{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:58:51Z","timestamp":1790002731205,"version":"4.0.1"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4,1]]},"DOI":"10.1093\/femspd\/fty024","type":"journal-article","created":{"date-parts":[[2018,3,16]],"date-time":"2018-03-16T11:02:57Z","timestamp":1521198177000},"source":"Crossref","is-referenced-by-count":3,"title":["Growth characteristics of Chlamydia trachomatis in human intestinal epithelial Caco-2 cells"],"prefix":"10.1093","volume":"76","author":[{"given":"Ildik\u00f3","family":"Lantos","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Immunobiology, University of Szeged, H-6720, Szeged, D\u00f3m Sq. 10, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dezs\u0151 P","family":"Virok","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunobiology, University of Szeged, H-6720, Szeged, D\u00f3m Sq. 10, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00edmea","family":"Mosolyg\u00f3","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunobiology, University of Szeged, H-6720, Szeged, D\u00f3m Sq. 10, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"R\u00e1zga","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Szeged, H-6720, \u00c1llom\u00e1s Str. 2, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Buri\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunobiology, University of Szeged, H-6720, Szeged, D\u00f3m Sq. 10, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria","family":"Endr\u00e9sz","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunobiology, University of Szeged, H-6720, Szeged, D\u00f3m Sq. 10, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,3,16]]},"reference":[{"key":"key\n\t\t\t\t20180409073347_bib1","first-page":"a010256","article-title":"Chlamydial intracellular survival strategies","volume":"3","author":"Bastidas","year":"2013","journal-title":"CSH Perspect Med"},{"key":"key\n\t\t\t\t20180409073347_bib2","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/infdis\/jix419","article-title":"Does active oral sex contribute to female infertility?","volume":"216","author":"Bavoil","year":"2017","journal-title":"J Infect Dis 8"},{"key":"key\n\t\t\t\t20180409073347_bib3","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1136\/sti.2010.048173","article-title":"Analyses of multiple-site and concurrent Chlamydia trachomatis serovar infections, and serovar tissue tropism for urogenital versus rectal specimens in male and female patients","volume":"87","author":"Bax","year":"2011","journal-title":"Sex Transm Infect"},{"key":"key\n\t\t\t\t20180409073347_bib4","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.mimet.2010.06.013","article-title":"Normalization strategies for real-time expression data in Chlamydia trachomatis","volume":"82","author":"Borges","year":"2010","journal-title":"J Microbiol Methods"},{"key":"key\n\t\t\t\t20180409073347_bib5","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0165-2478(03)00154-8","article-title":"Chlamydophila (Chlamydia) pneumoniae induces histidine decarboxylase production in the mouse lung","volume":"89","author":"Buri\u00e1n","year":"2003","journal-title":"Immunol Lett"},{"key":"key\n\t\t\t\t20180409073347_bib6","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1186\/s12866-014-0209-3","article-title":"Differential infection outcome of Chlamydia trachomatis in human blood monocytes and monocyte-derived dendritic cells","volume":"14","author":"Datta","year":"2014","journal-title":"BMC Microbiol"},{"key":"key\n\t\t\t\t20180409073347_bib7","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1471-230X-10-19","article-title":"Chlamydia trachomatis antigens in enteroendocrine cells and macrophages of the small bowel in patients with severe irritable bowel syndrome","volume":"10","author":"Dlugosz","year":"2010","journal-title":"BMC Gastroenterol"},{"key":"key\n\t\t\t\t20180409073347_bib8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3390\/pathogens2010177","article-title":"Antimicrobial human \u03b2-defensins in the colon and their role in infectious and non-infectious diseases","volume":"2","author":"Cobo","year":"2013","journal-title":"Pathogens"},{"key":"key\n\t\t\t\t20180409073347_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.mimet.2015.11.010","article-title":"High dynamic range detection of Chlamydia trachomatis growth by direct quantitative PCR of the infected cells","volume":"120","author":"Eszik","year":"2016","journal-title":"J Microbiol Methods"},{"key":"key\n\t\t\t\t20180409073347_bib10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s004300050082","article-title":"Viability and gene expression in Chlamydia trachomatis during persistent infection of cultured human monocytes","volume":"187","author":"G\u00e9rard","year":"1998","journal-title":"Med Microbiol Immunol (Berl)"},{"key":"key\n\t\t\t\t20180409073347_bib11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.micpath.2003.08.005","article-title":"Differential expression of three Chlamydia trachomatis hsp60-encoding genes in active vs. persistent infections","volume":"36","author":"G\u00e9rard","year":"2004","journal-title":"Microb Pathogenesis"},{"key":"key\n\t\t\t\t20180409073347_bib12","doi-asserted-by":"crossref","first-page":"E40","DOI":"10.3390\/ph9030040","article-title":"Functions of cationic host defense peptides in immunity","volume":"9","author":"Hemshekhar","year":"2016","journal-title":"Pharmaceuticals"},{"key":"key\n\t\t\t\t20180409073347_bib13","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1128\/IAI.69.3.1832-1840.2001","article-title":"Inflammation and clearance of Chlamydia trachomatis in enteric and nonenteric mucosae","volume":"69","author":"Igietseme","year":"2001","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20180409073347_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.5217\/ir.2014.12.1.20","article-title":"Antimicrobial proteins in intestine and inflammatory bowel diseases","volume":"12","author":"Kim","year":"2014","journal-title":"Intest Res"},{"key":"key\n\t\t\t\t20180409073347_bib15","first-page":"44","article-title":"Commonly prescribed \u00ce\u00b2-lactam antibiotics induce C. trachomatis persistence\/stress in culture at physiologically relevant concentrations","volume":"4","author":"Kintner","year":"2014","journal-title":"Front Cell Infect Mi"},{"key":"key\n\t\t\t\t20180409073347_bib16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.micpath.2010.06.002","article-title":"Analysis of modulated gene expression in a model of Interferon-gamma-induced persistence of Chlamydia trachomatis in HEp-2 cells","volume":"49","author":"Kokab","year":"2010","journal-title":"Microb Pathogenesis"},{"key":"key\n\t\t\t\t20180409073347_bib17","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1186\/1471-2334-14-274","article-title":"High co-occurrence of anorectal chlamydia with urogenital chlamydia in women visiting an STI clinic revealed by routine universal testing in an observational study; a recommendation towards a better anorectal chlamydia control in women","volume":"14","author":"van Liere","year":"2014","journal-title":"BMC Infect Dis"},{"key":"key\n\t\t\t\t20180409073347_bib18","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1371\/journal.ppat.0030083","article-title":"Gene expression profiles of Chlamydophila pneumoniae during the developmental cycle and iron depletion mediated persistence","volume":"3","author":"M\u00e4urer","year":"2007","journal-title":"PLoS Pathog"},{"key":"key\n\t\t\t\t20180409073347_bib19","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.micres.2005.04.004","article-title":"Chlamydia trachomatis persistence: an update","volume":"161","author":"Mpiga","year":"2006","journal-title":"Microbiol Res"},{"key":"key\n\t\t\t\t20180409073347_bib20","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1128\/JB.185.10.3179-3189.2003","article-title":"Global stage-specific gene regulation during the developmental cycle of Chlamydia trachomatis","volume":"185","author":"Nicholson","year":"2003","journal-title":"J Bacteriol"},{"key":"key\n\t\t\t\t20180409073347_bib21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.0019-2805.2004.01816.x","article-title":"Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils","volume":"111","author":"Niyonsaba","year":"2004","journal-title":"Immunology"},{"key":"key\n\t\t\t\t20180409073347_bib22","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/LGT.0000000000000315","article-title":"Cervicovaginal levels of human \u03b2-Defensin 1, 2, 3, and 4 of Reproductive-Aged Women With Chlamydia trachomatis Infection","volume":"21","author":"Noda-Nicolau","year":"2017","journal-title":"J Low Genit Tract Di"},{"key":"key\n\t\t\t\t20180409073347_bib23","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1128\/AAC.02097-13","article-title":"Induction of the Chlamydia muridarum stress\/persistence response increases azithromycin treatment failure in a murine model of infection","volume":"58","author":"Phillips-Campbell","year":"2014","journal-title":"Antimicrob Agents Ch"},{"key":"key\n\t\t\t\t20180409073347_bib24","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1128\/IAI.01244-13","article-title":"Hidden in plain sight: chlamydial gastrointestinal infection and its relevance to persistence in human genital infection","volume":"82","author":"Rank","year":"2014","journal-title":"Infect Immun"},{"key":"key\n\t\t\t\t20180409073347_bib25","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3389\/fimmu.2014.00534","article-title":"The role of the immune response in Chlamydia trachomatis infection of the male genital tract: a double-edged sword","volume":"5","author":"Redgrove","year":"2014","journal-title":"Front Immunol"},{"key":"key\n\t\t\t\t20180409073347_bib26","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1111\/mmi.12804","article-title":"The transcriptional repressor EUO regulates both subsets of Chlamydia late genes","volume":"94","author":"Rosario","year":"2014","journal-title":"Mol Microbiol"},{"key":"key\n\t\t\t\t20180409073347_bib27","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/j.1365-2958.2012.08077.x","article-title":"The early gene product EUO is a transcriptional repressor that selectively regulates promoters of Chlamydia late genes","volume":"84","author":"Rosario","year":"2012","journal-title":"Mol Microbiol"},{"key":"key\n\t\t\t\t20180409073347_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1128\/JCM.20.2.217-222.1984","article-title":"Enhancement of Chlamydia trachomatis infectious progeny by cultivation of HeLa 229 cells treated with DEAE-dextran and cycloheximide","volume":"20","author":"Sabet","year":"1984","journal-title":"J Clin Microbiol"},{"key":"key\n\t\t\t\t20180409073347_bib29","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S1090-0233(03)00039-X","article-title":"Growth characteristics of porcine chlamydial strains in different cell culture systems and comparison with ovine and avian chlamydial strains","volume":"168","author":"Schiller","year":"2004","journal-title":"Vet J"},{"key":"key\n\t\t\t\t20180409073347_bib30","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.micinf.2011.03.004","article-title":"Chlamydia persistence \u2013 a tool to dissect Chlamydia\u2013host interactions","volume":"13","author":"Schoborg","year":"2011","journal-title":"Microbes Infect"},{"key":"key\n\t\t\t\t20180409073347_bib31","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1086\/652394","article-title":"Chlamydia trachomatis persistence in vitro: an overview","volume":"201","author":"Wyrick","year":"2010","journal-title":"J Infect Dis"},{"key":"key\n\t\t\t\t20180409073347_bib32","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1126\/science.286.5439.525","article-title":"\u03b2-defensins: linking innate and adaptive immunity through dendritic and T Cell CCR6","volume":"286","author":"Yang","year":"1999","journal-title":"Science"},{"key":"key\n\t\t\t\t20180409073347_bib33","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/2049-632X.12052","article-title":"Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection","volume":"68","author":"Yeruva","year":"2013","journal-title":"Pathog Dis"}],"container-title":["Pathogens and Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femspd\/article-pdf\/76\/3\/fty024\/24576625\/fty024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T10:37:32Z","timestamp":1603967852000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femspd\/article\/doi\/10.1093\/femspd\/fty024\/4939475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,16]]},"references-count":33,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,3,16]]},"published-print":{"date-parts":[[2018,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/femspd\/fty024","relation":{},"ISSN":["2049-632X"],"issn-type":[{"value":"2049-632X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,4]]},"published":{"date-parts":[[2018,3,16]]}}}