{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T18:29:21Z","timestamp":1760898561667},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[1998,8,1]],"date-time":"1998-08-01T00:00:00Z","timestamp":901929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1998,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Conidiation in Aspergillus nidulans is induced by exposure to red light but can also be induced by blue light in certain mutant strains. We have isolated a mutation in the fluG gene that abolishes responsiveness to red light but does not affect the response to blue light. It has been shown that the veA1 (velvet) mutation allows conidiation to occur in the absence of light. We have identified three other fluG mutations that suppress the veA1 phenotype; these double mutants do not conidiate in the dark. The mutations described here define two new phenotypic classes of fluG alleles that display abnormal responses to light. We have characterized these mutations with respect to their molecular identity and to their effect on fluG transcription. Although it has been shown that fluG is required for the synthesis of an extracellular factor that directs conidiation, we do not detect this factor under conditions that promote conidiation in the veA1 suppressors. Furthermore, extracellular rescue is not observed in fluG deletion strains containing the wild-type veA allele. We propose that a genetic interaction between fluG and veA influences the production of the extracellular signal and regulates the initiation of conidiation.<\/jats:p>","DOI":"10.1093\/genetics\/149.4.1777","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T01:55:06Z","timestamp":1619574906000},"page":"1777-1786","source":"Crossref","is-referenced-by-count":40,"title":["Analysis of fluG Mutations That Affect Light-Dependent Conidiation in Aspergillus nidulans"],"prefix":"10.1093","volume":"149","author":[{"given":"Lawrence N","family":"Yager","sequence":"first","affiliation":[{"name":"Department of Biology, Temple University, Philadelphia, Pennsylvania 19122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung-Ok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah L","family":"Nagle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E","family":"Zimmerman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1998,8,1]]},"reference":[{"key":"2022010310402972200_R1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0092-8674(88)90198-5","article-title":"brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans","volume":"54","author":"Adams","year":"1988","journal-title":"Cell"},{"key":"2022010310402972200_R2","first-page":"3827","article-title":"Isolation of a gene required for programmed initiation of development by Aspergillus nidulans","volume":"12","author":"Adams","year":"1992","journal-title":"Mol. 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