{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T08:28:29Z","timestamp":1793608109821,"version":"4.5.0"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"NSERC","doi-asserted-by":"publisher","award":["RPGIN-2018-06462"],"award-info":[{"award-number":["RPGIN-2018-06462"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Intralocus sexual conflict (IaSC) arises when selection favors different trait values in sexes sharing a genetic architecture. Sex-limited selection should allow one sex to adapt without constraint from selection on the other, with intersexual genetic correlations predicted to reduce opposite-sex fitness. In a recent study, male-limited (ML) selection produced the predicted decline in female fitness, but male fitness improvement depended on genetic background, suggesting unintended sources of adaptation. Here, we dissect these responses using a fully factorial assay spanning control- and selection-like conditions, while accounting for the unusual genetic features of the clone-generator (CG) breeding system and specialized CG females used to enforce ML inheritance. We establish substantial but context-dependent improvements in male fitness. Despite this context dependence, we show that phenotypic responses were remarkably consistent: selected males showed enhanced precopulatory traits, including higher mating success and shorter mating latency, while postcopulatory traits, including sperm offense and mate-induced fecundity, remained unchanged. Intriguingly, evolved males also caused substantially less harm to CG females. Together, these findings provide clearer evidence for IaSC, expressed as male-benefit\/female-detriment adaptations, while demonstrating that their magnitude and expression were also shaped by the\u00a0genetic manipulations and mating context of the experimental design.<\/jats:p>","DOI":"10.1093\/evolut\/qpag162","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:16:01Z","timestamp":1789672561000},"page":"2493-2505","source":"Crossref","is-referenced-by-count":0,"title":["Rapid male benefit adaptation in response to sex-limitation, mates, and genetic context in\n                    <i>Drosophila melanogaster<\/i>"],"prefix":"10.1093","volume":"80","author":[{"given":"Harshavardhan","family":"Thyagarajan","sequence":"first","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]},{"name":"Department of Biology, University of Fribourg , Fribourg ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mindy G","family":"Baroody","sequence":"additional","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]},{"name":"Department of Medicine, McMaster University , Niagara, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran","family":"Sayyed","sequence":"additional","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua A","family":"Kowal","sequence":"additional","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troy","family":"Day","sequence":"additional","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam K","family":"Chippindale","sequence":"additional","affiliation":[{"name":"Department of Biology, Queen\u2019s University , Kingston, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,19]]},"reference":[{"issue":"9","key":"2026110202565441700_bib1","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1111\/j.1420-9101.2010.02064.x","article-title":"Sexual conflict in wing size and shape in Drosophila melanogaster","volume":"23","author":"Abbott","year":"2010","journal-title":"Journal of Evolutionary Biology"},{"key":"2026110202565441700_bib2","doi-asserted-by":"publisher","first-page":"e70493","DOI":"10.1371\/journal.pone.0070493","article-title":"Epigenetics and sex-specific fitness: An experimental test using male-limited evolution in Drosophila melanogaster","volume":"8","author":"Abbott","year":"2013","journal-title":"PLoS ONE"},{"key":"2026110202565441700_bib3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting linear mixed-effects models using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"Journal of Statistical Software"},{"key":"2026110202565441700_bib4","doi-asserted-by":"publisher","first-page":"e2187","DOI":"10.1371\/journal.pone.0002187","article-title":"Reproductive behaviour evolves rapidly when intralocus sexual conflict is removed","volume":"3","author":"Bedhomme","year":"2008","journal-title":"PLoS ONE"},{"key":"2026110202565441700_bib5","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.tree.2008.12.005","article-title":"Intralocus sexual conflict","volume":"24","author":"Bonduriansky","year":"2009","journal-title":"Trends in Ecology & Evolution"},{"key":"2026110202565441700_bib6","first-page":"20172062","article-title":"Sex-specific adaptation and genomic responses to Y chromosome presence in female reproductive and neural tissues","volume-title":"Proceedings. 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