title>\n                  <jats:p>To determine the clinical utility of a combined single-session cardiovascular magnetic resonance (CMR) imaging protocol integrating adenosine stress perfusion and three-dimensional pulmonary vein angiography for stratification of atrial fibrillation (AF) patients referred for pulmonary vein isolation (PVI) and complaining about chest pain syndromes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results\u2003<\/jats:title>\n                  <jats:p>The preprocedural CMR examination (adenosine stress perfusion, late gadolinium enhancement, and three-dimensional pulmonary vein angiography) was performed in 357 consecutive AF patients with chest pain syndromes referred for PVI. Stress perfusion results were used for stratification: ischaemia positive patients underwent invasive coronary angiography, ischaemia negative patients underwent PVI, and follow-up\/outcome data were collected (combined primary endpoint of cardiac death\/non-fatal myocardial infarction). The integrated CMR protocol had a high success rate (356\/357, 99.7%), a short total examination duration (&lt;30\u2009min in all patients), and delivered high-quality three-dimensional pulmonary vein angiography in all patients undergoing PVI (324\/324, 100%). Variants of pulmonary vein anatomy were identified in 33% of all patients (117\/357). Stress positivity (28\/356, 8%) had a high positive predictive value for identification of obstructive coronary artery disease (86%), while stress negativity carried a low short-term event rate following PVI (cumulative 1-year event-free survival rate, 99.6%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion\u2003<\/jats:title>\n                  <jats:p>Combined single-session CMR as a routine diagnostic workup for AF patients with chest pain syndromes prior to PVI proved to represent a time-efficient and effective stratification tool.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euz248","type":"journal-article","created":{"date-parts":[[2019,8,15]],"date-time":"2019-08-15T15:11:49Z","timestamp":1565881909000},"page":"1809-1816","source":"Crossref","is-referenced-by-count":8,"title":["Combined single-session cardiovascular magnetic resonance: stress perfusion and three-dimensional pulmonary vein angiography for stratification of atrial fibrillation patients with chest pain syndromes prior to catheter ablation"],"prefix":"10.1093","volume":"21","author":[{"given":"Sabrina","family":"Oebel","sequence":"first","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Paetsch","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Stegmann","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Kircher","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Sommer","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Arya","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Lindemann","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Bollmann","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7610-1156","authenticated-orcid":false,"given":"Gerhard","family":"Hindricks","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cosima","family":"Jahnke","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Heart Center Leipzig, University of Leipzig, Struempellstr. 39, 04289 Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,9,12]]},"reference":[{"key":"2019120303504656000_euz248-B1","doi-asserted-by":"crossref","first-page":"e24964.","DOI":"10.1371\/journal.pone.0024964","article-title":"Incidence and severity of coronary artery disease in patients with atrial fibrillation undergoing first-time coronary angiography","volume":"6","author":"Kralev","year":"2011","journal-title":"PLoS One"},{"key":"2019120303504656000_euz248-B2","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jacc.2010.05.067","article-title":"Dynamic 3-dimensional stress cardiac magnetic resonance perfusion imaging: detection of coronary artery disease and volumetry of myocardial hypoenhancement before and after coronary stenting","volume":"57","author":"Manka","year":"2011","journal-title":"J Am Coll 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Imaging"},{"key":"2019120303504656000_euz248-B16","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.advms.2017.06.005","article-title":"Patients with atrial fibrillation and coronary artery disease\u2014double trouble","volume":"63","author":"Michniewicz","year":"2018","journal-title":"Adv Med Sci"}],"container-title":["EP 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