{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T08:38:00Z","timestamp":1783154280945,"version":"3.54.6"},"reference-count":63,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Salmonella remains the leading cause of foodborne infections globally. Environmental reservoirs, particularly aquatic bodies, serve as conduits for the fecal\u2013oral transmission of this pathogen. While the gastrointestinal tract is traditionally considered the primary habitat of Salmonella, mounting evidence suggests the bacterium\u2019s capacity for survival in external environments. The application of advanced technological platforms, such as next-generation sequencing, facilitates a comprehensive analysis of Salmonella\u2019s genomic features. This study aims to characterize the genomic composition of Salmonella isolates from river water, contributing to a potential paradigm shift and advancing public health protection. A total of 25 river water samples were collected and processed, followed by microbiological isolation of Salmonella strains, which were then sequenced. Genomic characterization revealed adaptive mechanisms, including gene duplication. Furthermore, an open pangenome, predisposed to incorporating foreign genetic material, was identified. Notably, antibiotic resistance genes were found to be part of the core genome, challenging previous reports that placed them in the accessory genome.<\/jats:p>","DOI":"10.1093\/femsle\/fnae090","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T11:48:44Z","timestamp":1731498524000},"source":"Crossref","is-referenced-by-count":3,"title":["The pangenome analysis of the environmental source <i>Salmonella enterica<\/i> highlights a diverse accessory genome and a distinct serotype clustering"],"prefix":"10.1093","volume":"371","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7378-0699","authenticated-orcid":false,"given":"Jos\u00e9 Roberto","family":"Aguirre-S\u00e1nchez","sequence":"first","affiliation":[{"name":"Laboratorio Nacional para la Investigaci\u00f3n en Inocuidad Alimentaria (LANIIA), Centro de Investigaci\u00f3n en Alimentaci\u00f3n y Desarrollo (CIAD). Culiac\u00e1n , Sinaloa , C.P. 80110,","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crist\u00f3bal","family":"Chaidez","sequence":"additional","affiliation":[{"name":"Laboratorio Nacional para la Investigaci\u00f3n en Inocuidad Alimentaria (LANIIA), Centro de Investigaci\u00f3n en Alimentaci\u00f3n y Desarrollo (CIAD). Culiac\u00e1n , Sinaloa , C.P. 80110,","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nohelia","family":"Castro-del\u00a0Campo","sequence":"additional","affiliation":[{"name":"Laboratorio Nacional para la Investigaci\u00f3n en Inocuidad Alimentaria (LANIIA), Centro de Investigaci\u00f3n en Alimentaci\u00f3n y Desarrollo (CIAD). Culiac\u00e1n , Sinaloa , C.P. 80110,","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"2024111915560865400_bib1","doi-asserted-by":"crossref","first-page":"e0007485","DOI":"10.1371\/journal.pntd.0007485","article-title":"Emergence of phylogenetically diverse and fluoroquinolone resistant Salmonella Enteritidis as a cause of invasive nontyphoidal Salmonella disease in Ghana","volume":"13","author":"Aldrich","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"2024111915560865400_bib2","author":"Andrews","year":"2017","journal-title":"FastQC: A Quality Control Tool for High Throughput Sequence Data 2010"},{"key":"2024111915560865400_bib4","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.cmi.2017.10.013","article-title":"Next-generation sequencing technologies and their application to the study and control of bacterial infections","volume":"24","author":"Besser","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"2024111915560865400_bib5","doi-asserted-by":"crossref","first-page":"100407","DOI":"10.1016\/j.hazadv.2024.100407","article-title":"Salmonella in the environment: a review on ecology, antimicrobial resistance, seafood contaminations, and human health implications","volume":"13","author":"Billah","year":"2024","journal-title":"J Hazard Mater Adv"},{"key":"2024111915560865400_bib6","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"2024111915560865400_bib7","first-page":"1","article-title":"Gene duplications in prokaryotes can be associated with environmental adaptation","volume":"11","author":"Bratlie","year":"2010","journal-title":"Bmc Genomics [Electronic Resource]"},{"key":"2024111915560865400_bib8","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1574-6968.2009.01697.x","article-title":"Identification and distribution of accessory genome DNA sequences from an invasive African isolate of Salmonella Heidelberg","volume":"298","author":"Bronowski","year":"2009","journal-title":"FEMS Microbiol Lett"},{"key":"2024111915560865400_bib9","doi-asserted-by":"crossref","first-page":"lxad034","DOI":"10.1093\/jambio\/lxad034","article-title":"Freshwater environment as a reservoir of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae","volume":"134","author":"Cho","year":"2023","journal-title":"J Appl Microbiol"},{"key":"2024111915560865400_bib10","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1099\/ijsem.0.002809","article-title":"Using average nucleotide identity to improve taxonomic assignments in prokaryotic genomes at the NCBI","volume":"68","author":"Ciufo","year":"2018","journal-title":"Int J Syst Evol Microbiol"},{"key":"2024111915560865400_bib11","doi-asserted-by":"crossref","first-page":"1005215","DOI":"10.3389\/fmicb.2022.1005215","article-title":"Salmonella enterica serovar Cerro displays a phylogenetic structure and genomic features consistent with virulence attenuation and adaptation to cattle","volume":"13","author":"Cohn","year":"2022","journal-title":"Front Microbiol"},{"key":"2024111915560865400_bib12","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1093\/bioinformatics\/btu661","article-title":"A5-miseq: an updated pipeline to assemble microbial genomes from Illumina MiSeq data","volume":"31","author":"Coil","year":"2015","journal-title":"Bioinformatics"},{"key":"2024111915560865400_bib13","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nbt.3423","article-title":"Three decades of nanopore sequencing","volume":"34","author":"Deamer","year":"2016","journal-title":"Nat Biotechnol"},{"key":"2024111915560865400_bib14","doi-asserted-by":"crossref","first-page":"e4320","DOI":"10.7717\/peerj.4320","article-title":"Linking pangenomes and metagenomes: the prochlorococcus metapangenome","volume":"6","author":"Delmont","year":"2018","journal-title":"PeerJ"},{"key":"2024111915560865400_bib15","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/S1369-5274(00)00250-2","article-title":"Whole genome plasticity in pathogenic bacteria","volume":"4","author":"Dobrindt","year":"2001","journal-title":"Curr Opin Microbiol"},{"key":"2024111915560865400_bib16","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/s41559-023-02268-6","article-title":"Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes","volume":"8","author":"Douglas","year":"2024","journal-title":"Nat Ecol Evol"},{"key":"2024111915560865400_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13059-019-1832-y","article-title":"OrthoFinder: phylogenetic orthology inference for comparative genomics","volume":"20","author":"Emms","year":"2019","journal-title":"Genome Biol"},{"key":"2024111915560865400_bib18","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1080\/21553769.2015.1051243","article-title":"Salmonella: a review on pathogenesis, epidemiology and antibiotic resistance","volume":"8","author":"Eng","year":"2015","journal-title":"Front Life Sci"},{"key":"2024111915560865400_bib19","doi-asserted-by":"crossref","first-page":"e1319","DOI":"10.7717\/peerj.1319","article-title":"Anvi'o: an advanced analysis and visualization platform for \u2018omics data","volume":"3","author":"Eren","year":"2015","journal-title":"PeerJ"},{"key":"2024111915560865400_bib3","first-page":"e07666","article-title":"The European Union One Health 2021 Zoonoses Report","volume":"20","author":"European Food Safety Authority, European Centre for Disease Prevention and Control","year":"2022","journal-title":"EFSA J"},{"key":"2024111915560865400_bib20","doi-asserted-by":"crossref","first-page":"104446","DOI":"10.1016\/j.meegid.2020.104446","article-title":"A bioinformatic approach to identify core genome difference between Salmonella Pullorum and Salmonella Enteritidis","volume":"85","author":"Fei","year":"2020","journal-title":"Infect Genet Evol"},{"key":"2024111915560865400_bib21","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1093\/gbe\/evz158","article-title":"Geography shapes the population genomics of Salmonella enterica Dublin","volume":"11","author":"Fenske","year":"2019","journal-title":"Genome Biol Evolut"},{"key":"2024111915560865400_bib22","first-page":"84","article-title":"Genome plasticity in Salmonella enterica and its relevance to host-pathogen interactions","volume-title":"Genome Plasticity and Infectious Diseases","author":"Ferreira","year":"2012"},{"key":"2024111915560865400_bib23","doi-asserted-by":"crossref","first-page":"e00332","DOI":"10.1128\/Spectrum.00332-21","article-title":"Epidemiological analysis of Salmonella enterica subsp. Enterica Serovar Dublin in German cattle herds using whole-genome sequencing","volume":"9","author":"Garc\u00eda-Soto","year":"2021","journal-title":"Microbiol Spectr"},{"key":"2024111915560865400_bib24","doi-asserted-by":"crossref","first-page":"e1007732","DOI":"10.1371\/journal.pcbi.1007732","article-title":"PPanGGOLiN: depicting microbial diversity via a partitioned pangenome graph","volume":"16","author":"Gautreau","year":"2020","journal-title":"PLoS Comput Biol"},{"key":"2024111915560865400_bib25","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1017\/S0950268816001941","article-title":"Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak of Salmonella Enteritidis","volume":"145","author":"Inns","year":"2017","journal-title":"Epidemiology & Infection"},{"key":"2024111915560865400_bib26","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s00248-011-9880-1","article-title":"The Salmonella enterica pan-genome","volume":"62","author":"Jacobsen","year":"2011","journal-title":"Microb Ecol"},{"key":"2024111915560865400_bib27","doi-asserted-by":"crossref","first-page":"504","DOI":"10.14202\/vetworld.2019.504-521","article-title":"A review of Salmonella enterica with particular focus on the pathogenicity and virulence factors, host specificity and antimicrobial resistance including multidrug resistance","volume":"12","author":"Jajere","year":"2019","journal-title":"Veterinary World"},{"key":"2024111915560865400_bib28","doi-asserted-by":"crossref","first-page":"8299","DOI":"10.1038\/s41598-020-64934-0","article-title":"Genomic profiling of antimicrobial resistance genes in clinical isolates of Salmonella Typhi from patients infected with Typhoid fever in India","volume":"10","author":"Katiyar","year":"2020","journal-title":"Sci Rep"},{"key":"2024111915560865400_bib29","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s43141-023-00591-w","article-title":"Pangenome diversification and resistance gene characterization in Salmonella Typhi prioritized RfaJ as a significant therapeutic marker","volume":"21","author":"Khan","year":"2023","journal-title":"J Genetic Engineering Biotechnol"},{"key":"2024111915560865400_bib31","doi-asserted-by":"crossref","first-page":"5048","DOI":"10.1098\/rspb.2012.1108","article-title":"Gene duplication as a mechanism of genomic adaptation to a changing environment","volume":"279","author":"Kondrashov","year":"2012","journal-title":"Proc R Soc B Biol Sci"},{"key":"2024111915560865400_bib32","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1093\/gbe\/evw105","article-title":"Antibiotic resistance, core-genome and protein expression in IncHI1 plasmids in Salmonella Typhimurium","volume":"8","author":"Kubasova","year":"2016","journal-title":"Genome Biol Evolut"},{"key":"2024111915560865400_bib33","first-page":"199","article-title":"Whole genome sequencing in clinical and public health microbiology","volume":"47","author":"Kwong","year":"2015","journal-title":"Pathology (Phila)"},{"key":"2024111915560865400_bib34","doi-asserted-by":"crossref","first-page":"261886","DOI":"10.3389\/fmicb.2017.01345","article-title":"Pan-genome analyses of the species Salmonella enterica, and identification of genomic markers predictive for species, subspecies, and serovar","volume":"8","author":"Laing","year":"2017","journal-title":"Front Microbiol"},{"key":"2024111915560865400_bib35","doi-asserted-by":"crossref","first-page":"1254777","DOI":"10.3389\/fmicb.2023.1254777","article-title":"Evaluation of whole and core genome multilocus sequence typing allele schemes for Salmonella enterica outbreak detection in a national surveillance network, PulseNet USA","volume":"14","author":"Leeper","year":"2023","journal-title":"Front Microbiol"},{"key":"2024111915560865400_bib36","doi-asserted-by":"publisher","first-page":"W256","DOI":"10.1093\/nar\/gkz239","article-title":"Interactive Tree of Life (iTOL) v4: recent updates and new developments","volume":"47","author":"Letunic","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"2024111915560865400_bib37","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.foodres.2011.06.037","article-title":"Salmonella in surface and drinking water: occurrence and water-mediated transmission","volume":"45","author":"Levantesi","year":"2012","journal-title":"Food Res Int"},{"key":"2024111915560865400_bib38","first-page":"1","article-title":"Analysis of isolates from Bangladesh highlights multiple ways to carry resistance genes in Salmonella Typhi","volume":"20","author":"Lima","year":"2019","journal-title":"Bmc Genomics [Electronic Resource]"},{"key":"2024111915560865400_bib39","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3390\/tropicalmed4020088","article-title":"The one health approach\u2014Why is it so important?","volume":"4","author":"Mackenzie","year":"2019","journal-title":"Tropical Medicine and Infectious Disease"},{"key":"2024111915560865400_bib40","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.tim.2013.11.001","article-title":"The role of aquatic ecosystems as reservoirs of antibiotic resistance","volume":"22","author":"Marti","year":"2014","journal-title":"Trends Microbiol"},{"key":"2024111915560865400_bib42","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrg2626","article-title":"Sequencing technologies\u2014The next generation","volume":"11","author":"Metzker","year":"2010","journal-title":"Nat Rev Genet"},{"key":"2024111915560865400_bib43","doi-asserted-by":"crossref","first-page":"103991","DOI":"10.1016\/j.resmic.2022.103991","article-title":"Phenotypic impacts and genetic regulation characteristics of the DNA adenine methylase gene (dam) in Salmonella Typhimurium biofilm forms","volume":"174","author":"O\u011fuz","year":"2023","journal-title":"Res Microbiol"},{"key":"2024111915560865400_bib44","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1093\/bioinformatics\/btv421","article-title":"Roary: rapid large-scale prokaryote pan genome analysis","volume":"31","author":"Page","year":"2015","journal-title":"Bioinformatics"},{"key":"2024111915560865400_bib45","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1016\/j.ygeno.2021.07.003","article-title":"An evaluation of the species and subspecies of the genus Salmonella with whole genome sequence data: proposal of type strains and epithets for novel S. enterica subspecies VII, VIII, IX, X and XI","volume":"113","author":"Pearce","year":"2021","journal-title":"Genomics"},{"key":"2024111915560865400_bib46","doi-asserted-by":"crossref","first-page":"6881","DOI":"10.1128\/JB.00619-08","article-title":"The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates","volume":"190","author":"Rasko","year":"2008","journal-title":"J Bacteriol"},{"key":"2024111915560865400_bib47","doi-asserted-by":"crossref","first-page":"6465","DOI":"10.1128\/JB.00969-10","article-title":"Evolution and population structure of Salmonella enterica serovar Newport","volume":"192","author":"Sangal","year":"2010","journal-title":"J Bacteriol"},{"key":"2024111915560865400_bib48","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1093\/bioinformatics\/btu153","article-title":"Prokka: rapid prokaryotic genome annotation","volume":"30","author":"Seemann","year":"2014","journal-title":"Bioinformatics"},{"key":"2024111915560865400_bib49","volume-title":"mlst","author":"Seemann","year":"2022"},{"key":"2024111915560865400_bib50","doi-asserted-by":"crossref","first-page":"eabe3868","DOI":"10.1126\/sciadv.abe3868","article-title":"Niche and local geography shape the pangenome of wastewater-and livestock-associated Enterobacteriaceae","volume":"7","author":"Shaw","year":"2021","journal-title":"Sci Adv"},{"key":"2024111915560865400_bib51","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.foodres.2011.06.056","article-title":"Resistance and survival strategies of Salmonella enterica to environmental stresses","volume":"45","author":"Spector","year":"2012","journal-title":"Food Res Int"},{"key":"2024111915560865400_bib52","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.4315\/0362-028X-67.12.2839","article-title":"Irrigation water as source of foodborne pathogens on fruit and vegetables","volume":"67","author":"Steele","year":"2004","journal-title":"J Food Prot"},{"key":"2024111915560865400_bib53","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1128\/IAI.74.1.632-644.2006","article-title":"Virulence of broad-and narrow-host-range salmonella enterica serovars in the Streptomycin-pretreatedmouse model","volume":"74","author":"Suar","year":"2006","journal-title":"Infect Immun"},{"key":"2024111915560865400_bib54","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.mib.2008.09.006","article-title":"Comparative genomics: the bacterial pan-genome","volume":"11","author":"Tettelin","year":"2008","journal-title":"Curr Opin Microbiol"},{"key":"2024111915560865400_bib55","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/nrmicro1234","article-title":"Mechanisms of, and barriers to, horizontal gene transfer between bacteria","volume":"3","author":"Thomas","year":"2005","journal-title":"Nat Rev Microbiol"},{"key":"2024111915560865400_bib56","doi-asserted-by":"crossref","first-page":"e0255612","DOI":"10.1371\/journal.pone.0255612","article-title":"Comparative genome analysis of Salmonella enterica serovar gallinarum biovars Pullorum and Gallinarum decodes strain specific genes","volume":"16","author":"Vaid","year":"2021","journal-title":"PLoS One"},{"key":"2024111915560865400_bib57","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.mib.2014.11.016","article-title":"Ten years of pan-genome analyses","volume":"23","author":"Vernikos","year":"2015","journal-title":"Curr Opin Microbiol"},{"key":"2024111915560865400_bib58","doi-asserted-by":"publisher","first-page":"128","DOI":"10.3390\/pathogens1020128","article-title":"From exit to entry: long-term survival and transmission of Salmonella","volume":"1","author":"Waldner","year":"2012","journal-title":"Pathogens"},{"key":"2024111915560865400_bib59","doi-asserted-by":"crossref","first-page":"119603","DOI":"10.1016\/j.envpol.2022.119603","article-title":"Role of environmental stresses in elevating resistance mutations in bacteria: phenomena and mechanisms","volume":"307","author":"Wang","year":"2022","journal-title":"Environ Pollut"},{"key":"2024111915560865400_bib60","volume-title":"Salmonella (non-typhoidal)","author":"WHO","year":"2018"},{"key":"2024111915560865400_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/gb-2007-8-12-r267","article-title":"Characterization of probiotic Escherichia coli isolates with a novel pan-genome microarray","volume":"8","author":"Willenbrock","year":"2007","journal-title":"Genome Biol"},{"key":"2024111915560865400_bib62","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/mBio.02303-18","article-title":"Salmonella enterica phylogeny based on whole-genome sequencing reveals two new clades and novel patterns of horizontally acquired genetic elements","volume":"9","author":"Worley","year":"2018","journal-title":"mBio"},{"key":"2024111915560865400_bib63","doi-asserted-by":"crossref","first-page":"5226","DOI":"10.3390\/ijms21155226","article-title":"Whole-genome-based survey for polyphyletic serovars of Salmonella enterica subsp. Enterica provides new insights into public health surveillance","volume":"21","author":"Yin","year":"2020","journal-title":"Int J Mol Sci"},{"key":"2024111915560865400_bib64","doi-asserted-by":"crossref","first-page":"e0147101","DOI":"10.1371\/journal.pone.0147101","article-title":"The Salmonella in silico typing resource (SISTR): an open web-accessible tool for rapidly typing and subtyping draft Salmonella genome assemblies","volume":"11","author":"Yoshida","year":"2016","journal-title":"PLoS One"},{"key":"2024111915560865400_bib65","doi-asserted-by":"crossref","first-page":"e1003471","DOI":"10.1371\/journal.pgen.1003471","article-title":"Neutral genomic microevolution of a recently emerged pathogen, Salmonella enterica serovar Agona","volume":"9","author":"Zhou","year":"2013","journal-title":"PLos Genet"}],"container-title":["FEMS Microbiology Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/femsle\/advance-article-pdf\/doi\/10.1093\/femsle\/fnae090\/60630600\/fnae090.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/femsle\/article-pdf\/doi\/10.1093\/femsle\/fnae090\/60750603\/fnae090.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/femsle\/article-pdf\/doi\/10.1093\/femsle\/fnae090\/60750603\/fnae090.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T15:59:42Z","timestamp":1732031982000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsle\/article\/doi\/10.1093\/femsle\/fnae090\/7896413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":63,"URL":"https:\/\/doi.org\/10.1093\/femsle\/fnae090","relation":{},"ISSN":["1574-6968"],"issn-type":[{"value":"1574-6968","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024]]},"published":{"date-parts":[[2024]]},"article-number":"fnae090"}}