{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T08:54:20Z","timestamp":1776502460523,"version":"3.51.2"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"14","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31700005"],"award-info":[{"award-number":["31700005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Campylobacter is a leading causative pathogen of acute bacterial gastroenteritis among humans. Contaminated chicken products are regarded as major sources of human infection. The flagellar capping protein (FliD), which plays important roles in colonization and adhesion to the mucosal surface of chicken ceca, is conserved among Campylobacter jejuni strains. In this study, the recombinant C. jejuni FliD protein was expressed, purified and used as a coated protein to examine the prevalence of C. jejuni antibodies in chickens. The anti-FliD antibody was prevalent among chicken serum samples taken from different farms in the diverse regions of Jiangsu province by using enzyme-linked immunosorbent assay. The Campylobacter antibody was present in culture-negative chickens. No strong dose\u2013response relationships were observed between serum FliD antibody levels and Campylobacter cultural status. These results provide a basis for further evaluating FliD as a vaccine candidate for broiler chickens or for examining host\u2013C. jejuni interactions, with implications for improving food safety.<\/jats:p>","DOI":"10.1093\/femsle\/fnaa115","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T11:30:29Z","timestamp":1594380629000},"source":"Crossref","is-referenced-by-count":6,"title":["Expression of the <i>Campylobacter jejuni<\/i> FliD protein and its reaction to chicken sera"],"prefix":"10.1093","volume":"367","author":[{"given":"Xiao-Yan","family":"Zhang","sequence":"first","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng-Jun","family":"Tang","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Hua","family":"Pu","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Feng","family":"Fan","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Xian","family":"Lu","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Lin","family":"Huang","sequence":"additional","affiliation":[{"name":"Jiangsu Key Lab of Zoonosis, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225003, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Shi","family":"Gao","sequence":"additional","affiliation":[{"name":"Jiangsu Institute of Poultry Sciences, Supervision, Inspection and Testing Centre for Poultry Quality (Yangzhou), Ministry of Agriculture, Yangzhou 225125, 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