{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:56:24Z","timestamp":1753876584532,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Cleveland Clinic\u2019s Healthcare Delivery and Implementation Science Center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Identifying a window of opportunity when patients are motivated to lose weight might improve the effectiveness of weight loss counseling. The onset of chronic disease could create such a window.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To determine whether identifying prediabetes was associated with subsequent weight loss.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Our retrospective cohort study included adults with obesity and a primary care visit between 2015 and 2017. Data were collected and analysed in 2019\/2020. We compared patients who developed prediabetes [haemoglobin A1c (HbA1c) \u22655.7 and &amp;lt;6.5] to patients with a normal HbA1c (&amp;lt;5.7). We ran linear regression models to identify the association between identifying prediabetes and percent body mass index (BMI) change at 6 and 12 months. The adjusted model controlled for demographic characteristics at baseline, Charlson comorbidity score, and metformin, antipsychotic, antidepressant and antiobesity medication prescribed in either the first 3 months (for the 6-month outcome) or first 9 months (for 12-month outcome) and clustering within physician.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 11 290 participants, 43% developed prediabetes. At 6 months, 15% of the prediabetes group lost \u22655% of their BMI compared with 13% of the comparison group. The results were similar at 12 months with 18% of the prediabetes group losing \u22655% of their BMI compared with 17%. The prediabetes group lost a higher percentage of their BMI (\u03b2 = \u22120.7% versus \u22120.3% at 6 months and \u03b2 = \u22120.5% versus 0.01% at 12 months).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>While the percent of BMI change was small, patients with newly identified prediabetes lost more weight than a comparison group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/fampra\/cmab049","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T20:06:23Z","timestamp":1618257983000},"source":"Crossref","is-referenced-by-count":0,"title":["Do patients who have newly identified prediabetes lose weight in the following year?"],"prefix":"10.1093","author":[{"given":"Nayyer Homa","family":"Varghai","sequence":"first","affiliation":[{"name":"Department of Family Medicine, Cleveland Clinic, Beachwood, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael B","family":"Rothberg","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Community Care, Center for Value Based Care, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassandra","family":"Nathan","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Community Care, Center for Value Based Care, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3485-260X","authenticated-orcid":false,"given":"Elizabeth R","family":"Pfoh","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Community Care, Center for Value Based Care, Cleveland Clinic, Cleveland, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"issue":"1","key":"2021070818533087900_CIT0001","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.4102\/phcfm.v6i1.655","article-title":"Knowledge, attitude and practice regarding lifestyle modification in type 2 diabetic patients","volume":"6","author":"Okonta","year":"2014","journal-title":"Afr J Prim Health Care Fam Med"},{"issue":"10","key":"2021070818533087900_CIT0002","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1038\/oby.2006.209","article-title":"Television viewing and long-term weight maintenance: results from the National Weight Control Registry","volume":"14","author":"Raynor","year":"2006","journal-title":"Obesity (Silver Spring)"},{"key":"2021070818533087900_CIT0003","doi-asserted-by":"crossref","first-page":"w822","DOI":"10.1377\/hlthaff.28.5.w822","article-title":"Annual medical spending attributable to obesity: payer- and service-specific estimates: amid calls for health reform, real cost savings are more likely to be achieved through reducing obesity and related risk factors","volume":"28","author":"Finkelstein","year":"2009","journal-title":"Health Affairs"},{"issue":"2","key":"2021070818533087900_CIT0004","doi-asserted-by":"crossref","first-page":"e0191817","DOI":"10.1371\/journal.pone.0191817","article-title":"Patient-reported adherence to statin therapy, barriers to adherence, and perceptions of cardiovascular risk","volume":"13","author":"Fung","year":"2018","journal-title":"PLoS One"},{"issue":"4","key":"2021070818533087900_CIT0005","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.japh.2017.05.003","article-title":"Patient-reported reasons for nonadherence to recommended osteoporosis pharmacotherapy","volume":"57","author":"Hall","year":"2017","journal-title":"J Am Pharm Assoc 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