{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:21:18Z","timestamp":1791555678274,"version":"4.3.4"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Bartonella is a vector-borne zoonotic pathogen, which could also be transmitted directly and cause a variety of clinical illnesses. This study aimed to investigate the prevalence of Bartonella in countries in the WHO Eastern Mediterranean Region (WHO-EMR) region. We searched using the keywords Bartonella and the name of each country in the WHO-EMR in databases such as PubMed, ISI (Web of Science), Scopus, and Google Scholar, with a publication date range of 1990\u20132022 and limited to English articles. We evaluated the quality of the studies using the STROBE 6-item checklist and used the random effects model to integrate the findings of the included studies. A total of 45 papers out of 240 were included in the analysis. The results showed the prevalence of Bartonella infection among endocarditis patients was 3.8% (95% CI: 0.2\u20137.4) and the seroprevalence of Bartonella among other people was 27.5% (95% CI: 13.5\u201341.5). The overall prevalence of Bartonella spp. among animals, as determined by molecular, serological, and culture methods, was 11.9% (95% CI: 5.7\u201318.2), 38.9% (95% CI: 27.5\u201350.2), and 1.7% (95% CI: 0.5\u20132.9), respectively. Furthermore, the prevalence of Bartonella spp. in ectoparasites was 3.9% (95% CI: 3.5\u20135.2), with fleas (6.2%) showing a higher prevalence compared to lice (4.9%) and ticks (1.0%). The detection of Bartonella in all animal and ectoparasites species and human populations in the WHO-EMR with prevalence ranging from 0.3% to 23% is concerning, emphasizes the importance of conducting more comprehensive studies to gain a deeper understanding of the spread of Bartonella in these areas.<\/jats:p>","DOI":"10.1093\/eurpub\/ckae123","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T09:01:28Z","timestamp":1736758888000},"page":"i48-i54","source":"Crossref","is-referenced-by-count":6,"title":["Bartonellosis in World Health Organization Eastern Mediterranean Region, a systematic review and meta-analysis"],"prefix":"10.1093","volume":"35","author":[{"given":"Zahra","family":"Tahmasebi Ashtiani","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Tehran,","place":["Iran"]},{"name":"National Reference Laboratory of Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Hamadan,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahimeh","family":"Bagheri Amiri","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Tehran,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mozhgan","family":"Ahmadinezhad","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Tehran,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehsan","family":"Mostafavi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Tehran,","place":["Iran"]},{"name":"National Reference Laboratory of Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Hamadan,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saber","family":"Esmaeili","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , Tehran,","place":["Iran"]},{"name":"National Reference Laboratory of Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran , 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