{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:43:38Z","timestamp":1780076618460,"version":"3.54.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["BCS-2116322"],"award-info":[{"award-number":["BCS-2116322"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In a genetically admixed population, admixed individuals possess genealogical and genetic ancestry from multiple source groups. Under a mechanistic model of admixture, we study the number of distinct ancestors from the source populations that the admixture represents. Combining a mechanistic admixture model with a recombination model that describes the probability that a genealogical ancestor is a genetic ancestor, for a member of a genetically admixed population, we count genetic ancestors from the source populations\u2014those genealogical ancestors from the source populations who contribute to the genome of the modern admixed individual. We compare patterns in the numbers of genealogical and genetic ancestors across the generations. To illustrate the enumeration of genetic ancestors from source populations in an admixed group, we apply the model to the African-American population, extending recent results on the numbers of African and European genealogical ancestors that contribute to the pedigree of an African-American chosen at random, so that we also evaluate the numbers of African and European genetic ancestors who contribute to random African-American genomes. The model suggests that the autosomal genome of a random African-American born in the interval 1960\u20131965 contains genetic contributions from a mean of 162 African (standard deviation 47, interquartile range 127\u2013192) and 32 European ancestors (standard deviation 14, interquartile range 21\u201343). The enumeration of genetic ancestors can potentially be performed in other diploid species in which admixture and recombination models can be specified.<\/jats:p>","DOI":"10.1093\/genetics\/iyae011","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T17:41:08Z","timestamp":1706636468000},"source":"Crossref","is-referenced-by-count":10,"title":["Counting the genetic ancestors from source populations in members of an admixed population"],"prefix":"10.1093","volume":"226","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-0369","authenticated-orcid":false,"given":"Lily","family":"Agranat-Tamir","sequence":"first","affiliation":[{"name":"Department of Biology, Stanford University , Stanford, CA 94305 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2369-0855","authenticated-orcid":false,"given":"Jazlyn A","family":"Mooney","sequence":"additional","affiliation":[{"name":"Department of Quantitative & Computational Biology, University of Southern California , Los Angeles, CA 90089 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1829-8664","authenticated-orcid":false,"given":"Noah A","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Biology, Stanford University , Stanford, CA 94305 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"2024091717070425500_iyae011-B1","author":"Armstrong","year":"2023"},{"key":"2024091717070425500_iyae011-B2","doi-asserted-by":"publisher","first-page":"e1006059","DOI":"10.1371\/journal.pgen.1006059","article-title":"The great migration and African-American genomic diversity","volume":"12","author":"Baharian","year":"2016","journal-title":"PLoS 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