{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:23:26Z","timestamp":1755224606662,"version":"3.43.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T00:00:00Z","timestamp":1743206400000},"content-version":"vor","delay-in-days":87,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008233","name":"Shanghai Jiao Tong University School of Medicine","doi-asserted-by":"publisher","award":["20240806"],"award-info":[{"award-number":["20240806"]}],"id":[{"id":"10.13039\/501100008233","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Delayed upper gastrointestinal transit during small bowel capsule endoscopy (SBCE) can lead to incomplete or failed examinations but can be treated by endoscopic-assisted intervention (EAI). The aim of this study was to investigate the latest possible timing of EAI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients who underwent SBCE and received EAI between July 2007 and December 2020 were retrospectively reviewed. A novel T-value was developed that accounted for the varied battery life of different generations of PillCam when determining the latest possible timing of EAI, where T is calculated as EAI time\/[minimum battery life of the PillCam minus small bowel transit time (6\u2009h)] \u00d7 100%. Patients were divided into two groups based on the cut-off value of the receiver operating characteristic curve: early EAI (group A, T\u2009&amp;lt;\u200976.3%) and late EAI (group B, T\u2009\u2265\u200976.3%). The primary outcome was the completion rate (CR), and the secondary outcome was the detection rate. The latest possible timing of EAI (h) was calculated according to the T-value formula and further verified in our recent data set.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>This study included 108 patients. The CR was significantly higher in group A than in group B (79.2% vs 58.2%; P\u2009=\u20090.018). Late EAI was an independent predictor of incomplete SBCE (odds ratio\u2009=\u20092.900; 95% confidence interval, 1.193\u20137.053). The latest possible timing of EAI was 1.5\u2009h and 4.6\u2009h from the start of the examination for PillCam SB1 and PillCam SB2\/3, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Early EAI was associated with higher CR. The latest possible timing of EAI was 1.5\u2009h for PillCam SB1 and 4.6\u2009h for PillCam SB2\/3 from the start of the examination.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gastro\/goaf011","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T15:19:27Z","timestamp":1743434367000},"source":"Crossref","is-referenced-by-count":0,"title":["Latest possible timing for endoscopic-assisted intervention in capsule endoscopy"],"prefix":"10.1093","volume":"13","author":[{"given":"Xinlong","family":"He","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, P. R.","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufeng","family":"Shen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, P. R.","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Feng","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Kunshan Second People\u2019s Hospital , Suzhou, Jiangsu, P. R.","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhifang","family":"Gao","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai, P. R.","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanbing","family":"Xue","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Digestive Diseases, Shanghai Jiao Tong University School of Medicine , Shanghai, P. 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