{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:47:10Z","timestamp":1773665230962,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The B chromosome of maize has been used in a study of dicentric chromosomes. TB-9Sb is a translocation between the B and chromosome 9. The B-9 of TB-9Sb carries 60% of the short arm of 9. For construction of dicentrics, a modified B-9 chromosome was used, B-9-Dp9. It consists of the B-9 chromosome plus a duplicated 9S region attached to the distal end. In meiosis, fold-back pairing and crossing over in the duplicated region gives a chromatid-type dicentric B-9 that subsequently initiates a chromatid-type breakage-fusion-bridge cycle. In the male, it forms a single bridge in anaphase II of meiosis and at the first pollen mitosis. However, the cycle is interrupted by nondisjunction of the B centromere at the second pollen mitosis, which sends the B-9 dicentric to one pole and converts it from a chromatid dicentric to a chromosome dicentric. As expected, the new dicentric undergoes the chromosome-type breakage-fusion-bridge cycle and produces double bridges. A large number of plants with chromosome dicentrics were produced in this way. The presence of double bridges in the root cells of plants with a chromosome dicentric was studied during the first 10 wk of development. It was found that the number of plants and cells showing double bridges declined steadily over the 10-wk period. Several lines of evidence indicate that there was no specific developmental time for dicentric loss. \u201cHealing\u201d of broken chromosomes produced by dicentric breakage accounted for much of the dicentric loss. Healing produced a wide range of derived B-9 chromosomes, some large and some small. A group of minichromosomes found in these experiments probably represents the small end of the scale for B-9 derivatives.<\/jats:p>","DOI":"10.1093\/genetics\/153.3.1435","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T05:11:38Z","timestamp":1619586698000},"page":"1435-1444","source":"Crossref","is-referenced-by-count":52,"title":["Time Course Study of the Chromosome-Type Breakage-Fusion-Bridge Cycle in Maize"],"prefix":"10.1093","volume":"153","author":[{"given":"Yin-Zhou","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin R","family":"Roseman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne R","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1999,11,1]]},"reference":[{"key":"2022010403532254300_R1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/BF00332608","article-title":"Observations on dicentrics in living cells","volume":"14","author":"Bajer","year":"1963","journal-title":"Chromosoma (Berl.)"},{"key":"2022010403532254300_R2","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/BF00352297","article-title":"An unstable minichromosome generates variegated oil yellow maize seedlings","volume":"104","author":"Brock","year":"1996","journal-title":"Chromosoma"},{"key":"2022010403532254300_R3","first-page":"107","article-title":"Details of the smear technique for studying chromosomes in maize","volume-title":"Maize for Biological Research","author":"Burnham","year":"1982"},{"key":"2022010403532254300_R4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1146\/annurev.ge.12.120178.000253","article-title":"The B-chromosome of corn","volume":"12","author":"Carlson","year":"1978","journal-title":"Annu. Rev. Genet."},{"key":"2022010403532254300_R5","first-page":"259","article-title":"The cytogenetics of corn","volume-title":"Corn and Corn Improvement","author":"Carlson","year":"1988"},{"key":"2022010403532254300_R6","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1093\/genetics\/143.4.1785","article-title":"Physical and genetic mapping of chromosome 9S in maize using mutations with terminal deficiencies","volume":"143","author":"Chao","year":"1996","journal-title":"Genetics"},{"key":"2022010403532254300_R7","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/978-1-4612-2694-9_74","article-title":"A technique for the preparation of somatic chromosomes of maize","volume-title":"The Maize Handbook","author":"Kindiger","year":"1994"},{"key":"2022010403532254300_R8","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1139\/g87-126","article-title":"Meiotic behavior of a tiny fragment chromosome that carries a transposed centromere","volume":"29","author":"Maguire","year":"1987","journal-title":"Genome"},{"key":"2022010403532254300_R9","first-page":"1","article-title":"The fusion of broken ends of sister half-chromatids following chromatid breakage at meiotic anaphases","volume":"290","author":"McClintock","year":"1938","journal-title":"Mo. Agric. Exp. Stn. Res. Bull."},{"key":"2022010403532254300_R10","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1073\/pnas.25.8.405","article-title":"The behavior in successive nuclear divisions of a chromosome broken at meiosis","volume":"25","author":"McClintock","year":"1939","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022010403532254300_R11","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/genetics\/26.2.234","article-title":"The stability of broken ends of chromosomes in Zea mays","volume":"26","author":"McClintock","year":"1941","journal-title":"Genetics"},{"key":"2022010403532254300_R12","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1101\/SQB.1941.009.01.010","article-title":"Spontaneous alterations in chromosome size and form in Zea mays","volume":"9","author":"McClintock","year":"1941","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"key":"2022010403532254300_R13","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1073\/pnas.28.11.458","article-title":"The fusion of broken ends of chromosomes following nuclear fusion","volume":"28","author":"McClintock","year":"1942","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2022010403532254300_R14","first-page":"148","article-title":"Maize genetics","volume":"42","author":"McClintock","year":"1943","journal-title":"Carnegie Inst. Wash. Ybk."},{"key":"2022010403532254300_R15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1101\/SQB.1951.016.01.004","article-title":"Chromosome organization and genic expression","volume":"16","author":"McClintock","year":"1951","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"key":"2022010403532254300_R16","first-page":"25","article-title":"Mechanisms that rapidly reorganize the genome","volume":"10","author":"McClintock","year":"1978","journal-title":"Stadler Genet. Symp."},{"key":"2022010403532254300_R17","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1093\/genetics\/26.6.608","article-title":"Genetic characteristics of the B chromosomes in maize","volume":"26","author":"Randolph","year":"1941","journal-title":"Genetics"},{"key":"2022010403532254300_R18","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/genetics\/55.3.433","article-title":"Crossing over and chromosomal segregation involving the B-9 element of the A-B translocation B-9b in maize","volume":"55","author":"Robertson","year":"1967","journal-title":"Genetics"},{"key":"2022010403532254300_R19","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/BF00337384","article-title":"Analysis of centromeric activity in Robertsonian translocations: implications for a functional acrocentric hierarchy","volume":"103","author":"Sullivan","year":"1994","journal-title":"Chromosoma"},{"key":"2022010403532254300_R20","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/BF00364726","article-title":"A stable dicentric chromosome: both centromeres develop kinetochores and attach to the spindle in monocentric and dicentric configuration","volume":"103","author":"Wandall","year":"1994","journal-title":"Chromosoma"}],"container-title":["Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/genetics\/article-pdf\/153\/3\/1435\/42025268\/genetics1435.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/genetics\/article-pdf\/153\/3\/1435\/42025268\/genetics1435.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T03:54:18Z","timestamp":1641268458000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/genetics\/article\/153\/3\/1435\/6050796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11,1]]},"references-count":20,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1999,11,1]]},"published-print":{"date-parts":[[1999,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/genetics\/153.3.1435","relation":{},"ISSN":["1943-2631"],"issn-type":[{"value":"1943-2631","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1999,11,1]]},"published":{"date-parts":[[1999,11,1]]}}}