{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:00:07Z","timestamp":1753876807423,"version":"3.41.2"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"American Heart Association AIREA Award","award":["33960109"],"award-info":[{"award-number":["33960109"]}]},{"name":"National Institutes of Health SCORE","award":["SC2GM136608"],"award-info":[{"award-number":["SC2GM136608"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Muscles are required for animal movement, feeding, heartbeat, and reproduction. Disruption of muscle function can lead to mobility impairments and diseases like muscular dystrophy and cardiac myopathy; therefore, research in this area has significant implications for public health. Recent work by Vaziri and colleagues has taken genetic, cell biological, and biochemical approaches to identify Protein kinase C-d (Pkc\u03b4) as a novel regulator of the essential myosin light chain 2 (MLC2) by phosphorylation. The authors determine which residues of MLC2 are modified by Pkc\u03b4 and show that phosphorylation by Pkc\u03b4 is required for proper sarcomere assembly and function. This study underscores the importance of Drosophila melanogaster as a model system for muscle function and highlights how protein phosphorylation is a vital part of post-translational gene regulation.<\/jats:p>","DOI":"10.1093\/genetics\/iyab187","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T16:43:49Z","timestamp":1646325829000},"source":"Crossref","is-referenced-by-count":0,"title":["Taking flight: an educational primer for use with \u201cA novel mechanism for activation of myosin regulatory light chain by protein kinase C-delta in <i>Drosophila<\/i>\u201d"],"prefix":"10.1093","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8548-8356","authenticated-orcid":false,"given":"Scott J","family":"Nowak","sequence":"first","affiliation":[{"name":"Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, GA 30144, USA"},{"name":"Master of Science in Integrative Biology Program, Kennesaw State University, Kennesaw, GA 30144, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krista C","family":"Dobi","sequence":"additional","affiliation":[{"name":"Department of Natural Sciences, Bernard M. 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