{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:23:08Z","timestamp":1792034588626,"version":"4.4.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004954","name":"Augustinus Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004954","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004915","name":"Danish Kidney Association","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004915","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004824","name":"Danish Society of Nephrology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020219","name":"Helen and Ejnar Bj\u00f8rnow Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chronic kidney disease (CKD) affects 10\u201315% globally and is a marked independent risk factor for cardiovascular disease. Prevalence estimations are essential for public health planning and implementation of CKD treatment strategies. This study aimed to estimate the prevalence and stages of CKD in the population-based Lolland-Falster Health Study, set in a rural provincial area with the lowest socioeconomic status in Denmark. Additionally, the study characterized participants with CKD, evaluated the overall disease recognition, including the awareness of CKD and compared it with other common conditions. Cross-sectional data were obtained from clinical examinations, biochemical analyses, and questionnaires. CKD was defined as albuminuria (urine albumin\u2013creatinine ratio \u226530\u2009mg\/g), estimated glomerular filtration rate (eGFR) &amp;lt;60\u2009ml\/min\/1.73 m\u00b2, or by a diagnosis in the National Patient Register. Patient awareness was assessed by self-reported CKD, and overall disease recognition by either a registered hospital diagnosis or self-reported CKD. Among 16 097 adults (median age 58.6\u2009years), CKD prevalence was 18.0% (n\u2009=\u20092903), with 70.1% identified by albuminuria, 28.4% by reduced eGFR, and 1.5% by a registered diagnosis alone. Of those with CKD, 98.8% had stages 1\u20133 (eGFR \u226530\u2009ml\/min\/1.73 m\u00b2), and 1.2% had stages 4\u20135 (eGFR &amp;lt;30\u2009ml\/min\/1.73 m\u00b2). Female sex, comorbidities, smoking, and low socioeconomic parameters were independently associated with CKD. Patient awareness of CKD was 4.4%, compared to &amp;gt;50% for hypertension and &amp;gt;80% for diabetes, and the overall CKD recognition (self-reported or registered diagnosis) was 7.1%. Thus, in this population-based study, CKD was highly prevalent but poorly recognized, indicating great potential for preventing CKD progression and related complications.<\/jats:p>","DOI":"10.1093\/eurpub\/ckae208","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T12:32:08Z","timestamp":1733488328000},"page":"449-455","source":"Crossref","is-referenced-by-count":7,"title":["High prevalence of unrecognized chronic kidney disease in the Lolland-Falster Health Study: a population-based study in a rural provincial area of Denmark"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1398-3815","authenticated-orcid":false,"given":"Ebba","family":"Mannheimer","sequence":"first","affiliation":[{"name":"Department of Nephrology and Endocrinology, Rigshospitalet , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Buus J\u00f8rgensen","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Endocrinology, Rigshospitalet , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"Hommel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Holb\u00e6k Hospital , Holb\u00e6k,","place":["Denmark"]},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7523-6569","authenticated-orcid":false,"given":"Anne-Lise","family":"Kamper","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Endocrinology, Rigshospitalet , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0934-9850","authenticated-orcid":false,"given":"Randi","family":"Jepsen","sequence":"additional","affiliation":[{"name":"Lolland-Falster Health Study, Centre for Health Research, Zealand University Hospital , Nyk\u00f8bing F,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knud","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Lolland-Falster Health Study, Zealand University Hospital , Nyk\u00f8bing F,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8375-5211","authenticated-orcid":false,"given":"Lau Caspar","family":"Thygesen","sequence":"additional","affiliation":[{"name":"National Institute of Public Health, University of Southern Denmark , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Feldt-Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Endocrinology, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0123-4007","authenticated-orcid":false,"given":"Mads","family":"Hornum","sequence":"additional","affiliation":[{"name":"Department of Nephrology and Endocrinology, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"key":"2025062422124504200_ckae208-B1","first-page":"100438","article-title":"Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2\u00b74 million patients from 11 countries: the CaReMe CKD study","volume":"20","author":"Sundstr\u00f6m","year":"2022","journal-title":"Lancet"},{"key":"2025062422124504200_ckae208-B2","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1016\/S0140-6736(24)00367-2","article-title":"Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 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cardiovascular risk: epidemiology, mechanisms, and prevention","volume":"382","author":"Gansevoort","year":"2013","journal-title":"Lancet"},{"key":"2025062422124504200_ckae208-B6","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1093\/ndt\/gfw354","article-title":"Prevalence and recognition of chronic kidney disease in Stockholm healthcare","volume":"31","author":"Gasparini","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"2025062422124504200_ckae208-B7","doi-asserted-by":"crossref","first-page":"E067386","DOI":"10.1136\/bmjopen-2022-067386","article-title":"Prevalence of undiagnosed stage 3 chronic kidney disease in France, Germany, Italy, Japan and the USA: results from the multinational observational REVEAL-CKD study","volume":"13","author":"Tangri","year":"2023","journal-title":"BMJ Open"},{"key":"2025062422124504200_ckae208-B8","doi-asserted-by":"crossref","first-page":"E2326230","DOI":"10.1001\/jamanetworkopen.2023.26230","article-title":"Estimated 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