{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T16:47:39Z","timestamp":1762015659244,"version":"3.37.3"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"Supplement_1","license":[{"start":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T00:00:00Z","timestamp":1630022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>COVID-19 is an emergent infection, the long-term complications of which are still under study. While hypercoagulability is a common feature in severe cases, the incidence of ischemic complications such as osteonecrosis remains unknown. Previous studies on SARS-CoV1 found an increase in osteonecrosis 3\u201336 months after infection, and it is still unclear if this was related to the use of corticosteroids or to the virus itself.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We introduce a 78-year-old woman who complained of right knee pain and swelling a month after COVID-19 infection onset. Her knee radiography showed no significant changes compared to previous ones. MRI, on the other hand, found osteonecrosis in the internal femoral condyle. No coagulation abnormalities were found in blood tests.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>While knee replacement should be her main treatment, it will be long delayed due to the pandemic. In the meantime, we increased her tapentadol and salicylic acid doses and gave her home exercises to improve functionality.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In the follow-up after COVID-19, any muscular or joint pain with unusual characteristics should be carefully examined.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/fampra\/cmab063","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T20:12:37Z","timestamp":1622751157000},"page":"i45-i47","source":"Crossref","is-referenced-by-count":24,"title":["Knee osteonecrosis after COVID-19"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2171-2448","authenticated-orcid":false,"given":"Mar\u00eda","family":"Angulo-Ardoy","sequence":"first","affiliation":[{"name":"SERMAS, EAP Adelfas, M.P. Avenida Ciudad de Barcelona, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro","family":"Ure\u00f1a-Aguilera","sequence":"additional","affiliation":[{"name":"SERMAS, EAP Adelfas, M.P. Avenida Ciudad de Barcelona, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,27]]},"reference":[{"issue":"2","key":"2021082709443585200_CIT0001","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1302\/0301-620X.96B2.31935","article-title":"The influence of age, gender and treatment with steroids on the incidence of osteonecrosis of the femoral head during the management of severe acute respiratory syndrome: a retrospective study","volume":"96-B","author":"Guo","year":"2014","journal-title":"Bone Joint J"},{"issue":"6","key":"2021082709443585200_CIT0002","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00590-012-1054-4","article-title":"Osteonecrosis of the femoral head in SARS patients: seven years later","volume":"23","author":"Zhao","year":"2013","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"9","key":"2021082709443585200_CIT0003","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1097\/01.inf.0000137570.37856.ea","article-title":"Osteonecrosis in children with severe acute respiratory syndrome","volume":"23","author":"Chan","year":"2004","journal-title":"Pediatr Infect Dis J"},{"issue":"14","key":"2021082709443585200_CIT0004","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2106\/JBJS.20.00847","article-title":"Musculoskeletal consequences of COVID-19","volume":"102","author":"Disser","year":"2020","journal-title":"J Bone Joint Surg Am"},{"issue":"7","key":"2021082709443585200_CIT0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2106\/JBJS.RVW.20.00052","article-title":"Orthopaedic considerations following COVID-19: lessons from the 2003 sars outbreak","volume":"8","author":"Patel","year":"2020","journal-title":"JBJS Rev"},{"issue":"7","key":"2021082709443585200_CIT0006","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.crad.2003.12.008","article-title":"Avascular necrosis of bone in severe acute respiratory syndrome","volume":"59","author":"Hong","year":"2004","journal-title":"Clin Radiol"},{"issue":"10239","key":"2021082709443585200_CIT0007","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/S0140-6736(20)30749-2","article-title":"Caution against corticosteroid-based COVID-19 treatment","volume":"395","author":"Tang","year":"2020","journal-title":"Lancet"},{"issue":"6","key":"2021082709443585200_CIT0008","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1007\/s00134-020-06062-x","article-title":"High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study","volume":"46","author":"Helms","year":"2020","journal-title":"Intensive Care Med"},{"issue":"1","key":"2021082709443585200_CIT0009","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/s13054-020-02964-w","article-title":"Adjuvant corticosteroid therapy for critically ill patients with COVID-19","volume":"24","author":"Lu","year":"2020","journal-title":"Crit Care"},{"issue":"9","key":"2021082709443585200_CIT0010","doi-asserted-by":"crossref","first-page":"416","DOI":"10.5694\/mja2.50577","article-title":"Corticosteroid treatment of patients with coronavirus disease 2019 (COVID-19)","volume":"212","author":"Zha","year":"2020","journal-title":"Med J Aust"}],"container-title":["Family Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/fampra\/article-pdf\/38\/Supplement_1\/i45\/40037322\/cmab063.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/fampra\/article-pdf\/38\/Supplement_1\/i45\/40037322\/cmab063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T09:48:02Z","timestamp":1630057682000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/fampra\/article\/38\/Supplement_1\/i45\/6358429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,27]]},"references-count":10,"journal-issue":{"issue":"Supplement_1","published-online":{"date-parts":[[2021,8,27]]},"published-print":{"date-parts":[[2021,8,27]]}},"URL":"https:\/\/doi.org\/10.1093\/fampra\/cmab063","relation":{},"ISSN":["1460-2229"],"issn-type":[{"type":"electronic","value":"1460-2229"}],"subject":[],"published-other":{"date-parts":[[2021,9,1]]},"published":{"date-parts":[[2021,8,27]]}}}