{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:02:30Z","timestamp":1790298150058,"version":"4.1.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2019,11,14]],"date-time":"2019-11-14T00:00:00Z","timestamp":1573689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Our study assesses the value of electrograms (EGMs) characteristics to identify a ventricular tachycardia (VT) isthmus entrance in patients with post-infarct VT. Post-infarct VTs are mostly due to a re-entrant circuit. A pacemapping (PM) approach is able to localize the VT isthmus during sinus rhythm. Limited data are available about the role of local EGMs in defining VT isthmus location.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Twenty consecutive patients (70% male) referred for post-infarct VT catheter ablation were included in the present study. The VT isthmus was defined according to the PM method. At each recording site, 10 characteristics of the local EGM were assessed to predict the location of the VT isthmus entrance. In total, 924 EGMs were acquired, of which 127 were located in the VT isthmus entrance. Logistic regression analysis showed that bipolar voltage, number of EGM positive peaks, and sQRS interval were independently associated with VT isthmus entrance location. The ROC curve best fitted the model at the cut-off 0.1641 (sensitivity 72%, specificity 75.2%, positive predictive value 31.3%, negative predictive value 94.4%, area under the curve 0.78, P\u2009&lt;\u20090.001). Based upon these results, we developed an algorithm implemented in an automatic calculator to determine the likelihood that an EGM is located at a VT isthmus entrance.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our study suggests that three EGM characteristics: bipolar voltage, number of positive peaks, and sQRS interval can successfully identify a VT isthmus entrance in post-infarct patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euz315","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T19:13:02Z","timestamp":1571944382000},"source":"Crossref","is-referenced-by-count":3,"title":["An efficient algorithm based on electrograms characteristics to identify ventricular tachycardia isthmus entrance in post-infarct patients"],"prefix":"10.1093","author":[{"given":"Alberto","family":"Battaglia","sequence":"first","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, Nancy F-54500, France"},{"name":"CIC-IT, Universit\u00e9 de Lorraine, INSERM, CHRU Nancy, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freddy","family":"Odille","sequence":"additional","affiliation":[{"name":"CIC-IT, Universit\u00e9 de Lorraine, INSERM, CHRU Nancy, Nancy F-54500, France"},{"name":"IADI, Universit\u00e9 de Lorraine, INSERM, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Magnin-Poull","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Sellal","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, Nancy F-54500, France"},{"name":"IADI, Universit\u00e9 de Lorraine, INSERM, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Hoyland","sequence":"additional","affiliation":[{"name":"CIC-IT, Universit\u00e9 de Lorraine, INSERM, CHRU Nancy, Nancy F-54500, France"},{"name":"IADI, Universit\u00e9 de Lorraine, INSERM, Nancy F-54500, France"},{"name":"Biosense Webster France, Johnson & Johnson, Issy les Moulineaux F-92787, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren","family":"Hooks","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Wellington Hospital, Wellington, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Voilliot","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, Nancy F-54500, France"},{"name":"CIC-IT, Universit\u00e9 de Lorraine, INSERM, CHRU Nancy, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Felblinger","sequence":"additional","affiliation":[{"name":"CIC-IT, Universit\u00e9 de Lorraine, INSERM, CHRU Nancy, Nancy F-54500, France"},{"name":"IADI, Universit\u00e9 de Lorraine, INSERM, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"de Chillou","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, CHRU de Nancy, Nancy F-54500, France"},{"name":"IADI, Universit\u00e9 de Lorraine, INSERM, Nancy F-54500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,11,14]]},"reference":[{"key":"2019111409585514700_euz315-B1","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1161\/01.CIR.66.4.847","article-title":"Intra-operative electrophysiologic mapping of the ventricle during sinus rhythm in patients with a previous myocardial infarction: 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