{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:51:23Z","timestamp":1791978683471,"version":"4.4.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"PROPHET"},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["101057721"],"award-info":[{"award-number":["101057721"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>There is currently no widely accepted framework to guide decision-making for preventive approaches using genetic and genomic technologies. In the context of the PROPHET project, we developed a multidimensional framework integrating Health Technology Assessment and Health Impact Assessment, complemented by a monitoring phase to assess the impact of policies implementing personalized prevention interventions. This integrated approach links technical, clinical, and societal dimensions, supporting prevention strategies that are effective, equitable and sustainable. The PROPHET framework supports policy makers in the equitable and efficient implementation of personalized prevention policies at scale.<\/jats:p>","DOI":"10.1093\/eurpub\/ckag180","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:43:32Z","timestamp":1790077412000},"source":"Crossref","is-referenced-by-count":0,"title":["Shaping public health policy in personalized prevention: the multidimensional PROPHET framework"],"prefix":"10.1093","volume":"36","author":[{"given":"Astrid Moura","family":"Vicente","sequence":"first","affiliation":[{"name":"Departament of Health Promotion and Non-communicable Disease Prevention, Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge , Lisbon,","place":["Portugal"]},{"name":"Lisbon, Portugal BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7227-2281","authenticated-orcid":false,"given":"Angelica","family":"Valz Gris","sequence":"additional","affiliation":[{"name":"Section of Hygiene, University Department of Life Sciences and Public Health, Universit\u00e0 Cattolica del Sacro Cuore , Rome,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3262-7066","authenticated-orcid":false,"given":"Cristina","family":"Costa","sequence":"additional","affiliation":[{"name":"Departament of Health Promotion and Non-communicable Disease Prevention, Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge , Lisbon,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Luis","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Departament of Health Promotion and Non-communicable Disease Prevention, Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge , Lisbon,","place":["Portugal"]},{"name":"Lisbon, Portugal BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Costa","sequence":"additional","affiliation":[{"name":"Departament of Health Promotion and Non-communicable Disease Prevention, Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge , Lisbon,","place":["Portugal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1tima","family":"Lopes","sequence":"additional","affiliation":[{"name":"Departament of Health Promotion and Non-communicable Disease Prevention, Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge , Lisbon,","place":["Portugal"]},{"name":"Lisbon, Portugal BioISI-Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pragathy","family":"Kannan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinical and Molecular Metabolism Research Program (CAMM), University of Helsinki , Helsinki,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4842-1667","authenticated-orcid":false,"given":"Markus","family":"Perola","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Clinical and Molecular Metabolism Research Program (CAMM), University of Helsinki , Helsinki,","place":["Finland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Pastorino","sequence":"additional","affiliation":[{"name":"Section of Hygiene, University Department of Life Sciences and Public Health, Universit\u00e0 Cattolica del Sacro Cuore , Rome,","place":["Italy"]},{"name":"Department of Woman and Child Health, Fondazione Policlinico Universitario A. 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