{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:53:33Z","timestamp":1781632413143,"version":"3.54.5"},"reference-count":11,"publisher":"American Physiological Society","issue":"2","license":[{"start":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T00:00:00Z","timestamp":1706918400000},"content-version":"vor","delay-in-days":33,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R35HL150778"],"award-info":[{"award-number":["R35HL150778"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI040127"],"award-info":[{"award-number":["R01AI040127"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AI109842"],"award-info":[{"award-number":["R01AI109842"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007458","name":"Qatar Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007458","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["ARG01-0517-230201"],"award-info":[{"award-number":["ARG01-0517-230201"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["PPM06-0508-230025"],"award-info":[{"award-number":["PPM06-0508-230025"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008982","name":"Qatar National Research Fund","doi-asserted-by":"publisher","award":["NPRP13S-0206-200274"],"award-info":[{"award-number":["NPRP13S-0206-200274"]}],"id":[{"id":"10.13039\/100008982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,13]]},"DOI":"10.1093\/function\/zqae007","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:08:00Z","timestamp":1706746080000},"source":"Crossref","is-referenced-by-count":3,"title":["The Reappraisal of the Reappraisal\u2014CRAC Channels Are Activated by L-Type Ca2+ Channel Blockers, Reply to Bird et al"],"prefix":"10.1152","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6759-864X","authenticated-orcid":false,"given":"Mohamed","family":"Trebak","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine , Pittsburgh, PA 15213 , USA"},{"name":"Vascular Medicine Institute, University of Pittsburgh , Pittsburgh, PA 15213 , USA"},{"name":"UPMC Hillman Cancer Center, University of Pittsburgh , Pittsburgh, PA 15213 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Machaca","sequence":"additional","affiliation":[{"name":"Calcium Signaling Group, Research Department, Weill Cornell Medicine Qatar, Education City, Qatar Foundation, Doha, 00000 , Qatar"},{"name":"Department of Physiology and Biophysics, Weill Cornell Medicine , New York, NY 10075 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick G","family":"Hogan","sequence":"additional","affiliation":[{"name":"La Jolla Institute for Immunology , La Jolla, CA 92037 , USA"},{"name":"Moores Cancer Center, University of California San Diego , La Jolla, CA 92037 , USA"},{"name":"Program in Immunology, University of California San Diego , La Jolla, CA 92037 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","published-online":{"date-parts":[[2024,2,2]]},"reference":[{"issue":"8","key":"2024031310495681900_bib1","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1096\/fj.09-131128","article-title":"Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration","volume":"23","author":"Potier","year":"2009","journal-title":"FASEB J"},{"issue":"5","key":"2024031310495681900_bib2","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1161\/CIRCRESAHA.111.246777","article-title":"Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury","volume":"109","author":"Zhang","year":"2011","journal-title":"Circ Res"},{"issue":"5","key":"2024031310495681900_bib3","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s00424-008-0491-8","article-title":"The non-excitable smooth muscle: calcium signaling and phenotypic switching during vascular disease","volume":"456","author":"House","year":"2008","journal-title":"Pflugers Arch"},{"issue":"29","key":"2024031310495681900_bib4","doi-asserted-by":"crossref","first-page":"17369","DOI":"10.1073\/pnas.2007598117","article-title":"L-type Ca(2+) channel blockers promote vascular remodeling through activation of STIM proteins","volume":"117","author":"Johnson","year":"2020","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"2024031310495681900_bib5","doi-asserted-by":"crossref","first-page":"zqad047","DOI":"10.1093\/function\/zqad047","article-title":"A reappraisal of the effects of L-type Ca(2+) channel blockers on store-operated Ca(2+) entry and heart failure","volume":"4","author":"Bird","year":"2023","journal-title":"Function (Oxf)"},{"issue":"1","key":"2024031310495681900_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/s41388-018-0425-7","article-title":"Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP\/TAZ","volume":"38","author":"Liu","year":"2019","journal-title":"Oncogene"},{"issue":"2","key":"2024031310495681900_bib7","doi-asserted-by":"crossref","first-page":"170","DOI":"10.2174\/138620710790596745","article-title":"Plasma protein binding in drug discovery and development","volume":"13","author":"Howard","year":"2010","journal-title":"Comb Chem High Throughput Screen"},{"issue":"6","key":"2024031310495681900_bib8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2165\/00003088-199630060-00003","article-title":"Measurement and analysis of unbound drug concentrations","volume":"30","author":"Wright","year":"1996","journal-title":"Clin Pharmacokinet"},{"issue":"6","key":"2024031310495681900_bib9","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2165\/00003088-199834060-00003","article-title":"Clinical pharmacokinetics of vasodilators. Part I","volume":"34","author":"Kirsten","year":"1998","journal-title":"Clin Pharmacokinet"},{"issue":"6","key":"2024031310495681900_bib10","doi-asserted-by":"crossref","first-page":"zqad054","DOI":"10.1093\/function\/zqad054","article-title":"Overcoming confounding to characterize the effects of calcium channel blockers","volume":"4","author":"Rajagopal","year":"2023","journal-title":"Function (Oxf)"},{"issue":"6","key":"2024031310495681900_bib11","doi-asserted-by":"crossref","first-page":"zqad055","DOI":"10.1093\/function\/zqad055","article-title":"How do we clean up the scientific record?","volume":"4","author":"Verkhratsky","year":"2023","journal-title":"Function (Oxf)"}],"container-title":["Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/full\/10.1093\/function\/zqae007","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1093\/function\/zqae007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T17:07:09Z","timestamp":1781629629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/full\/10.1093\/function\/zqae007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3,13]]}},"URL":"https:\/\/doi.org\/10.1093\/function\/zqae007","relation":{},"ISSN":["2633-8823"],"issn-type":[{"value":"2633-8823","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024]]},"published":{"date-parts":[[2024]]},"article-number":"zqae007"}}