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It is associated with risk factors such as the use of indwelling medical devices, prolonged hospital stay, and broad-spectrum antibiotics use. It is especially seen in immunocompromised individuals such as patients with prolonged hospital stay, gastrointestinal surgery, haematological malignancies, and respiratory diseases. We have conducted a systematic search of literature using a select group of databases and appropriate search words and found that in Africa, there are 18\u00a0293 documented\/reported cases of invasive candidiasis in the last few decades (1976\u20132021) and 16\u00a0636(91%) were cases of candidaemia. South Africa had the highest number of reported cases\u201415\u00a0002(82%), which may be due to underreporting of cases in other countries. HIV positive persons with invasive candidiasis in Africa accounted for 1 052(5.8%). Candida albicans was the most frequently isolated species 6 328(32.6%), followed by Candida parapsilosis 5 910(30.4%), and Candida auris 1 505(7.8%). Due to the affordability and availability of blood culture, it was used for diagnosis in most of the studies examined, while a few studies combined other techniques and just three studies from two countries used serological tests. Echinocandins are recommended as first-line therapy but are only available in 12 countries and are highly priced. The use of fluconazole, because of its availability and relatively inexpensive nature, has led to increased resistance of Candida species to the drug.<\/jats:p>","DOI":"10.1093\/femspd\/ftac012","type":"journal-article","created":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T19:15:19Z","timestamp":1650482119000},"source":"Crossref","is-referenced-by-count":23,"title":["Invasive candidiasis in Africa, what is the current picture?"],"prefix":"10.1093","volume":"80","author":[{"given":"Chinonyelum A","family":"Okoye","sequence":"first","affiliation":[{"name":"Department of Microbiology, Faculty of Biological Sciences, Abia State University , Uturu, Abia State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeka","family":"Nweze","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Biological Sciences, University of Nigeria , Nsukka, Enugu State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6614-0677","authenticated-orcid":false,"given":"Chibuike","family":"Ibe","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Biological Sciences, Abia State University , Uturu, Abia State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"2022062302453062900_bib1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.21608\/ejm.2019.14099.1104","article-title":"Incidence of ICU-acquired candidemia in a tertiary care hospital in Cairo, Egypt","author":"Abass","year":"2019","journal-title":"Egypt J Microbiol"},{"key":"2022062302453062900_bib2","first-page":"4307","article-title":"Identification and in vitro susceptibility pattern of fungal pathogens in immunocomprimised patients with pulmonary fungal 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