{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:07:35Z","timestamp":1792001255915,"version":"4.4.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004484","name":"Tehran University of Medical Sciences, Tehran","doi-asserted-by":"publisher","award":["31663"],"award-info":[{"award-number":["31663"]}],"id":[{"id":"10.13039\/501100004484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>This study was set to determine the genetic linkage and the clonal relationship between vancomycin-resistant Enterococcusfaecium (VREfm) isolates in three hospitals of Ahwaz city. In this study, 1050 samples were collected from various rectal swabs, hands of health care workers, environmental surfaces, medical equipment and 146 enterococci isolates from clinical sources of three hospitals from March to September 2015. Antimicrobial resistance patterns in VREfm were detected by disk diffusion method. Genetic linkages of VREfm strains were investigated by pulse field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) methods. Out of 366 enterococcal isolates, 163 Enterococcus faecium isolates were found to be resistant to vancomycin. PFGE and MLST analysis showed the presence of 79 pulsotypes and 11 sequence types (ST), respectively. In total, 90% of the isolates belonged to clonal complex 17 (CC17). Three new STs were reported for the first time in this study and ST80 was the predominant ST. We found a high prevalence of diverse VREfm with threatening antibiotic resistance patterns in all the studied sources with the dominance of CC17 VREfm strains in Ahwaz hospitals. Also, the results of typing method showed inter- and intra-hospital circulation of VREfm and similar pulsotypes and STs among different sources.<\/jats:p>","DOI":"10.1093\/femsle\/fnz062","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T20:13:29Z","timestamp":1553199209000},"source":"Crossref","is-referenced-by-count":2,"title":["Epidemiological linkage of vancomycin-resistant <i>Enterococcus faecium<\/i> from different sources in Ahwaz, Iran"],"prefix":"10.1093","volume":"366","author":[{"given":"Maniya","family":"Arshadi","sequence":"first","affiliation":[{"name":"Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leili","family":"Shokoohizadeh","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, 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