{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T16:20:08Z","timestamp":1783786808261,"version":"3.55.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,30]]},"DOI":"10.1093\/femspd\/ftx114","type":"journal-article","created":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T11:09:19Z","timestamp":1507892959000},"source":"Crossref","is-referenced-by-count":7,"title":["Long-term cell culture isolated from lesions of mice infected with Leishmania amazonensis: a new approach to study mononuclear phagocyte subpopulations during the infection"],"prefix":"10.1093","volume":"75","author":[{"given":"Myriam Janeth Salazar","family":"Terreros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Augusto Visani","family":"de Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selma","family":"Giorgio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,10,14]]},"reference":[{"key":"key\n\t\t\t\t20171102202510_bib1","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.acthis.2012.01.007","article-title":"Infection by Leishmania amazonensis in mice: A potential model for chronic hypoxia","volume":"114","year":"2012","journal-title":"Acta Histochem"},{"key":"key\n\t\t\t\t20171102202510_bib2","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00403-015-1564-0","article-title":"Immunohistochemical evidence of stress and inflammatory markers in mouse models of cutaneous leishmaniosis","volume":"307","year":"2015","journal-title":"Arch Dermatol Res"},{"key":"key\n\t\t\t\t20171102202510_bib3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.actatropica.2006.03.001","article-title":"Hyperbaric oxygen therapy reduces the size of Leishmania amazonensis-induced soft tissue lesions in mice","volume":"98","year":"2006","journal-title":"Acta Trop"},{"key":"key\n\t\t\t\t20171102202510_bib4","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1128\/IAI.61.5.2131-2137.1993","article-title":"Glycosphingolipid antigens of Leishmania (Leishmania) amazonensis amastigotes identified by use of a monoclonal antibody","volume":"61","year":"1993","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib5","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/jac\/dkm079","article-title":"A trial of immunotherapy against Leishmania amazonensis infection in vitro and in vivo with Z-100, a polysaccharide obtained from Mycobacterium tuberculosis, alone or combined with meglumine antimoniate","volume":"59","year":"2007","journal-title":"J Antimicrob Chemoth"},{"key":"key\n\t\t\t\t20171102202510_bib6","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1128\/IAI.02909-14","article-title":"Interleukin-10 from T cells, but not macrophages and granulocytes, is required for chronic disease in Leishmania mexicana infection","volume":"83","year":"2015","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib8","doi-asserted-by":"crossref","first-page":"6270","DOI":"10.1128\/IAI.71.11.6270-6278.2003","article-title":"DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous leishmaniasis","volume":"71","year":"2003","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib9","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1089\/jir.2015.0043","article-title":"IFN-\u03b3-dependent recruitment of CD4(+) T cells and macrophages contributes to pathogenesis during Leishmania amazonensis infection","volume":"35","year":"2015","journal-title":"J Interf Cytok Res"},{"key":"key\n\t\t\t\t20171102202510_bib10","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1002\/eji.1830211036","article-title":"Phagocytosis enhances murine macrophage activation by interferon-\u03b3 and tumor necrosis factor-\u03b1","volume":"21","year":"1991","journal-title":"Eur J Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib11","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1186\/1756-3305-7-448","article-title":"Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB\/c mice against infection","volume":"7","year":"2014","journal-title":"Parasite Vector"},{"key":"key\n\t\t\t\t20171102202510_bib12","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.exppara.2011.09.015","article-title":"Lack of signaling by IL-4 or by IL-4\/IL-13 has more attenuating effects on Leishmania amazonensis dorsal skin \u2013 than on footpad-infected mice","volume":"130","year":"2012","journal-title":"Exp Parasitol"},{"key":"key\n\t\t\t\t20171102202510_bib14","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/s00011-013-0647-7","article-title":"Macrophages: plastic solutions to environmental heterogeneity","volume":"62","year":"2013","journal-title":"Inflamm Res"},{"key":"key\n\t\t\t\t20171102202510_bib15","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1128\/IAI.66.2.807-814.1998","article-title":"In vivo formation of electron paramagnetic resonance-detectable nitric oxide and of nitrotyrosine is not impaired during murine leishmaniasis","volume":"66","year":"1998","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib16","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/nri1733","article-title":"Monocyte and macrophage heterogeneity","volume":"5","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib17","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1128\/IAI.71.8.4278-4288.2003","article-title":"Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis","volume":"71","year":"2003","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib18","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/nrmicro2608","article-title":"Leishmaniasis: complexity at the host-pathogen interface","volume":"9","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"key\n\t\t\t\t20171102202510_bib19","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.micinf.2014.07.012","article-title":"Leishmania molecules that mediate intracellular pathogenesis","volume":"16","year":"2014","journal-title":"Microbes Infect"},{"key":"key\n\t\t\t\t20171102202510_bib20","first-page":"156","article-title":"Interferon gamma in Leishmaniasis","volume":"4","year":"2013","journal-title":"Front Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib21","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1128\/IAI.00912-12","article-title":"Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages","volume":"80","year":"2012","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20171102202510_bib22","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1084\/jem.165.2.546","article-title":"Cutaneous Leishmaniasis - the defect in T-cell influx in Balb\/C mice","volume":"165","year":"1987","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20171102202510_bib23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/qjmed\/hct116","article-title":"Leishmaniasis: clinical syndromes and treatment","volume":"107","year":"2014","journal-title":"QJM-Int J Med"},{"key":"key\n\t\t\t\t20171102202510_bib24","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.0105-2896.2004.00190.x","article-title":"Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?","volume":"201","year":"2004","journal-title":"Immunol Rev"},{"key":"key\n\t\t\t\t20171102202510_bib25","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1600-065X.2010.00983.x","article-title":"Cell biology and immunology of Leishmania","volume":"240","year":"2011","journal-title":"Immunol Rev"},{"key":"key\n\t\t\t\t20171102202510_bib26","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.actatropica.2015.12.016","article-title":"Visceral leishmaniasis: Revisiting current treatments and approaches for future discoveries","volume":"155","year":"2016","journal-title":"Acta Trop"},{"key":"key\n\t\t\t\t20171102202510_bib27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4103\/0974-777X.62876","article-title":"Immunological perspectives of Leishmaniasis","volume":"2","year":"2010","journal-title":"J Glob Infect Dis"},{"key":"key\n\t\t\t\t20171102202510_bib28","doi-asserted-by":"crossref","first-page":"489","DOI":"10.4269\/ajtmh.15-0408","article-title":"Social and economic burden of human Leishmaniasis","volume":"94","year":"2016","journal-title":"Am J Trop Med Hyg"},{"key":"key\n\t\t\t\t20171102202510_bib29","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.vetpar.2008.09.015","article-title":"Immunological characteristics of experimental murine infection with Leishmania (Leishmania) amazonensis","volume":"158","year":"2008","journal-title":"Vet Parasitol"},{"key":"key\n\t\t\t\t20171102202510_bib30","doi-asserted-by":"crossref","first-page":"e15018","DOI":"10.1371\/journal.pone.0015018","article-title":"Enhanced M1 macrophage polarization in human Helicobacter pylori-associated atrophic gastritis and in vaccinated mice","volume":"5","year":"2010","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20171102202510_bib31","first-page":"16","article-title":"Understanding the mysterious M2 macrophage through activation markers and effector mechanisms","volume":"2015","year":"2015","journal-title":"Mediat Inflamm"},{"key":"key\n\t\t\t\t20171102202510_bib32","doi-asserted-by":"crossref","first-page":"e1003476","DOI":"10.1371\/journal.ppat.1003476","article-title":"T cell-derived IL-10 determines Leishmaniasis disease outcome and is suppressed by a dendritic cell based vaccine","volume":"9","year":"2013","journal-title":"PLos Pathog"},{"key":"key\n\t\t\t\t20171102202510_bib33","doi-asserted-by":"crossref","first-page":"966","DOI":"10.4049\/jimmunol.131.2.966","article-title":"Resistance to macrophage-mediated killing as a factor influencing the pathogenesis of chronic cutaneous leishmaniasis","volume":"131","year":"1983","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib34","first-page":"58","article-title":"Subversion and utilization of host innate defense by Leishmania amazonensis","volume":"3","year":"2012","journal-title":"Front Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib35","doi-asserted-by":"crossref","first-page":"e0003411","DOI":"10.1371\/journal.pntd.0003411","article-title":"Regulation of Leishmania (L.) amazonensis protein expression by host T cell dependent responses: differential expression of oligopeptidase B, tryparedoxin peroxidase and HSP70 isoforms in amastigotes isolated from BALB\/c and BALB\/c nude mice","volume":"9","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t20171102202510_bib36","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1017\/S003118201600024X","article-title":"Distinct courses of infection with Leishmania (L.) amazonensis are observed in BALB\/c, BALB\/c nude and C57BL\/6 mice","volume":"143","year":"2016","journal-title":"Parasitology"},{"key":"key\n\t\t\t\t20171102202510_bib37","first-page":"6. 1","article-title":"Characterization of murine macrophages from bone marrow, spleen and peritoneum","volume":"14","year":"2013","journal-title":"BMC Immunol"},{"key":"key\n\t\t\t\t20171102202510_bib38","doi-asserted-by":"crossref","first-page":"e01670-15","DOI":"10.1128\/mBio.01670-15","article-title":"Immune homeostatic macrophages programmed by the bacterial surface protein NhhA potentiate nasopharyngeal carriage of Neisseria meningitidis","volume":"7","year":"2016","journal-title":"MBio"}],"container-title":["Pathogens and Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femspd\/article-pdf\/75\/8\/ftx114\/21515916\/ftx114.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T03:52:50Z","timestamp":1693108370000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/femspd\/article\/doi\/10.1093\/femspd\/ftx114\/4554384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,14]]},"references-count":36,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,10,14]]},"published-print":{"date-parts":[[2017,11,30]]}},"URL":"https:\/\/doi.org\/10.1093\/femspd\/ftx114","relation":{},"ISSN":["2049-632X"],"issn-type":[{"value":"2049-632X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,11]]},"published":{"date-parts":[[2017,10,14]]}}}