{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:16:11Z","timestamp":1790280971244,"version":"4.1.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T00:00:00Z","timestamp":1581120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"government of Rhineland-Palatinate"},{"DOI":"10.13039\/501100004346","name":"Stiftung Rheinland-Pfalz f\u00fcr Innovation","doi-asserted-by":"publisher","award":["AZ 961-386261\/733"],"award-info":[{"award-number":["AZ 961-386261\/733"]}],"id":[{"id":"10.13039\/501100004346","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wissen schafft Zukunft"},{"name":"Center for Translational Vascular Biology"},{"DOI":"10.13039\/501100004033","name":"Johannes Gutenberg-University of Mainz","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004033","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100024099","name":"PHILIPS Medical Systems","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100024099","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research","doi-asserted-by":"publisher","award":["BMBF 01E01503"],"award-info":[{"award-number":["BMBF 01E01503"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cross-sectional studies have shown that noise annoyance is strongly associated with mental distress, however, its long-term effects on mental health is unknown. We therefore investigated whether noise annoyance predicts depression, anxiety and sleep disturbance in a large, representative sample 5 years later.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We investigated longitudinal data of N = 11\u00a0905 participants of the Gutenberg Health Study, a population-based, prospective, single-centre cohort study in mid-Germany (age at baseline 35\u201374 years). Noise annoyance was assessed at baseline and 5-year follow-up (sources: road traffic, aircraft, railways, industrial, neighbourhood indoor and outdoor noise; and day vs. nighttime). Depression, anxiety and sleep disturbance were assessed using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-2. Participants suffering from depression, anxiety or sleep disturbance at baseline were excluded from the respective multivariate analyses of new onset at follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>General noise annoyance remained stable. Daytime noise annoyance predicted new onset of depressive, anxiety symptoms (also nighttime annoyance) and sleep disturbance (beyond respective baseline scores). Additional predictors were female sex, lower age and low socioeconomic status (SES). Regarding specific sources, daytime baseline aircraft annoyance predicted depression and anxiety. Sleep disturbance was most consistently predicted by neighbourhood annoyance (baseline and follow-up) and follow-up annoyance by aircraft (night) and road traffic (day and night).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We identified current and past noise annoyances as risk factors for mental distress and sleep disturbance. Furthermore, women, younger adults and those with lower SES are particularly susceptible to noise annoyance. Our results indicate the need to provide regulatory measures in affected areas to prevent mental health problems.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurpub\/ckaa015","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T15:09:09Z","timestamp":1579619349000},"page":"516-521","source":"Crossref","is-referenced-by-count":108,"title":["Noise annoyance predicts symptoms of depression, anxiety and sleep disturbance 5 years later. Findings from the Gutenberg Health Study"],"prefix":"10.1093","volume":"30","author":[{"given":"Manfred E","family":"Beutel","sequence":"first","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Br\u00e4hler","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4952-9717","authenticated-orcid":false,"given":"Mareike","family":"Ernst","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Klein","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Reiner","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Wiltink","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Michal","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]},{"name":"DZHK (German Center for Cardiovascular Research) , partner site Rhine-Main, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp S","family":"Wild","sequence":"additional","affiliation":[{"name":"DZHK (German Center for Cardiovascular Research) , partner site Rhine-Main, Mainz,","place":["Germany"]},{"name":"Preventive Cardiology and Preventive Medicine , Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]},{"name":"Center for Thrombosis and Hemostasis , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schulz","sequence":"additional","affiliation":[{"name":"Preventive Cardiology and Preventive Medicine , Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"M\u00fcnzel","sequence":"additional","affiliation":[{"name":"DZHK (German Center for Cardiovascular Research) , partner site Rhine-Main, Mainz,","place":["Germany"]},{"name":"Center for Cardiology - Cardiology I , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Hahad","sequence":"additional","affiliation":[{"name":"Center for Cardiology - Cardiology I , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochem","family":"K\u00f6nig","sequence":"additional","affiliation":[{"name":"Institute for Medical Biostatistics , Epidemiology and Informatics, University Medical Center Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl J","family":"Lackner","sequence":"additional","affiliation":[{"name":"Institute of Clinical Chemistry and Laboratory Medicine , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Pfeiffer","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana N","family":"Tibubos","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy , University Medical Center of the Johannes Gutenberg-University Mainz, Mainz,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,8]]},"reference":[{"key":"2025092906070330600_ckaa015-B1","first-page":"41","article-title":"Aviation noise impacts: state of the science","volume":"19","author":"Basner","year":"2017","journal-title":"Noise Health"},{"key":"2025092906070330600_ckaa015-B2","year":"2018"},{"key":"2025092906070330600_ckaa015-B3","doi-asserted-by":"crossref","first-page":"e0155357","DOI":"10.1371\/journal.pone.0155357","article-title":"Noise annoyance is associated with depression and anxiety in the general population\u2014the contribution of aircraft noise","volume":"11","author":"Beutel","year":"2016","journal-title":"PLoS One"},{"key":"2025092906070330600_ckaa015-B4","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.3390\/ijerph14121539","article-title":"WHO Environmental Noise Guidelines for the European Region: a systematic review on environmental noise and annoyance","volume":"14","author":"Guski","year":"2017","journal-title":"Int J Environ Res Public Health"},{"key":"2025092906070330600_ckaa015-B5","doi-asserted-by":"crossref","first-page":"954","DOI":"10.3390\/ijerph13100954","article-title":"Environmental Noise Annoyance and Mental Health in Adults: findings from the Cross-Sectional German Health Update (GEDA) Study 2012","volume":"13","author":"Hammersen","year":"2016","journal-title":"Int J Environ Res Public Health"},{"key":"2025092906070330600_ckaa015-B6","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.envint.2016.03.011","article-title":"Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity","volume":"91","author":"Foraster","year":"2016","journal-title":"Environ Int"},{"key":"2025092906070330600_ckaa015-B7","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1136\/oem.2010.058586","article-title":"Medication use in relation to noise from aircraft and road traffic in six European countries: results of the HYENA study","volume":"68","author":"Floud","year":"2011","journal-title":"Occup Environ Med"},{"key":"2025092906070330600_ckaa015-B8","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1017\/S003329170005337X","article-title":"Aircraft noise and mental health: II. 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