{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T16:32:17Z","timestamp":1781195537365,"version":"3.54.1"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,29]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Free-living amoebae are known to act as replication niches for the pathogenic bacterium Legionella pneumophila in freshwater environments. However, we previously reported that some strains of the Willaertia magna species are more resistant to L. pneumophila infection and differ in their ability to support its growth. From this observation, we hypothesize that L. pneumophila growth in environment could be partly dependent on the composition of amoebic populations and on the possible interactions between different amoebic species. We tested this hypothesis by studying the growth of L. pneumophila and of a permissive free-living amoeba, Vermamoeba vermiformis (formerly named Hartmannella vermiformis), in co-culture with or without other free-living amoebae (Acanthamoeba castellanii and W. magna). We demonstrate the occurrence of inter-amoebic phagocytosis with A. castellanii and W. magna being able to ingest V. vermiformis infected or not infected with L. pneumophila. We also found that L. pneumophila growth is strongly impacted by the permissiveness of each interactive amoeba demonstrating that L. pneumophila proliferation and spread are controlled, at least in part, by inter-amoebic interactions.<\/jats:p>","DOI":"10.1093\/femsle\/fnaa147","type":"journal-article","created":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T11:11:43Z","timestamp":1598353903000},"source":"Crossref","is-referenced-by-count":5,"title":["Impact of inter-amoebic phagocytosis on the <i>L. pneumophila<\/i> growth"],"prefix":"10.1093","volume":"367","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4532-1751","authenticated-orcid":false,"given":"Rafik","family":"Dey","sequence":"first","affiliation":[{"name":"Universit\u00e9 claude Bernard Lyon I, 43 boulevard du 11 Novembre 1918, 69100 Villeurbanne, France"},{"name":"Universit\u00e9 Lyon 1; ISPB-Facult\u00e9 de Pharmacie Laboratoire de Biologie Cellulaire, 8, Avenue Rockefeller, F-69373, France"},{"name":"School of public health. University of Alberta, Edmonton AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouh Rayane","family":"Mameri","sequence":"additional","affiliation":[{"name":"Amoeba R & D Center, 38 Av des Fr\u00e8res Montgolfier, Chassieu F-69680, France"},{"name":"Universit\u00e9 Lyon 1; ISPB-Facult\u00e9 de Pharmacie Laboratoire de Biologie Cellulaire, 8, Avenue Rockefeller, F-69373, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selena","family":"Trajkovic-Bodennec","sequence":"additional","affiliation":[{"name":"Amoeba R & D Center, 38 Av des Fr\u00e8res Montgolfier, Chassieu F-69680, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Bodennec","sequence":"additional","affiliation":[{"name":"Universit\u00e9 claude Bernard Lyon I, 43 boulevard du 11 Novembre 1918, 69100 Villeurbanne, France"},{"name":"Universit\u00e9 Lyon 1, Lyon Neuroscience Research Center CNRS, UMR 5292, Villeurbanne, F-69622, France"},{"name":"Universit\u00e9 Lyon 1, INSERM, U1028, Tiger Team, Bron, F-69500, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Pernin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 claude Bernard Lyon I, 43 boulevard du 11 Novembre 1918, 69100 Villeurbanne, France"},{"name":"Universit\u00e9 Lyon 1; ISPB-Facult\u00e9 de Pharmacie Laboratoire de Biologie Cellulaire, 8, Avenue Rockefeller, F-69373, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,29]]},"reference":[{"key":"2022040814255941900_bib2","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1128\/iai.62.5.1860-1866.1994","article-title":"Protein expression by the protozoan Hartmannella vermiformis upon contact with its bacterial parasite Legionella pneumophila","volume":"62","author":"Abu\u00a0Kwaik","year":"1994","journal-title":"Infect 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