{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T21:02:11Z","timestamp":1760821331066,"version":"3.41.2"},"reference-count":137,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":152,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,18]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The transmission of infectious diseases is characterized by heterogeneities that are shaped by the host, the pathogen, and the environment. Extreme forms of these heterogeneities are called super-spreading events. Transmission heterogeneities are usually identified retrospectively, but their contribution to the dynamics of outbreaks makes the ability to predict them valuable for science, medicine, and public health. Previous studies identified several factors that facilitate super-spreading; one of them is the interaction between bacteria and viruses within a host. The heightened dispersal of bacteria colonizing the nasal cavity during an upper respiratory viral infection, and the increased shedding of HIV-1 from the urogenital tract during a sexually transmitted bacterial infection, are among the most extensively studied examples of transmission heterogeneities that result from bacterial\u2013viral interactions. Interrogating these transmission heterogeneities, and elucidating the underlying cellular and molecular mechanisms, are part of much-needed efforts to guide public health interventions, in areas that range from predicting or controlling the population transmission of respiratory pathogens, to limiting the spread of sexually transmitted infections, and tailoring vaccination initiatives with live attenuated vaccines.<\/jats:p>","DOI":"10.1093\/femsmc\/xtac018","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T14:24:35Z","timestamp":1654179875000},"source":"Crossref","is-referenced-by-count":3,"title":["Bacterial\u2013viral interactions: a factor that facilitates transmission heterogeneities"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5944-8008","authenticated-orcid":false,"given":"Richard A","family":"Stein","sequence":"first","affiliation":[{"name":"NYU Tandon School of Engineering, Department of Chemical and Biomolecular Engineering , 6 MetroTech Center , Brooklyn, NY 11201, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilia Claire","family":"Bianchini","sequence":"additional","affiliation":[{"name":"NYU Tandon School of Engineering, Department of Chemical and Biomolecular Engineering , 6 MetroTech Center , Brooklyn, NY 11201, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"2023041117224200700_","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1097\/00002030-200108170-00011","article-title":"A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding","volume":"15","author":"Al-Harthi","year":"2001","journal-title":"AIDS"},{"key":"2023041117224200700_","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/00126334-199907010-00003","article-title":"Bacterial 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