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The bacterial agents of leptospirosis infect humans through contact with soil or water contaminated by the urine of animal reservoirs. As a primarily waterborne disease, leptospirosis is strongly influenced by climatic conditions, including rainfall, flooding, and extreme events such as hurricanes and cyclones. Here, we present current knowledge on the links between climate change and leptospirosis, as well as perspectives on effective strategies to combat this disease, which disproportionately affects the poorest populations.<\/jats:p>","DOI":"10.1093\/femsml\/uqag015","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:33:23Z","timestamp":1776771203000},"source":"Crossref","is-referenced-by-count":3,"title":["Climate change and leptospirosis: a growing environmental and zoonotic threat"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1762-6336","authenticated-orcid":false,"given":"Vincent","family":"Herbreteau","sequence":"first","affiliation":[{"name":"ESPACE-DEV, IRD, Univ Montpellier, Univ. Antilles, Univ Guyane, Univ R\u00e9union , 120404 Phnom Penh ,","place":["Cambodia"]},{"name":"Khmer Earth Observation Laboratory, Institute of Technology of Cambodia, IRD , 120404 Phnom Penh ,","place":["Cambodia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5338-5579","authenticated-orcid":false,"given":"Mathieu","family":"Picardeau","sequence":"additional","affiliation":[{"name":"Institut Pasteur, French National Reference Center for Leptospirosis, WHO Collaborating Center for Reference and Research on Leptospirosis, Universit\u00e9 Paris Cit\u00e9 , Biology of Spirochetes Unit, 75015 Paris ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"2026051412154121500_bib1","doi-asserted-by":"publisher","first-page":"e18851","DOI":"10.7717\/peerj.18851","article-title":"Identifying leptospirosis hotspots in Selangor: uncovering 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