{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T01:39:56Z","timestamp":1773797996910,"version":"3.50.1"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31702334"],"award-info":[{"award-number":["31702334"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31730098"],"award-info":[{"award-number":["31730098"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U19A2040"],"award-info":[{"award-number":["U19A2040"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31430088"],"award-info":[{"award-number":["31430088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91631305"],"award-info":[{"award-number":["91631305"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Natural Science Foundation of Hunan Province Grants","award":["020JJ5355"],"award-info":[{"award-number":["020JJ5355"]}]},{"name":"Natural Science Foundation of Hunan Province Grants","award":["2022JJ10035"],"award-info":[{"award-number":["2022JJ10035"]}]},{"name":"Key Research and Development Program of Hunan Province","award":["2018NK2072"],"award-info":[{"award-number":["2018NK2072"]}]},{"name":"Key Research and Development Program of Hunan Province","award":["2017NK1031"],"award-info":[{"award-number":["2017NK1031"]}]},{"DOI":"10.13039\/501100010038","name":"Earmarked Fund for China Agriculture Research System","doi-asserted-by":"publisher","award":["CARS-45"],"award-info":[{"award-number":["CARS-45"]}],"id":[{"id":"10.13039\/501100010038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013314","name":"111 Project","doi-asserted-by":"publisher","award":["D20007"],"award-info":[{"award-number":["D20007"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"name":"High-Level Talent Agglomeration Program of Hunan, China","award":["2019RS1044"],"award-info":[{"award-number":["2019RS1044"]}]},{"name":"Cooperative Innovation Center of Engineering and New Products for Developmental Biology of Hunan Province","award":["20134486"],"award-info":[{"award-number":["20134486"]}]},{"name":"Laboratory of Lingnan Modern Agriculture Project","award":["NT2021008"],"award-info":[{"award-number":["NT2021008"]}]},{"name":"Huxiang Young Talent Project of China","award":["2021RC3093"],"award-info":[{"award-number":["2021RC3093"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The expression of nuclear and mitochondrial genes, as well as their coordinated control, regulates cell proliferation, individual development, and disease in animals. However, the potential coregulation between nuclear and mitochondrial genes is unclear in triploid fishes. The two triploids (R2C and RC2) with distinct mitochondrial genomes but similar nuclear genomes exhibit different embryonic development times and growth rates. They are an excellent model for studying how nuclear and mitochondrial genes coordinate. Here, we performed the mRNA-seq of four stages of embryonic development (blastula, gastrula, segmentation, and hatching periods) in the two triploids (R2C and RC2) and their diploid inbred parents (red crucian carp and common carp). After establishing the four patterns of mitochondrial and nuclear gene expression, 270 nuclear genes regulated by mitochondrial genes were predicted. The expression levels of APC16 and Trim33 were higher in RC2 than in R2C, suggesting their potential effects on regulating embryonic development time. In addition, 308 differentially expressed genes filtered from the list of nuclear-encoded mitochondrial genes described by Mercer et al. in 2011 were considered potential genes for which nuclear genes regulate mitochondrial function. The findings might aid in our understanding of the correlation between mitochondrial and nuclear genomes as well as their synergistic effects on embryonic development.<\/jats:p>","DOI":"10.1093\/g3journal\/jkac197","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T13:47:13Z","timestamp":1659620833000},"source":"Crossref","is-referenced-by-count":2,"title":["Correlations of expression of nuclear and mitochondrial genes in triploid fish"],"prefix":"10.1093","volume":"12","author":[{"given":"Jialin","family":"Cui","sequence":"first","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Gao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueyin","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengxue","family":"Luo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Ren","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaojun","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University , Changsha 410081, Hunan, P.R. China"},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University , Guangzhou 510642, Guangdong, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"2022090108025165900_jkac197-B1","doi-asserted-by":"crossref","first-page":"e41927","DOI":"10.7554\/eLife.41927","article-title":"Nuclear genetic regulation of the human mitochondrial transcriptome","volume":"8","author":"Ali","year":"2019","journal-title":"eLife"},{"issue":"5735","key":"2022090108025165900_jkac197-B2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/282189a0","article-title":"A different genetic code in human mitochondria","volume":"282","author":"Barrell","year":"1979","journal-title":"Nature"},{"issue":"15","key":"2022090108025165900_jkac197-B3","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"issue":"2","key":"2022090108025165900_jkac197-B4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1095-8649.2007.01690.x","article-title":"Fish mitochondrial genomics: sequence, inheritance and functional variation","volume":"72","author":"Brown","year":"2008","journal-title":"J Fish Biol"},{"key":"2022090108025165900_jkac197-B5","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev.cellbio.22.010305.104638","article-title":"Mitochondrial fusion and fission in mammals","volume":"22","author":"Chan","year":"2006","journal-title":"Annu Rev Cell Dev Biol"},{"issue":"8","key":"2022090108025165900_jkac197-B6","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s11427-009-0079-3","article-title":"Biological characteristics of an improved triploid crucian carp","volume":"52","author":"Chen","year":"2009","journal-title":"Sci China C Life 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disease","volume":"14","author":"Tao","year":"2014","journal-title":"Curr Mol Med"},{"issue":"11","key":"2022090108025165900_jkac197-B28","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1002\/dvdy.24022","article-title":"Embryonic development of goldfish (Carassius auratus): a model for the study of evolutionary change in developmental mechanisms by artificial selection","volume":"242","author":"Tsai","year":"2013","journal-title":"Dev Dyn"},{"issue":"1","key":"2022090108025165900_jkac197-B29","doi-asserted-by":"crossref","first-page":"4625","DOI":"10.1038\/s41467-019-12644-1","article-title":"The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio","volume":"10","author":"Xu","year":"2019","journal-title":"Nat Commun"},{"issue":"2","key":"2022090108025165900_jkac197-B30","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ygcen.2012.06.006","article-title":"Elevated expressions of GH\/IGF axis genes in triploid crucian carp","volume":"178","author":"Zhong","year":"2012","journal-title":"Gen Comp Endocrinol"}],"container-title":["G3 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