{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:48:14Z","timestamp":1790934494676,"version":"4.1.0"},"reference-count":59,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007834","name":"Agricultural University of Athens","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007834","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013209","name":"HFRI","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013209","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Arbuscular mycorrhizal fungi (AMF) are plant symbionts that have a pivotal role in maintaining soil fertility and nutrient cycling. However, these microsymbionts may be exposed to organic pollutants like pesticides or veterinary drugs known to occur in agricultural soils. Anthelminthics are veterinary drugs that reach soils through the application of contaminated manures in agricultural settings. Their presence might threaten the function of AMF, considered as sensitive indicators of the toxicity of agrochemicals to the soil microbiota. We determined the impact of the anthelminthic compounds albendazole and ivermectin on the establishment and functionality of the symbiosis between the model-legume Lotus japonicus and the AMF Rhizophagus irregularis. Our analyses revealed negative effects of albendazole on the development and functionality of arbuscules, the symbiotic organelle of AMF, at a concentration of 0.75\u00a0\u03bcg g\u22121. The impairment of the symbiotic function was verified by the reduced expression of genes SbtM1, PT4 and AMT2;2 involved in arbuscules formation, P and N uptake, and the lower phosphorus shoot content detected in the albendazole-treated plants. Our results provide first evidence for the toxicity of albendazole on the colonization capacity and function of R. irregularis at concentrations that may occur in agricultural soils systematically amended with drug-containing manures.<\/jats:p>","DOI":"10.1093\/femsec\/fiad048","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T23:43:37Z","timestamp":1683589417000},"source":"Crossref","is-referenced-by-count":17,"title":["Veterinary drug albendazole inhibits root colonization and symbiotic function of the arbuscular mycorrhizal fungus <i>Rhizophagus irregularis<\/i>"],"prefix":"10.1093","volume":"99","author":[{"given":"Eleni","family":"Gkimprixi","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Biotechnology, University of Thessaly , Biopolis, 41500 Larissa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stathis","family":"Lagos","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biotechnology, University of Thessaly , Biopolis, 41500 Larissa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina N","family":"Nikolaou","sequence":"additional","affiliation":[{"name":"Department of Natural Resources and Agricultural Engineering, Agricultural University of Athens , 75 Iera Odos str., 11855 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios G","family":"Karpouzas","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biotechnology, University of Thessaly , Biopolis, 41500 Larissa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6295-4860","authenticated-orcid":false,"given":"Daniela","family":"Tsikou","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biotechnology, University of Thessaly , Biopolis, 41500 Larissa, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,5,8]]},"reference":[{"key":"2023120507045399200_bib1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12917-015-0442-5","article-title":"Comparative pharmacokinetics and bioavailability of albendazole sulfoxide in sheep and goats, and dose-dependent plasma disposition in goats","volume":"11","author":"Aksit","year":"2015","journal-title":"BMC Vet Res"},{"key":"2023120507045399200_bib2","first-page":"129","article-title":"Chapter 5 - Analysis of PhACs in Solid Environmental Samples (Soil, Sediment, and Sludge)","volume-title":"Comprehensive Analytical Chemistry","author":"Babi\u0107","year":"2013"},{"key":"2023120507045399200_bib3","doi-asserted-by":"crossref","first-page":"126658","DOI":"10.1016\/j.chemosphere.2020.126658","article-title":"Susceptibility of entomopathogenic nematodes to ivermectin and thiabendazole","volume":"253","author":"Barr\u00f3n-Bravo","year":"2020","journal-title":"Chemosphere"},{"key":"2023120507045399200_bib4","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.3389\/fpls.2019.01068","article-title":"Role of Arbuscular Mycorrhizal Fungi in Plant Growth Regulation: implications in Abiotic Stress Tolerance","volume":"10","author":"Begum","year":"2019","journal-title":"Front Plant Sci"},{"key":"2023120507045399200_bib5","doi-asserted-by":"crossref","first-page":"116106","DOI":"10.1016\/j.envpol.2020.116106","article-title":"Environmental risk assessment of the anthelmintic albendazole in Eastern Africa, based on a systematic review","volume":"269","author":"Belew","year":"2021","journal-title":"Environ Pollut"},{"key":"2023120507045399200_bib6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.envint.2015.09.013","article-title":"Ecotoxicological assessment of antibiotics: a call for improved consideration of microorganisms","volume":"85","author":"Brandt","year":"2015","journal-title":"Environ Int"},{"key":"2023120507045399200_bib7","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00572-014-0610-7","article-title":"Do fungicides used to control Rhizoctonia solani impact the non-target arbuscular mycorrhizal fungus Rhizophagus irregularis?","volume":"25","author":"Buysens","year":"2015","journal-title":"Mycorrhiza"},{"key":"2023120507045399200_bib8","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s00253-010-2649-5","article-title":"Effect of antibiotics in the environment on microbial populations","volume":"87","author":"Ding","year":"2010","journal-title":"Appl Microbiol Biotechnol"},{"key":"2023120507045399200_bib34","first-page":"e04690","article-title":"Scientific Opinion addressing the state of the science on risk assessment of plant protection products for in-soil organisms","volume":"15","author":"EFSA\u00a0Panel\u00a0on\u00a0Plant\u00a0Protection\u00a0Products\u00a0and\u00a0their\u00a0Residues\u00a0(PPR)","year":"2017","journal-title":"EFSA J"},{"key":"2023120507045399200_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/ffunb.2022.723892","article-title":"Roles of Arbuscular Mycorrhizal Fungi on Soil Fertility: contribution in the Improvement of Physical, Chemical, and Biological Properties of the Soil","volume":"3","author":"Fall","year":"2022","journal-title":"Front Fungal Biol"},{"key":"2023120507045399200_bib10","doi-asserted-by":"crossref","first-page":"e0126080","DOI":"10.1371\/journal.pone.0126080","article-title":"Pesticide Side Effects in an Agricultural Soil Ecosystem as Measured by amoA Expression Quantification and Bacterial Diversity Changes","volume":"10","author":"Feld","year":"2015","journal-title":"PLoS One"},{"key":"2023120507045399200_bib11","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1126\/science.1236281","article-title":"Evaluating Pesticide Degradation in the Environment: blind Spots and Emerging Opportunities","volume":"341","author":"Fenner","year":"2013","journal-title":"Science"},{"key":"2023120507045399200_bib12","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nrmicro.2017.87","article-title":"Embracing the unknown: disentangling the complexities of the soil microbiome","volume":"15","author":"Fierer","year":"2017","journal-title":"Nat Rev Microbiol"},{"key":"2023120507045399200_bib13","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1469-8137.1993.tb04537.x","article-title":"Factors affecting appressorium development in the vesicular\u2013arbuscular mycorrhizal fungus Glomus mosseae (Nicol. & Gerd.) Gerd. & Trappe","volume":"123","author":"Giovannetti","year":"1993","journal-title":"New Phytol"},{"key":"2023120507045399200_bib14","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1104\/pp.109.136390","article-title":"A mycorrhizal-specific ammonium transporter from Lotus japonicus acquires nitrogen released by arbuscular mycorrhizal fungi","volume":"150","author":"Guether","year":"2009","journal-title":"Plant Physiol"},{"key":"2023120507045399200_bib15","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/ps.5220","article-title":"Arbuscular mycorrhizal fungi and their response to pesticides","volume":"75","author":"Hage-Ahmed","year":"2019","journal-title":"Pest Manag Sci"},{"key":"2023120507045399200_bib16","article-title":"Sand and water culture methods used in the study of plant nutrition","volume-title":"Sand and Water Culture Methods Used in the Study of Plant Nutrition","author":"Hewitt","year":"1952"},{"key":"2023120507045399200_bib17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/nph.13445","article-title":"micro RNA 172 (miR172) signals epidermal infection and is expressed in cells primed for bacterial invasion in Lotus japonicus roots and nodules","volume":"208","author":"Holt","year":"2015","journal-title":"New Phytol"},{"key":"2023120507045399200_bib18","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1080\/03601234.2017.1371554","article-title":"Ivermectin dissipation and movement from feces to soil under field conditions","volume":"53","author":"Iglesias","year":"2018","journal-title":"J Environ Sci Health B"},{"key":"2023120507045399200_bib19","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.apsoil.2013.05.013","article-title":"Suppressive effects of seed-applied fungicides on arbuscular mycorrhizal fungi (AMF) differ with fungicide mode of action and AMF species","volume":"72","author":"Jin","year":"2013","journal-title":"Appl Soil Ecol"},{"key":"2023120507045399200_bib20","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cvfa.2019.12.001","article-title":"Biology, Epidemiology, Diagnosis, and Management of Anthelmintic Resistance in Gastrointestinal Nematodes of Livestock","volume":"36","author":"Kaplan","year":"2020","journal-title":"Vet Clin North Am Food Anim Pract"},{"key":"2023120507045399200_bib21","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ecolind.2013.12.004","article-title":"Effects of nicosulfuron on the abundance and diversity of arbuscular mycorrhizal fungi used as indicators of pesticide soil microbial toxicity","volume":"39","author":"Karpouzas","year":"2014","journal-title":"Ecol Indic"},{"key":"2023120507045399200_bib22","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1515\/pac-2022-0201","article-title":"Pesticide soil microbial toxicity: setting the scene for a new pesticide risk assessment for soil microorganisms (IUPAC Technical Report)","volume":"94","author":"Karpouzas","year":"2022","journal-title":"Pure Appl Chem"},{"key":"2023120507045399200_bib23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.watres.2014.12.041","article-title":"Chronic impact of tetracycline on nitrification kinetics and the activity of enriched nitrifying microbial culture","volume":"72","author":"Katipoglu-Yazan","year":"2015","journal-title":"Water Res"},{"key":"2023120507045399200_bib24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s005720050160","article-title":"Direct application of carbendazim and propiconazole at field rates to the external mycelium of three arbuscular mycorrhizal fungi species: effect on 32P transport and succinate dehydrogenase activity","volume":"7","author":"Kling","year":"1997","journal-title":"Mycorrhiza"},{"key":"2023120507045399200_bib25","doi-asserted-by":"crossref","first-page":"62404","DOI":"10.1007\/s11356-022-19964-8","article-title":"Biodegradation of anthelmintics in soils: does prior exposure of soils to anthelmintics accelerate their dissipation","volume":"29","author":"Lagos","year":"2022","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023120507045399200_bib26","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1469-8137.1996.tb04518.x","article-title":"Benomyl inhibits phosphorus transport but not fungal alkaline phosphatase activity in a Glomus-cucumber symbiosis","volume":"132","author":"Larsen","year":"1996","journal-title":"New Phytol"},{"key":"2023120507045399200_bib27","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/ieam.96","article-title":"Environmental risk assessment of ivermectin: a case study","volume":"6","author":"Liebig","year":"2010","journal-title":"Integr Environ Assess Manag"},{"key":"2023120507045399200_bib28","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s10646-018-1946-0","article-title":"Placing arbuscular mycorrhizal fungi on the risk assessment test battery of plant protection products (PPPs)","volume":"27","author":"Mallmann","year":"2018","journal-title":"Ecotoxicol"},{"key":"2023120507045399200_bib29","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.pt.2020.10.005","article-title":"Ivermectin: an Anthelmintic, an Insecticide, and Much More","volume":"37","author":"Martin","year":"2021","journal-title":"Trends Parasitol"},{"key":"2023120507045399200_bib30","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1007\/s11356-012-1368-0","article-title":"ECOFUN-MICROBIODIV: an FP7 European project for developing and evaluating innovative tools for assessing the impact of pesticides on soil functional microbial diversity\u2013towards new pesticide registration regulation?","volume":"20","author":"Martin-Laurent","year":"2013","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023120507045399200_bib31","doi-asserted-by":"crossref","first-page":"135692","DOI":"10.1016\/j.scitotenv.2019.135692","article-title":"Concentration and environmental fate of ivermectin in floodplain wetlands: an ecosystem approach","volume":"706","author":"Mesa","year":"2020","journal-title":"Sci Total Environ"},{"key":"2023120507045399200_bib32","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.chemosphere.2017.11.025","article-title":"Sorption of albendazole in sediments and soils: isotherms and kinetics","volume":"193","author":"Mutavd\u017ei\u0107\u00a0Pavlovi\u0107","year":"2018","journal-title":"Chemosphere"},{"key":"2023120507045399200_bib33","doi-asserted-by":"crossref","first-page":"117590","DOI":"10.1016\/j.envpol.2021.117590","article-title":"Proof of the environmental circulation of veterinary drug albendazole in real farm conditions","volume":"286","author":"Navr\u00e1tilov\u00e1","year":"2021","journal-title":"Environ Pollut"},{"key":"2023120507045399200_bib35","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1139\/W09-035","article-title":"the fate and efficacy of benomyl applied to field soils to suppress activity of arbuscular mycorrhizal fungi","volume":"55","author":"O'Connor","year":"2009","journal-title":"Can J Microbiol"},{"key":"2023120507045399200_bib36","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1007\/s00203-020-01915-x","article-title":"The potential of arbuscular mycorrhizal fungi in C cycling: a review","volume":"202","author":"Parihar","year":"2020","journal-title":"Arch Microbiol"},{"key":"2023120507045399200_bib37","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1469-8137.2006.01840.x","article-title":"a journey through signaling in arbuscular mycorrhizal symbioses 2006","volume":"172","author":"Paszkowski","year":"2006","journal-title":"New Phytol"},{"key":"2023120507045399200_bib38","doi-asserted-by":"crossref","first-page":"59040","DOI":"10.1007\/s11356-020-08389-w","article-title":"Leaching of benzimidazole antiparasitics in soil columns and in soil columns amended with sheep excreta","volume":"28","author":"Porto","year":"2021","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023120507045399200_bib39","doi-asserted-by":"crossref","first-page":"13015","DOI":"10.1007\/s11356-016-6472-0","article-title":"Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination","volume":"23","author":"Prchal","year":"2016","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023120507045399200_bib40","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0188-4409(01)00259-4","article-title":"In vitro effects of albendazole and its metabolites on the cell proliferation kinetics and micronuclei frequency of stimulated human lymphocytes","volume":"32","author":"Ram\u00edrez","year":"2001","journal-title":"Arch Med Res"},{"key":"2023120507045399200_bib41","doi-asserted-by":"crossref","first-page":"e00109","DOI":"10.1128\/AEM.00109-18","article-title":"Long-Term Exposure of Agricultural Soil to Veterinary Antibiotics Changes the Population Structure of Symbiotic Nitrogen-Fixing Rhizobacteria Occupying Nodules of Soybeans (Glycine max)","volume":"84","author":"Revellin","year":"2018","journal-title":"Appl Environ Microbiol"},{"key":"2023120507045399200_bib42","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1111\/nph.13045","article-title":"Plant root and mycorrhizal fungal traits for understanding soil aggregation","volume":"205","author":"Rillig","year":"2015","journal-title":"New Phytol"},{"key":"2023120507045399200_bib43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.scitotenv.2018.09.159","article-title":"Assessment of the ecotoxicological impact of natural and synthetic \u03b2-triketone herbicides on the diversity and activity of the soil bacterial community using omic approaches","volume":"651","author":"Romdhane","year":"2019","journal-title":"Sci Total Environ"},{"key":"2023120507045399200_bib44","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/gkp045","article-title":"Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data","volume":"37","author":"Ruijter","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"2023120507045399200_bib45","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1016\/S0038-0717(97)00259-9","article-title":"Dose\u2013response relationships between four pesticides and phosphorus uptake by hyphae of arbuscular mycorrhizas","volume":"30","author":"Schweiger","year":"1998","journal-title":"Soil Biol Biochem"},{"key":"2023120507045399200_bib46","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jhazmat.2013.01.007","article-title":"Evaluation of pharmaceuticals and personal care products with emphasis on anthelmintics in human sanitary waste, sewage, hospital wastewater, livestock wastewater and receiving water","volume":"248\u2013249","author":"Sim","year":"2013","journal-title":"J Hazard Mater"},{"key":"2023120507045399200_bib47","volume-title":"Mycorrhizal Symbiosis (Third Edition)","author":"Smith","year":"2008"},{"key":"2023120507045399200_bib48","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ecoenv.2017.03.014","article-title":"Evaluation of drug uptake and deactivation in plant: fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants","volume":"141","author":"Stuchl\u00edkov\u00e1\u00a0Raisov\u00e1","year":"2017","journal-title":"Ecotoxicol Environ Saf"},{"key":"2023120507045399200_bib49","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1469-8137.1993.tb03872.x","article-title":"the effect of fungicides on vesicular-arbuscular mycorrhizal symbiosis. I. The effects on vesicular-arbuscular mycorrhizal fungi and plant growth","volume":"125","author":"Sukarno","year":"1993","journal-title":"New Phytolog"},{"key":"2023120507045399200_bib50","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1002\/etc.5400","article-title":"Arbuscular mycorrhizal fungi and the need for a meaningful regulatory plant protection product testing strategy","volume":"41","author":"Sweeney","year":"2022","journal-title":"Environ Toxicol Chem"},{"key":"2023120507045399200_bib51","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/j.1365-313X.2009.03824.x","article-title":"Apoplastic plant subtilases support arbuscular mycorrhiza development in Lotus japonicus","volume":"58","author":"Takeda","year":"2009","journal-title":"Plant J"},{"key":"2023120507045399200_bib52","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/jpln.200390023","article-title":"Pharmaceutical antibiotic compounds in soils \u2013 a review","volume":"166","author":"Thiele-Bruhn","year":"2003","journal-title":"J Plant Nutr Soil Sci"},{"key":"2023120507045399200_bib53","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/s41579-020-0412-1","article-title":"Plant-microbiome interactions: from community assembly to plant health","volume":"18","author":"Trivedi","year":"2020","journal-title":"Nat Rev Microbiol"},{"key":"2023120507045399200_bib54","doi-asserted-by":"crossref","first-page":"e01536","DOI":"10.1128\/AEM.01536-18","article-title":"Blame It on the Metabolite: 3,5-Dichloroaniline Rather than the Parent Compound is Responsible for the Decreasing Diversity and Function of Soil Microorganisms","volume":"84","author":"Vasileiadis","year":"2018","journal-title":"Appl Environ Microbiol"},{"key":"2023120507045399200_bib55","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.scitotenv.2017.10.331","article-title":"Ivermectin residues disrupt dung beetle diversity, soil properties and ecosystem functioning: an interdisciplinary field study","volume":"618","author":"Verd\u00fa","year":"2018","journal-title":"Sci Total Environ"},{"key":"2023120507045399200_bib56","doi-asserted-by":"crossref","first-page":"5004","DOI":"10.1128\/AEM.64.12.5004-5007.1998","article-title":"Ink and vinegar, a simple staining technique for arbuscular-mycorrhizal fungi","volume":"64","author":"Vierheilig","year":"1998","journal-title":"Appl Environ Microbiol"},{"key":"2023120507045399200_bib57","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/pce.12659","article-title":"The phosphate transporters LjPT4 and MtPT4 mediate early root responses to phosphate status in non mycorrhizal roots","volume":"39","author":"Volpe","year":"2016","journal-title":"Plant Cell Environ"},{"key":"2023120507045399200_bib58","doi-asserted-by":"crossref","first-page":"e16949","DOI":"10.1371\/journal.pone.0016949","article-title":"noculations with Arbuscular Mycorrhizal Fungi Increase Vegetable Yields and Decrease Phoxim Concentrations in Carrot and Green Onion and Their Soils","volume":"6","author":"Wang","year":"2011","journal-title":"PLoS One"},{"key":"2023120507045399200_bib59","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.scitotenv.2019.02.240","article-title":"Using enzyme activities and soil microbial diversity to understand the effects of fluoxastrobin on microorganisms in fluvo-aquic soil","volume":"666","author":"Zhang","year":"2019","journal-title":"Sci Total Environ"}],"container-title":["FEMS Microbiology Ecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/femsec\/advance-article-pdf\/doi\/10.1093\/femsec\/fiad048\/50249163\/fiad048.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/femsec\/article-pdf\/99\/6\/fiad048\/53998415\/fiad048.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/femsec\/article-pdf\/99\/6\/fiad048\/53998415\/fiad048.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T07:05:51Z","timestamp":1701759951000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsec\/article\/doi\/10.1093\/femsec\/fiad048\/7157096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,8]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/femsec\/fiad048","relation":{},"ISSN":["1574-6941"],"issn-type":[{"value":"1574-6941","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,6]]},"published":{"date-parts":[[2023,5,8]]},"article-number":"fiad048"}}