{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:51:31Z","timestamp":1768557091985,"version":"3.49.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Competitive State Research Financing of the Expert Responsibility area of Tampere University Hospital"},{"DOI":"10.13039\/501100003128","name":"Finnish work environment fund","doi-asserted-by":"publisher","award":["190306"],"award-info":[{"award-number":["190306"]}],"id":[{"id":"10.13039\/501100003128","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>This study aimed to identify trajectories of low back pain (LBP) over a 16-year follow-up from midlife to retirement and investigate their association with mobility limitations and disability in activities of daily living (ADL-disability) in later life.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The study population consisted of 6257 baseline (1981) respondents aged 44\u201358\u2009years from Finnish Longitudinal study on Aging Municipal Employees. Repeated measurements of LBP were collected in 1985, 1992 and 1997. We studied persons who had data on LBP at baseline and in at least one of the follow-ups and had information on mobility limitations (n\u2009=\u20092305) and ADL-disability (n\u2009=\u20092359) at a 28-year follow-up in 2009. Latent class growth analysis was used to identify LBP trajectories. Odds ratios (ORs) with 95% confidence intervals (CIs) for the associations of LBP trajectory and later life mobility limitations and ADL-disability were estimated and adjusted for confounders.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Three LBP trajectories with parallel shapes were identified: high-decreasing (19%), intermediate-stable (60%) and low (21%). After adjustment for confounders, high-decreasing trajectory had 3.2 times the odds (95% CI 2.1\u20134.9) of mobility limitations and 2.9 times the odds (95% CI 2.0\u20134.2) of ADL-disability as compared to low trajectory. The respective ORs for intermediate-stable trajectory were 1.6 (95% CI 1.2\u20132.1) and 1.7 (95% CI 1.3\u20132.3).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Among majority of respondents, LBP remained stable over the follow-up. The respondents belonging to intermediate-stable and high-decreasing trajectories of LBP had higher odds of mobility limitations and ADL-disability at old age. This highlights that LBP during midlife to retirement has far-reached consequences on functional ability at old age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurpub\/ckab191","type":"journal-article","created":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T19:20:04Z","timestamp":1635276004000},"page":"497-503","source":"Crossref","is-referenced-by-count":9,"title":["Trajectories of low back pain from midlife to retirement and functional ability at old age"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4610-1184","authenticated-orcid":false,"given":"Saila M","family":"Kyr\u00f6nlahti","sequence":"first","affiliation":[{"name":"Unit of Health Sciences, Faculty of Social Sciences, Tampere University , Tampere, Finland"},{"name":"Gerontology Research Center, Tampere University , Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clas-H\u00e5kan","family":"Nyg\u00e5rd","sequence":"additional","affiliation":[{"name":"Unit of Health Sciences, Faculty of Social Sciences, Tampere University , Tampere, Finland"},{"name":"Gerontology Research Center, Tampere University , Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"K. C","sequence":"additional","affiliation":[{"name":"Unit of Health Sciences, Faculty of Social Sciences, Tampere University , Tampere, Finland"},{"name":"Gerontology Research Center, Tampere University , Tampere, Finland"},{"name":"Department of Public Health, University of Turku and Turku University Hospital , Turku, Finland"},{"name":"Department of Psychology, Stress Research Institute , Stockholm University, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subas","family":"Neupane","sequence":"additional","affiliation":[{"name":"Unit of Health Sciences, Faculty of Social Sciences, Tampere University , Tampere, Finland"},{"name":"Gerontology Research Center, Tampere University , Tampere, Finland"},{"name":"Tampere University Hospital , Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"2022060114434853600_ckab191-B1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/annrheumdis-2013-204428","article-title":"The global burden of low back pain: estimates from the global burden of disease 2010 study","volume":"73","author":"Hoy","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"2022060114434853600_ckab191-B2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.berh.2010.10.002","article-title":"The epidemiology of low back pain","volume":"24","author":"Hoy","year":"2010","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"2022060114434853600_ckab191-B3","first-page":"297","article-title":"Work ability and low back pain among workers from a public health institution","volume":"30","author":"Monteiro","year":"2009","journal-title":"Rev Gaucha Enferm"},{"key":"2022060114434853600_ckab191-B4","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/occmed\/kqu190","article-title":"Combined effect of back pain and stress on work ability","volume":"65","author":"Oberlinner","year":"2015","journal-title":"Occup Med (Lond)"},{"key":"2022060114434853600_ckab191-B5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jad.2014.04.036","article-title":"Common mental and musculoskeletal disorders as predictors of disability retirement among Finns","volume":"165","author":"Kaila-Kangas","year":"2014","journal-title":"J Affect Disord"},{"key":"2022060114434853600_ckab191-B6","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.berh.2015.08.002","article-title":"Economic impact of musculoskeletal disorders (MSDs) on work in Europe","volume":"29","author":"Bevan","year":"2015","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"2022060114434853600_ckab191-B7","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990\u20132015: a systematic analysis for the global burden of disease study 2015","volume":"388","author":"Vos","year":"2016","journal-title":"Lancet"},{"key":"2022060114434853600_ckab191-B8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/s12891-016-1071-2","article-title":"What have we learned from ten years of trajectory research in low back pain?","volume":"17","author":"Kongsted","year":"2016","journal-title":"BMC Musculoskelet Disord"},{"key":"2022060114434853600_ckab191-B9","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1471-2474-11-23","article-title":"Extending conceptual frameworks: life course epidemiology for the study of back pain","volume":"11","author":"Dunn","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"key":"2022060114434853600_ckab191-B10","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1016\/S0140-6736(18)30480-X","article-title":"What low back pain is and why we need to pay attention","volume":"391","author":"Hartvigsen","year":"2018","journal-title":"Lancet"},{"key":"2022060114434853600_ckab191-B11","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1093\/aje\/kwj100","article-title":"Characterizing the course of low back pain: a latent class analysis","volume":"163","author":"Dunn","year":"2006","journal-title":"Am J Epidemiol"},{"key":"2022060114434853600_ckab191-B12","doi-asserted-by":"crossref","first-page":"e003838","DOI":"10.1136\/bmjopen-2013-003838","article-title":"Long-term trajectories of back pain: cohort study with 7-year follow-up. 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