{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:09:54Z","timestamp":1780758594029,"version":"3.54.1"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"20","funder":[{"DOI":"10.13039\/100000199","name":"United States Department of Agriculture","doi-asserted-by":"publisher","award":["2011-2012-67017-30218"],"award-info":[{"award-number":["2011-2012-67017-30218"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,1]]},"DOI":"10.1093\/femsle\/fnx207","type":"journal-article","created":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T15:12:01Z","timestamp":1506438721000},"source":"Crossref","is-referenced-by-count":11,"title":["Penicillin-binding protein encoded by pbp4 is involved in mediating copper stress in Listeria monocytogenes"],"prefix":"10.1093","volume":"364","author":[{"given":"Cameron","family":"Parsons","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Costolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Kathariou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,10,4]]},"reference":[{"key":"key\n\t\t\t\t20180215000751_bib1","article-title":"Impact of manganese, copper and zinc ions on the transcriptome of the nosocomial pathogen Enterococcus faecalis V583","volume":"6","author":"Abrantes","year":"2011","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180215000751_bib2","doi-asserted-by":"crossref","first-page":"6998","DOI":"10.1128\/AEM.01223-10","article-title":"Temperature-dependent requirement for catalase in aerobic growth of Listeria monocytogenes F2365","volume":"76","author":"Azizoglu","year":"2010","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib3","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.jmb.2005.11.055","article-title":"Structural basis for metal binding specificity: the N-terminal cadmium binding domain of the P1-type ATPase CadA","volume":"356","author":"Banci","year":"2006","journal-title":"J Mol Biol"},{"key":"key\n\t\t\t\t20180215000751_bib4","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1128\/AEM.72.3.2231-2234.2006","article-title":"Tolerance of Listeria monocytogenes to cell envelope-acting antimicrobial agents is dependent on SigB","volume":"72","author":"Begley","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib6","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1128\/JCM.01874-13","article-title":"\u201cEpidemic clones\u201d of Listeria monocytogenes are widespread and ancient clonal groups","volume":"51","author":"Cantinelli","year":"2013","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2011.01.005","article-title":"Review\u2014persistence of Listeria monocytogenes in food industry equipment and premises","volume":"145","author":"Carpentier","year":"2011","journal-title":"Int J Food Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib8","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1128\/AEM.02844-06","article-title":"A mariner-based transposition system for Listeria monocytogenes","volume":"73","author":"Cao","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib9","doi-asserted-by":"crossref","first-page":"19204","DOI":"10.1074\/jbc.M114.556704","article-title":"Cu(I)-mediated allosteric switching in a copper-sensing operon repressor (CsoR)","volume":"289","author":"Chang","year":"2014","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20180215000751_bib10","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1007\/s00253-011-3719-z","article-title":"Identification of genes involved in Listeria monocytogenes biofilm formation by mariner-based transposon mutagenesis","volume":"93","author":"Chang","year":"2012","journal-title":"Appl Microbiol Biotechnol"},{"key":"key\n\t\t\t\t20180215000751_bib11","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S1473-3099(16)30521-7","article-title":"Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study","volume":"17","author":"Charlier","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"key\n\t\t\t\t20180215000751_bib13","doi-asserted-by":"crossref","first-page":"6258","DOI":"10.1128\/AEM.01532-16","article-title":"Core genome multilocus sequence typing for identification of globally distributed clonal groups and differentiation of outbreak strains of Listeria monocytogenes","volume":"82","author":"Chen","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib14","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1128\/AEM.07402-11","article-title":"Assessing the contributions of the LiaS histidine kinase to the innate resistance of Listeria monocytogenes to nisin, cephalosporins, and disinfectants","volume":"78","author":"Collins","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib15","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1365-2958.2011.07705.x","article-title":"The combined actions of the copper-responsive repressor CsoR and copper-metallochaperone CopZ modulate CopA-mediated copper efflux in the intracellular pathogen Listeria monocytogenes","volume":"81","author":"Corbett","year":"2011","journal-title":"Mol Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib16","doi-asserted-by":"crossref","first-page":"5379","DOI":"10.1128\/AEM.01398-14","article-title":"Genetic characterization of plasmid-associated triphenylmethane reductase in Listeria monocytogenes","volume":"80","author":"Dutta","year":"2014","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/mpat.1996.0092","article-title":"Mutants in the CtpA copper transporting P-type ATPase reduce virulence of Listeria monocytogenes","volume":"22","author":"Francis","year":"1997","journal-title":"Microb Pathog"},{"key":"key\n\t\t\t\t20180215000751_bib18","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrmicro2171","article-title":"Listeria monocytogenes\u2014from saprophyte to intracellular pathogen","volume":"7","author":"Freitag","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2006.07.008","article-title":"Listeria: a foodborne pathogen that knows how to survive","volume":"113","author":"Gandhi","year":"2007","journal-title":"Int J Food Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.4315\/0362-028X.JFP-15-387","article-title":"Fresh produce-associated listeriosis outbreaks, sources of concern, teachable moments, and insights","volume":"79","author":"Garner","year":"2016","journal-title":"J Food Prot"},{"key":"key\n\t\t\t\t20180215000751_bib21","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1128\/AEM.70.3.1669-1679.2004","article-title":"pbp2229-mediated nisin resistance mechanism in Listeria monocytogenes confers cross-protection to class IIa bacteriocins and affects virulence gene expression","volume":"70","author":"Gravesen","year":"2004","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib22","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1128\/AAC.00167-06","article-title":"Contribution of penicillin-binding protein homologs to antibiotic resistance, cell morphology, and virulence of Listeria monocytogenes EGDe","volume":"50","author":"Guinane","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t20180215000751_bib23","doi-asserted-by":"crossref","first-page":"5784","DOI":"10.1128\/AEM.02979-05","article-title":"Copper resistance in Enterococcus faecium, mediated by the tcrB gene, is selected by supplementation of pig feed with copper sulfate","volume":"72","author":"Hasman","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib24","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/mmi.12422","article-title":"Coordinate synthesis and protein localization in a bacterial organelle by the action of a penicillin-binding-protein","volume":"90","author":"Hughes","year":"2013","journal-title":"Mol Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib25","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/bs.ampbs.2014.08.003","article-title":"Metal ion homeostasis in Listeria monocytogenes and importance in host-pathogen interactions","volume":"65","author":"Jesse","year":"2014","journal-title":"Adv Microb Physiol"},{"key":"key\n\t\t\t\t20180215000751_bib27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1186\/1471-2180-10-239","article-title":"Identification of the full set of Listeria monocytogenes penicillin-binding proteins and characterization of PBPD2 (Lmo2812)","volume":"10","author":"Korsak","year":"2010","journal-title":"BMC Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1471-2180-12-57","article-title":"Re-evaluation of the significance of penicillin binding protein 3 in the susceptibility of Listeria monocytogenes to \u03b2-lactam antibiotics","volume":"12","author":"Krawczyk-Balska","year":"2012","journal-title":"BMC Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0012511","article-title":"Comparative analysis of plasmids in the genus Listeria","volume":"5","author":"Kuenne","year":"2010","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180215000751_bib30","doi-asserted-by":"crossref","first-page":"4177","DOI":"10.1128\/JB.184.15.4177-4186.2002","article-title":"Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors","volume":"184","author":"Lauer","year":"2002","journal-title":"J Bacteriol"},{"key":"key\n\t\t\t\t20180215000751_bib31","doi-asserted-by":"crossref","first-page":"757","DOI":"10.4315\/0362-028X.JFP-15-498","article-title":"Capacity of Listeria monocytogenes strains from the 2011 cantaloupe outbreak to adhere, survive, and grow on cantaloupe","volume":"79","author":"Martinez","year":"2016","journal-title":"J Food Prot"},{"key":"key\n\t\t\t\t20180215000751_bib32","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1056\/NEJMoa1215837","article-title":"Multistate outbreak of listeriosis associated with cantaloupe","volume":"369","author":"McCollum","year":"2013","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180215000751_bib33","article-title":"Copper alloys for human infectious disease control","volume":"11","author":"Michels","year":"2005","journal-title":"Proceedings of the Materials Science and Technology Conference, Pittsburgh, PA. Copper for the 21st Century Symposium"},{"key":"key\n\t\t\t\t20180215000751_bib34","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1007\/s00253-010-2640-1","article-title":"Survival of bacteria on metallic copper surfaces in a hospital trial","volume":"87","author":"Mikolay","year":"2010","journal-title":"Appl Microbiol Biotechnol"},{"key":"key\n\t\t\t\t20180215000751_bib35","doi-asserted-by":"crossref","first-page":"16185","DOI":"10.1038\/nmicrobiol.2016.185","article-title":"Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes","volume":"2","author":"Moura","year":"2016","journal-title":"Nat Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib36","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1128\/MMBR.67.4.686-723.2003","article-title":"A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria","volume":"67","author":"Neuhaus","year":"2003","journal-title":"Microbiol Mol Biol Rev"},{"key":"key\n\t\t\t\t20180215000751_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femsec\/fiw175","article-title":"Coping with copper: legacy effect of copper on potential activity of soil bacteria following a century of exposure","volume":"92","author":"Nunes","year":"2016","journal-title":"FEMS Microbiol Ecol"},{"key":"key\n\t\t\t\t20180215000751_bib40","doi-asserted-by":"crossref","first-page":"e02580","DOI":"10.1128\/AEM.02580-16","article-title":"Novel cadmium resistance determinant in Listeria monocytogenes","volume":"83","author":"Parsons","year":"2017","journal-title":"Appl Environ Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib41","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/mmi.12873","article-title":"Discrete and overlapping functions of peptidoglycan synthases in growth, cell division and virulence of Listeria monocytogenes","volume":"95","author":"Rismondo","year":"2015","journal-title":"Mol Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib42","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.chom.2012.01.009","article-title":"Copper in microbial pathogenesis: meddling with the metal","volume":"11","author":"Samanovic","year":"2012","journal-title":"Cell Host Microbe"},{"key":"key\n\t\t\t\t20180215000751_bib44","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mimet.2015.01.011","article-title":"Proteome mining for drug target identification in Listeria monocytogenes strain EGD-e and structure-based virtual screening of a candidate drug target penicillin binding protein 4","volume":"111","author":"Sarangi","year":"2015","journal-title":"J Microbiol Methods"},{"key":"key\n\t\t\t\t20180215000751_bib45","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3201\/eid1701.P11101","article-title":"Foodborne illness acquired in the United States\u2014major pathogens","volume":"17","author":"Scallan","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"key\n\t\t\t\t20180215000751_bib46","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1038\/nbt1183-784","article-title":"A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria","volume":"1","author":"Simon","year":"1983","journal-title":"Nat Biotechnol"},{"key":"key\n\t\t\t\t20180215000751_bib47","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1128\/JB.02433-14","article-title":"The copYAZ operon functions in copper efflux, biofilm Formation, genetic transformation, and stress tolerance in Streptococcus mutans","volume":"197","author":"Singh","year":"2015","journal-title":"J Bacteriol"},{"key":"key\n\t\t\t\t20180215000751_bib48","article-title":"Technical evaluation report copper sulfate","author":"United States Department of Agriculture","year":"2015"},{"key":"key\n\t\t\t\t20180215000751_bib49","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3389\/fcimb.2013.00087","article-title":"Listeria monocytogenes, a down-to-earth pathogen","volume":"3","author":"Vivant","year":"2013","journal-title":"Front Cell Infect Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib50","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/nrmicro2057","article-title":"How do bacterial cells ensure that metalloproteins get the correct metal?","volume":"7","author":"Waldron","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib51","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijfoodmicro.2006.04.037","article-title":"Survival of Listeria monocytogenes Scott A on metal surfaces: implications for cross-contamination","volume":"111","author":"Wilks","year":"2006","journal-title":"Int J Food Microbiol"},{"key":"key\n\t\t\t\t20180215000751_bib52","doi-asserted-by":"crossref","first-page":"5569","DOI":"10.1007\/s00253-016-7361-7","article-title":"Understanding the antimicrobial activity behind thin- and thick-rolled copper plates","volume":"100","author":"Yousuf","year":"2016","journal-title":"Appl Microbiol Biotechnol"},{"key":"key\n\t\t\t\t20180215000751_bib53","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1128\/JB.188.5.1875-1881.2006","article-title":"Characterization of the bifunctional glycosyltransferase\/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes","volume":"188","author":"Zawadzka-Skomial","year":"2006","journal-title":"J Bacteriol"}],"container-title":["FEMS Microbiology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femsle\/article-pdf\/364\/20\/fnx207\/23930566\/fnx207.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T00:09:11Z","timestamp":1518653351000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsle\/article\/doi\/10.1093\/femsle\/fnx207\/4329268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":47,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2017,10,4]]},"published-print":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/femsle\/fnx207","relation":{},"ISSN":["1574-6968"],"issn-type":[{"value":"1574-6968","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,10]]},"published":{"date-parts":[[2017,10]]}}}