{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T19:04:46Z","timestamp":1782241486704,"version":"3.54.5"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ed and Joey Story Endowed Chair"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Backgrounds<\/jats:title>\n                  <jats:p>Endoscopic stricturotomy (ESt) has been shown to be effective in treating inflammatory bowel disease (IBD)-associated anastomotic strictures. However, the outcome of ESt in benign, non-IBD conditions has not been described. The aim of this study was to evaluate the outcome of ESt in the management of IBD and non-IBD-associated strictures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data of all consecutive IBD and non-IBD patients with benign anastomotic strictures treated with ESt from 2009 to 2016 were extracted. The primary outcomes were surgery-free survival and procedure-related complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 49 IBD and 15 non-IBD patients were included in this study. The IBD group included 25 patients with Crohn\u2019s disease and 24 with ulcerative colitis and ileal pouches. Underlying diseases in the non-IBD group included colorectal cancer (n\u2009=\u20097), diverticulitis (n\u2009=\u20095), large bowel prolapse (n\u2009=\u20092), and constipation (n\u2009=\u20091). Immediate technical success was achieved in all patients in both groups. Bleeding complications occurred on five occasions (4.7% per procedure) in the IBD group, while no complication occurred in the non-IBD group (P\u2009=\u20090.20). Stricture improvement on follow-up endoscopy was found in 10 (20.4%) and 5 (33.3%) patients in the IBD and non-IBD groups, respectively (P\u2009=\u20090.32). Six (12.2%) patients in the IBD group and four (26.7%) patients in the non-IBD group eventually required stricture-related surgery (P\u2009=\u20090.23). IBD patients appeared to have a higher tendency for maintaining surgery-free after the procedure than non-IBD patients (P\u2009=\u20090.08).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Endoscopic stricturotomy was shown to have comparable outcomes, though non-IBD patients seem to have a higher need for subsequent surgery but a lower complication rate than IBD patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gastro\/goz051","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T03:17:02Z","timestamp":1569640622000},"page":"143-150","source":"Crossref","is-referenced-by-count":36,"title":["Endoscopic stricturotomy in the treatment of anastomotic strictures in inflammatory bowel disease (IBD) and non-IBD patients"],"prefix":"10.1093","volume":"8","author":[{"given":"Long-Juan","family":"Zhang","sequence":"first","affiliation":[{"name":"Laboratory of General Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, P.R. China"},{"name":"Center for Inflammatory Bowel Disease, Digestive Disease and Surgery Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Lan","sequence":"first","affiliation":[{"name":"Center for Inflammatory Bowel Disease, Digestive Disease and Surgery Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Rui","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery and Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Shen","sequence":"first","affiliation":[{"name":"Center for Inflammatory Bowel Disease, Digestive Disease and Surgery Institute, The Cleveland Clinic Foundation, Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,10,21]]},"reference":[{"key":"2020050406475058600_goz051-B1","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1097\/MIB.0000000000000145","article-title":"Comparable short- and long-term outcomes of colonoscopic balloon dilation of Crohn's Disease and benign non-Crohn's Disease strictures","volume":"20","author":"Chen","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"2020050406475058600_goz051-B2","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/BF02562119","article-title":"Colorectal anastomotic stenosis: results of a survey of the ASCRS membership","volume":"32","author":"Luchtefeld","year":"1989","journal-title":"Dis Colon Rectum"},{"key":"2020050406475058600_goz051-B3","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/BF02238246","article-title":"Handsewn vs. stapled anastomoses in colon and rectal surgery: a meta-analysis","volume":"41","author":"MacRae","year":"1998","journal-title":"Dis Colon Rectum"},{"key":"2020050406475058600_goz051-B4","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1136\/gutjnl-2012-304353","article-title":"Crohn's disease complicated by strictures: a systematic review","volume":"62","author":"Rieder","year":"2013","journal-title":"Gut"},{"key":"2020050406475058600_goz051-B5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3109\/00365521.2014.968863","article-title":"Mechanisms of initiation and progression of intestinal fibrosis in IBD","volume":"50","author":"Latella","year":"2015","journal-title":"Scand J 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