{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:51:22Z","timestamp":1791409882274,"version":"4.3.3"},"reference-count":0,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:00:00Z","timestamp":1791331200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Modern biology depends on invisible infrastructure that is essential yet precariously funded. Millions of biological observations are interpreted through resources that sit beneath routine scientific practice, largely unseen in everyday research. Every experiment, genome analysis, AI model, and clinical interpretation relies on these biological knowledgebases, which most researchers rarely notice until they disappear. That infrastructure is now under threat. Across the world, the biological databases that underpin modern research, built over decades of public and charitable investment, face severe and increasing financial instability. This crisis arrives at a particularly damaging moment: many governments have identified life sciences as a strategic growth sector and are investing heavily in genomics, AI-enabled drug discovery, and precision medicine. Yet every one of these ambitions ultimately depends on curated biological data resources reliant on emergency bridge grants, donations, staff secondments, and ad hoc rescue efforts.<\/jats:p>","DOI":"10.1093\/genetics\/iyag274","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:09:00Z","timestamp":1791407340000},"source":"Crossref","is-referenced-by-count":0,"title":["Invisible Infrastructure at Risk: Funding Crises Threaten Global Bioscience Research"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6330-7526","authenticated-orcid":false,"given":"Valerie","family":"Wood","sequence":"first","affiliation":[{"name":"Department of Biochemistry, University of Cambridge , Cambridge ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8380-5247","authenticated-orcid":false,"given":"Elspeth A","family":"Bruford","sequence":"additional","affiliation":[{"name":"Department of Haematology, School of Clinical Medicine, University of Cambridge , Cambridge ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2759-266X","authenticated-orcid":false,"given":"Steven J","family":"Marygold","sequence":"additional","affiliation":[{"name":"Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie B","family":"O\u2019Donnell","sequence":"additional","affiliation":[{"name":"School of Medicine, Heath Park, Cardiff University , Cardiff ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3361-766X","authenticated-orcid":false,"given":"Katja","family":"R\u00f6per","sequence":"additional","affiliation":[{"name":"Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie A","family":"Davies","sequence":"additional","affiliation":[{"name":"Edinburgh Medical School, The University of Edinburgh , Edinburgh ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Orengo","sequence":"additional","affiliation":[{"name":"Institute of Structural and Molecular Biology, University College London , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Nurse","sequence":"additional","affiliation":[{"name":"The Francis Crick Institute , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2808-0009","authenticated-orcid":false,"given":"Neil","family":"Hall","sequence":"additional","affiliation":[{"name":"The Earlham Institute, Norwich Research Park , Norwich, NR4 7UZ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,7]]},"container-title":["GENETICS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/genetics\/advance-article-pdf\/doi\/10.1093\/genetics\/iyag274\/71668336\/iyag274.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/genetics\/advance-article-pdf\/doi\/10.1093\/genetics\/iyag274\/71668336\/iyag274.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:09:02Z","timestamp":1791407342000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/genetics\/advance-article\/doi\/10.1093\/genetics\/iyag274\/8876112"}},"subtitle":[],"editor":[{"given":"Howard","family":"Lipshitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,10,7]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1093\/genetics\/iyag274","relation":{},"ISSN":["1943-2631"],"issn-type":[{"value":"1943-2631","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,7]]},"article-number":"iyag274"}}