{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:18:15Z","timestamp":1790201895159,"version":"4.1.0"},"reference-count":76,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1093\/gbe\/evu166","type":"journal-article","created":{"date-parts":[[2014,7,30]],"date-time":"2014-07-30T23:12:51Z","timestamp":1406761971000},"page":"2088-2095","source":"Crossref","is-referenced-by-count":157,"title":["Restriction and Recruitment\u2014Gene Duplication and the Origin and Evolution of Snake Venom Toxins"],"prefix":"10.1093","volume":"6","author":[{"given":"Adam D.","family":"Hargreaves","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin T.","family":"Swain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Hegarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren W.","family":"Logan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Mulley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,7,30]]},"reference":[{"key":"key\n\t\t\t\t20170627114204_evu166-B1","article-title":"FastQC: a quality control tool for high throughput sequence data","author":"Andrews","year":"2010"},{"key":"key\n\t\t\t\t20170627114204_evu166-B2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1186\/1471-2105-10-421","article-title":"BLAST+: architecture and applications","volume":"10","author":"Camacho","year":"2009","journal-title":"BMC Bioinformatics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B3","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1038\/ncomms2065","article-title":"Dynamic evolution of venom proteins in squamate reptiles","volume":"3","author":"Casewell","year":"2012","journal-title":"Nat Commun."},{"key":"key\n\t\t\t\t20170627114204_evu166-B4","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tree.2012.10.020","article-title":"Complex cocktails: the evolutionary novelty of venoms","volume":"28","author":"Casewell","year":"2013","journal-title":"Trends Ecol Evol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B5","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/1756-0500-4-310","article-title":"A multi-organ transcriptome resource for the Burmese python (Python molurus bivittatus)","volume":"4","author":"Castoe","year":"2011","journal-title":"BMC Res Notes."},{"key":"key\n\t\t\t\t20170627114204_evu166-B6","doi-asserted-by":"crossref","first-page":"20645","DOI":"10.1073\/pnas.1314475110","article-title":"The Burmese python genome reveals the molecular basis for extreme adaptation in snakes","volume":"110","author":"Castoe","year":"2013","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B7","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1098\/rspb.2004.2969","article-title":"Rates and patterns of gene duplication and loss in the human genome","volume":"272","author":"Cotton","year":"2005","journal-title":"Proc Biol Sci."},{"key":"key\n\t\t\t\t20170627114204_evu166-B8","doi-asserted-by":"crossref","first-page":"21593","DOI":"10.1073\/pnas.1007883107","article-title":"Evolution of an antifreeze protein by neofunctionalization under escape from adaptive conflict","volume":"107","author":"Deng","year":"2010","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B9","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1101\/gr.087932.108","article-title":"Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard","volume":"19","author":"Di-Poi","year":"2009","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20170627114204_evu166-B10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/1471-2164-12-259","article-title":"Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing","volume":"12","author":"Durban","year":"2011","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B11","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1371\/journal.pgen.0020102","article-title":"Neofunctionalization in vertebrates: the example of retinoic acid receptors","volume":"2","author":"Escriva","year":"2006","journal-title":"PLOS Genet."},{"key":"key\n\t\t\t\t20170627114204_evu166-B12","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1016\/j.jprot.2012.02.021","article-title":"Venomics and antivenomics profiles of North African Cerastes cerastes and C. vipera populations reveals a potentially important therapeutic weakness","volume":"75","author":"Fahmi","year":"2012","journal-title":"J Proteomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B13","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1093\/genetics\/151.4.1531","article-title":"Preservation of duplicate genes by complementary, degenerative mutations","volume":"151","author":"Force","year":"1999","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B14","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/pmic.200700777","article-title":"Exploring snake venom proteomes: multifaceted analyses for complex toxin mixtures","volume":"8","author":"Fox","year":"2008","journal-title":"Proteomics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B15","doi-asserted-by":"crossref","first-page":"12775","DOI":"10.1073\/pnas.91.26.12775","article-title":"Molecular cloning and derived primary structure of cobra venom factor","volume":"91","author":"Fritzinger","year":"1994","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B16","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.4049\/jimmunol.149.11.3554","article-title":"Primary structure of cobra complement component C3","volume":"149","author":"Fritzinger","year":"1992","journal-title":"J Immunol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B17","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1101\/gr.3228405","article-title":"From genome to \u201cvenome\u201d: molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins","volume":"15","author":"Fry","year":"2005","journal-title":"Genome Res."},{"key":"key\n\t\t\t\t20170627114204_evu166-B18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.toxicon.2012.02.013","article-title":"The structural and functional diversification of the Toxicofera reptile venom system","volume":"60","author":"Fry","year":"2012","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B19","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nature04328","article-title":"Early evolution of the venom system in lizards and snakes","volume":"439","author":"Fry","year":"2006","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170627114204_evu166-B20","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1074\/mcp.M700094-MCP200","article-title":"Evolution of an arsenal: structural and functional diversification of the venom system in the advanced snakes (Caenophidia)","volume":"7","author":"Fry","year":"2008","journal-title":"Mol Cell Proteomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B21","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1074\/mcp.M112.023143","article-title":"Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in Toxicoferan reptiles","volume":"12","author":"Fry","year":"2013","journal-title":"Mol Cell Proteomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B22","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1146\/annurev.genom.9.081307.164356","article-title":"The Toxicogenomic multiverse: convergent recruitment of proteins into animal venoms","volume":"10","author":"Fry","year":"2009","journal-title":"Annu Rev Genomics Hum Genet."},{"key":"key\n\t\t\t\t20170627114204_evu166-B23","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.toxicon.2012.03.005","article-title":"Novel transcripts in the maxillary venom glands of advanced snakes","volume":"59","author":"Fry","year":"2012","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B24","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jprot.2009.01.009","article-title":"Evolution and diversification of the Toxicofera reptile venom system","volume":"72","author":"Fry","year":"2009","journal-title":"J Proteomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B25","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1093\/molbev\/msh091","article-title":"Assembling an arsenal: origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences","volume":"21","author":"Fry","year":"2004","journal-title":"Mol Biol Evol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B26","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/nbt.1883","article-title":"Full-length transcriptome assembly from RNA-seq data without a reference genome","volume":"29","author":"Grabherr","year":"2011","journal-title":"Nat Biotechnol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B27","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1096\/fasebj.27.1_supplement.550.6","article-title":"Transcriptional regulation of trocarin D, a prothrombin activator from Tropidechis carinatus","volume":"27","author":"Han","year":"2013","journal-title":"FASEB J."},{"key":"key\n\t\t\t\t20170627114204_evu166-B28","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.toxicon.2005.02.017","article-title":"The bradykinin-potentiating peptides from venom gland and brain of Bothrops jararaca contain highly site specific inhibitors of the somatic angiotensin-converting enzyme","volume":"45","author":"Hayashi","year":"2005","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B29","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1046\/j.1471-4159.2003.01743.x","article-title":"The C-type natriuretic peptide precursor of snake brain contains highly specific inhibitors of the angiotensin-converting enzyme","volume":"85","author":"Hayashi","year":"2003","journal-title":"J Neurochem."},{"key":"key\n\t\t\t\t20170627114204_evu166-B30","doi-asserted-by":"crossref","first-page":"e206","DOI":"10.1371\/journal.pbio.0020206","article-title":"Gene duplication: the genomic trade in spare parts","volume":"2","author":"Hurles","year":"2004","journal-title":"PLOS Biol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.gene.2010.04.001","article-title":"Unique structural characteristics and evolution of a cluster of venom phospholipase A2 isozyme genes of Protobothrops flavoviridis snake","volume":"461","author":"Ikeda","year":"2010","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170627114204_evu166-B32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2164-12-1","article-title":"Venom gland transcriptomes of two elapid snakes (Bungarus multicinctus and Naja atra) and evolution of toxin genes","volume":"12","author":"Jiang","year":"2011","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B33","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1046\/j.1440-1681.2002.03725.x","article-title":"Molecular moulds with multiple missions: functional sites in three-finger toxins","volume":"29","author":"Kini","year":"2002","journal-title":"Clin Exp Pharmacol Physiol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B34","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.toxicon.2003.11.002","article-title":"Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes","volume":"42","author":"Kini","year":"2003","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B35","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.toxicon.2010.07.010","article-title":"Structure, function and evolution of three-finger toxins: mini proteins with multiple targets","volume":"56","author":"Kini","year":"2010","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B36","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1042\/BJ20040569","article-title":"Sputa nerve growth factor forms a preferable substitute to mouse 7S-beta nerve growth factor","volume":"383","author":"Koh","year":"2004","journal-title":"Biochem J."},{"key":"key\n\t\t\t\t20170627114204_evu166-B37","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0378-1119(00)00490-X","article-title":"Adaptive evolution of animal toxin multigene families","volume":"261","author":"Kordi\u0161","year":"2000","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170627114204_evu166-B38","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.toxicon.2007.01.019","article-title":"Proteome and immunome of the venom of the Thai cobra, Naja kaouthia","volume":"49","author":"Kulkeaw","year":"2007","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B39","doi-asserted-by":"crossref","first-page":"257","DOI":"10.5772\/23426","article-title":"Duplication of coagulation factor genes and evolution of snake venom prothrombin activators","volume-title":"Gene duplication","author":"Kwong","year":"2011"},{"issue":"3","key":"key\n\t\t\t\t20170627114204_evu166-B40","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1160\/TH09-03-0162","article-title":"The recruitment of blood coagulation factor X into snake venom gland as a toxin: the role of promoter cis-elements in its expression","volume":"102","author":"Kwong","year":"2009","journal-title":"Thromb Haemost."},{"key":"key\n\t\t\t\t20170627114204_evu166-B41","volume-title":"The methodology of scientific research programmes: Volume 1: Philosophical papers","author":"Lakatos","year":"1980"},{"key":"key\n\t\t\t\t20170627114204_evu166-B42","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1160\/TH04-11-0707","article-title":"Gene duplication of coagulation factor V and origin of venom prothrombin activator in Pseudonaja textilis snake","volume":"93","author":"Le","year":"2005","journal-title":"Thromb Haemost."},{"key":"key\n\t\t\t\t20170627114204_evu166-B43","first-page":"349","article-title":"Isolation of nerve growth factor (NGF) from human body fluids; saliva, serum and urine: comparison between cobra venom and cobra serum NGF","volume":"9","author":"Lipps","year":"2000","journal-title":"J Nat Toxins."},{"key":"key\n\t\t\t\t20170627114204_evu166-B44","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1126\/science.290.5494.1151","article-title":"The evolutionary fate and consequences of duplicate genes","volume":"290","author":"Lynch","year":"2000","journal-title":"Science"},{"key":"key\n\t\t\t\t20170627114204_evu166-B45","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1023\/A:1022696612931","article-title":"The evolutionary demography of duplicate genes","volume":"3","author":"Lynch","year":"2003","journal-title":"J Struct Funct Genomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B46","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1093\/genetics\/154.1.459","article-title":"The probability of duplicate gene preservation by subfunctionalization","volume":"154","author":"Lynch","year":"2000","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B47","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2148-7-2","article-title":"Inventing an arsenal: adaptive evolution and neofunctionalization of snake venom phospholipase A2 genes","volume":"7","author":"Lynch","year":"2007","journal-title":"BMC Evol Biol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B48","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1095-8312.2004.00332.x","article-title":"\u201cWhy polyploidy is rarer in animals than in plants\u201d: myths and mechanisms","volume":"82","author":"Mable","year":"2004","journal-title":"Biol J Linn Soc."},{"key":"key\n\t\t\t\t20170627114204_evu166-B49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2164-14-531","article-title":"The venom-gland transcriptome of the Eastern coral snake (Micrurus fulvius) reveals high venom complexity in the intragenomic evolution of venoms","volume":"14","author":"Margres","year":"2013","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B50","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0014-5793(00)01199-6","article-title":"Vertebrate pseudogenes","volume":"468","author":"Mighell","year":"2000","journal-title":"FEBS Lett."},{"key":"key\n\t\t\t\t20170627114204_evu166-B51","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1073\/pnas.94.4.1189","article-title":"Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide","volume":"94","author":"Murayama","year":"1997","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B52","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-86659-3","volume-title":"Evolution by gene duplication","author":"Ohno","year":"1970"},{"key":"key\n\t\t\t\t20170627114204_evu166-B53","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1146\/annurev.genet.34.1.401","article-title":"Polyploid incidence and evolution","volume":"34","author":"Otto","year":"2000","journal-title":"Annu Rev Genet."},{"key":"key\n\t\t\t\t20170627114204_evu166-B54","volume-title":"The logic of scientific discovery","author":"Popper","year":"1959"},{"key":"key\n\t\t\t\t20170627114204_evu166-B55","doi-asserted-by":"crossref","first-page":"R52","DOI":"10.1016\/j.cub.2004.12.053","article-title":"Evolutionary genomics: new genes for new jobs","volume":"15","author":"Presgraves","year":"2005","journal-title":"Curr Biol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B56","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.toxicon.2003.10.019","article-title":"Structure and chromosomal localization of the gene for crotamine, a toxin from the South American rattlesnake, Crotalus durissus terrificus","volume":"42","author":"R\u00e1dis-Baptista","year":"2003","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B57","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.toxicon.2004.02.023","article-title":"Identification of crotasin, a crotamine-related gene of Crotalus durissus terrificus","volume":"43","author":"R\u00e1dis-Baptista","year":"2004","journal-title":"Toxicon"},{"key":"key\n\t\t\t\t20170627114204_evu166-B58","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1538-7836.2006.02266.x","article-title":"Structure of two genes encoding parallel prothrombin activators in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland","volume":"5","author":"Reza","year":"2007","journal-title":"J Thromb Haemost."},{"key":"key\n\t\t\t\t20170627114204_evu166-B59","volume-title":"Just so stories","author":"Kipling","year":"1902"},{"key":"key\n\t\t\t\t20170627114204_evu166-B60","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/j.1365-294X.2012.05750.x","article-title":"Dissecting molecular stress networks: identifying nodes of divergence between life-history phenotypes","volume":"22","author":"Schwartz","year":"2013","journal-title":"Mol Ecol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B61","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1186\/1471-2164-11-694","article-title":"A garter snake transcriptome: pyrosequencing, de novo assembly, and sex-specific differences","volume":"11","author":"Schwartz","year":"2010","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B62","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1073\/pnas.0606204104","article-title":"Phylogenomics of nonavian reptiles and the structure of the ancestral amniote genome","volume":"104","author":"Shedlock","year":"2007","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B63","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1534\/genetics.112.143370","article-title":"Why transcription factor binding sites are ten nucleotides long","volume":"192","author":"Stewart","year":"2012","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170627114204_evu166-B64","doi-asserted-by":"crossref","first-page":"e81827","DOI":"10.1371\/journal.pone.0081827","article-title":"Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenal","volume":"8","author":"Sunagar","year":"2013","journal-title":"PLOS One"},{"key":"key\n\t\t\t\t20170627114204_evu166-B65","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1093\/molbev\/mss058","article-title":"Evolution of CRISPs associated with Toxicoferan-reptilian venom and mammalian reproduction","volume":"29","author":"Sunagar","year":"2012","journal-title":"Mol Biol Evol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2041-9139-2-19","article-title":"Reptilian-transcriptome v1. 0, a glimpse in the brain transcriptome of five divergent Sauropsida lineages and the phylogenetic position of turtles","volume":"2","author":"Tzika","year":"2011","journal-title":"EvoDevo."},{"key":"key\n\t\t\t\t20170627114204_evu166-B67","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1104\/pp.106.087981","article-title":"A novel family of lectins evolutionarily related to class V chitinases: an example of neofunctionalization in legumes","volume":"144","author":"Van Damme","year":"2007","journal-title":"Plant Physiol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B68","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.crvi.2005.10.001","article-title":"The phylogeny of squamate reptiles (lizards, snakes, and amphisbaenians) inferred from nine nuclear protein-coding genes","volume":"328","author":"Vidal","year":"2005","journal-title":"C R Biol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B69","doi-asserted-by":"crossref","first-page":"20651","DOI":"10.1073\/pnas.1314702110","article-title":"The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system","volume":"110","author":"Vonk","year":"2013","journal-title":"Proc Natl Acad Sci U S A."},{"key":"key\n\t\t\t\t20170627114204_evu166-B70","doi-asserted-by":"crossref","first-page":"e184","DOI":"10.1371\/journal.pmed.0030184","article-title":"Bioinformatics and multiepitope DNA immunization to design rational snake antivenom","volume":"3","author":"Wagstaff","year":"2006","journal-title":"PLOS Med"},{"key":"key\n\t\t\t\t20170627114204_evu166-B71","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jprot.2008.10.003","article-title":"Combined snake venomics and venom gland transcriptomic analysis of the ocellated carpet viper, Echis ocellatus","volume":"71","author":"Wagstaff","year":"2009","journal-title":"J Proteomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B72","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1152\/physiolgenomics.00162.2010","article-title":"Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation","volume":"43","author":"Wall","year":"2011","journal-title":"Physiol Genomics."},{"key":"key\n\t\t\t\t20170627114204_evu166-B73","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0140-6736(09)61754-2","article-title":"Snake bite","volume":"375","author":"Warrell","year":"2010","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170627114204_evu166-B74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2012.01.009","article-title":"Venom evolution through gene duplications","volume":"496","author":"Wong","year":"2012","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170627114204_evu166-B75","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/molbev\/msg140","article-title":"The evolution of transcriptional regulation in eukaryotes","volume":"20","author":"Wray","year":"2003","journal-title":"Mol Biol Evol."},{"key":"key\n\t\t\t\t20170627114204_evu166-B76","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0169-5347(03)00033-8","article-title":"Evolution by gene duplication: an update","volume":"18","author":"Zhang","year":"2003","journal-title":"Trends Ecol Evol."}],"container-title":["Genome Biology and Evolution"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/gbe\/article-pdf\/6\/8\/2088\/17924029\/evu166.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T13:02:25Z","timestamp":1689426145000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/gbe\/article-lookup\/doi\/10.1093\/gbe\/evu166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,30]]},"references-count":76,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2014,7,30]]},"published-print":{"date-parts":[[2014,8]]}},"URL":"https:\/\/doi.org\/10.1093\/gbe\/evu166","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/006023","asserted-by":"object"}]},"ISSN":["1759-6653"],"issn-type":[{"value":"1759-6653","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,30]]}}}