{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:10:01Z","timestamp":1780319401667,"version":"3.54.1"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T00:00:00Z","timestamp":1581984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>There is a burgeoning literature highlighting differences in health outcomes between babies born vaginally and by caesarean section (c-section) This has led to the suggestion that infants born by c-section may benefit from vaginal swabbing\/seeding. Here, we discuss from an ecological perspective that it is gut-adapted, not vagina-adapted microbes that are likely to take up residence in the gut and have the most beneficial impact on the developing neonate. Further, we caution the practice of \u2018vaginal seeding\u2019 may be potentially unsafe and also give parents and health professionals a false sense of action in restoring the infant gut microbiome following c-section. Instead, we argue that restoring B. longum subsp. infantis, which has evolved to colonize the infant gut, is a safe and ecologically-sound approach to restoring the gut microbiome of infants born by c-section.<\/jats:p>","DOI":"10.1093\/femsle\/fnaa032","type":"journal-article","created":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T20:13:19Z","timestamp":1581970399000},"source":"Crossref","is-referenced-by-count":8,"title":["Reintroducing <i>B. infantis<\/i> to the cesarean-born neonate: an ecologically sound alternative to \u201cvaginal seeding\u201d"],"prefix":"10.1093","volume":"367","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2723-2237","authenticated-orcid":false,"given":"Rebbeca M","family":"Duar","sequence":"first","affiliation":[{"name":"Evolve BioSytems, Inc. Davis, California, 95618 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kyle","sequence":"additional","affiliation":[{"name":"Evolve BioSytems, Inc. Davis, California, 95618 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3675-9978","authenticated-orcid":false,"given":"Rachel M","family":"Tribe","sequence":"additional","affiliation":[{"name":"Dept. of Women and Children's Health, School of Life Course Sciences, St Thomas' Hospital, London SE1 7EH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,18]]},"reference":[{"key":"2022031804102364000_bib1","doi-asserted-by":"crossref","first-page":"e00164","DOI":"10.1128\/mSystems.00164-16","article-title":"Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling","volume":"2","author":"Asnicar","year":"2017","journal-title":"MSystems"},{"key":"2022031804102364000_bib2","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.chom.2015.04.004","article-title":"Dynamics and stabilization of the human gut microbiome during the first year of life","volume":"17","author":"Backhed","year":"2015","journal-title":"Cell Host Microbe"},{"key":"2022031804102364000_bib3","first-page":"1","article-title":"Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria","volume":"8","author":"Casaburi","year":"2019","journal-title":"Antimicrob Resist In Control"},{"key":"2022031804102364000_bib4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.humic.2018.05.001","article-title":"Colonization of breastfed infants by Bifidobacterium longum subsp. infantis EVC001 reduces virulence gene abundance","volume":"9","author":"Casaburi","year":"2018","journal-title":"Human Microbiome Journal"},{"key":"2022031804102364000_bib5","first-page":"e274","article-title":"Committee on Obstetric Practice. 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