{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:59:04Z","timestamp":1788404344909,"version":"build-2803163510"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:00:00Z","timestamp":1585872000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AG51421"],"award-info":[{"award-number":["AG51421"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["CAWT16SARC2"],"award-info":[{"award-number":["CAWT16SARC2"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["BHAS16SARC2"],"award-info":[{"award-number":["BHAS16SARC2"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"California Pacific Medical Center Foundation","award":["U01AG05142"],"award-info":[{"award-number":["U01AG05142"]}]},{"name":"California Pacific Medical Center Foundation","award":["R37AG009901"],"award-info":[{"award-number":["R37AG009901"]}]},{"name":"California Pacific Medical Center Foundation","award":["R01AG018668"],"award-info":[{"award-number":["R01AG018668"]}]},{"name":"California Pacific Medical Center Foundation","award":["R01 AG029315"],"award-info":[{"award-number":["R01 AG029315"]}]},{"name":"California Pacific Medical Center Foundation","award":["T32AG00262"],"award-info":[{"award-number":["T32AG00262"]}]},{"name":"California Pacific Medical Center Foundation","award":["P30AG028747"],"award-info":[{"award-number":["P30AG028747"]}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["No. 58-1950-4-003"],"award-info":[{"award-number":["No. 58-1950-4-003"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sarcopenia is often conceptualized as a precursor to loss of mobility, but its effect on recovery of mobility after a hip fracture is unknown. We determined the prevalence of low muscle strength (weakness) after hip fracture using putative sarcopenia metrics (absolute grip strength, and grip strength normalized to body mass index, total body fat, arm lean mass, and weight) identified by the Sarcopenia Definitions and Outcomes Consortium (SDOC).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We examined two well-characterized hip fracture cohorts of community-dwelling older adults from the Baltimore Hip Studies (BHS). The prevalence of muscle weakness was assessed using the SDOC cut points compared to published definitions at 2 and 6 months postfracture. We assessed associations of 2-month weakness with 6-month walking speed &amp;lt;0.6 m\/s and calculated the sensitivity and specificity in predicting lack of meaningful change in walking speed (change &amp;lt; 0.1 m\/s) at 6 months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Two hundred and forty-six participants (192 women; 54 men) were included; mean (SD) age of 81 (8) for women and 78 (7) for men. At 2 months, 91% women and 78% men exhibited slow walking speed (&amp;lt; 0.6 m\/s). SDOC grip strength standardized by weight (&amp;lt;0.34 kg women, &amp;lt;0.45 kg men) was the most prevalent measure of weakness in men (74%) and women (79%) and provided high sensitivity in men (86%) and women (84%) predicting lack of meaningful change in walking speed at 6 months, although specificity was poor to moderate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>SDOC cut points for grip strength standardized to weight provided consistent indication of poor walking speed performance post-hip fracture.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glaa076","type":"journal-article","created":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T03:15:14Z","timestamp":1585883714000},"page":"1379-1385","source":"Crossref","is-referenced-by-count":13,"title":["Application of SDOC Cut Points for Low Muscle Strength for Recovery of Walking Speed After Hip Fracture"],"prefix":"10.1093","volume":"75","author":[{"given":"Denise L","family":"Orwig","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Magaziner","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger A","family":"Fielding","sequence":"additional","affiliation":[{"name":"Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen F","family":"Binder","sequence":"additional","affiliation":[{"name":"Department of Medicine, Washington University School of Medicine, St. Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4938-9478","authenticated-orcid":false,"given":"Peggy M","family":"Cawthon","sequence":"additional","affiliation":[{"name":"California Pacific Medical Research Institute, San Francisco"},{"name":"Department of Epidemiology and Biostatistics, University of California, San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalender","family":"Bhasin","sequence":"additional","affiliation":[{"name":"Research Program in Men\u2019s Health: Aging and Metabolism, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosaly","family":"Correa-de-Araujo","sequence":"additional","affiliation":[{"name":"Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Manini","sequence":"additional","affiliation":[{"name":"Department of Aging and Geriatric Research, University of Florida, Gainesville"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheena","family":"Patel","sequence":"additional","affiliation":[{"name":"California Pacific Medical Research Institute, San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5283-2082","authenticated-orcid":false,"given":"Michelle","family":"Shardell","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore"},{"name":"Longitudianl Studies Section, National Institute on Aging, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1030-7175","authenticated-orcid":false,"given":"Thomas G","family":"Travison","sequence":"additional","affiliation":[{"name":"Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts"},{"name":"Department of Medicine, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,4,3]]},"reference":[{"key":"2021040614363838700_CIT0001"},{"key":"2021040614363838700_CIT0002","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1007\/s00198-013-2375-9","article-title":"The impact of decreasing U.S. hip fracture rates on future hip fracture estimates","volume":"24","author":"Stevens","year":"2013","journal-title":"Osteoporos 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Current consensus definition: prevalence, etiology, and consequences. International Working Group on Sarcopenia","volume":"12","author":"Fielding","year":"2011","journal-title":"J Am Med Dir Assoc."},{"key":"2021040614363838700_CIT0016","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing."},{"issue":"1","key":"2021040614363838700_CIT0017","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2018","journal-title":"Age Ageing."},{"key":"2021040614363838700_CIT0018","article-title":"Identification of sarcopenia components that discriminate slow walking speed: a pooled data analysis from the Sarcopenia Definitions and Outcomes Consortium","author":"Manini","journal-title":"Currently under review"},{"key":"2021040614363838700_CIT0019","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/gerona\/glu023","article-title":"Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness","volume":"69","author":"Cawthon","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"2021040614363838700_CIT0020","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1093\/gerona\/glu011","article-title":"Grip strength cutpoints for the identification of clinically relevant weakness","volume":"69","author":"Alley","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"2021040614363838700_CIT0021","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1093\/gerona\/glu013","article-title":"An evidence-based comparison of operational criteria for the presence of sarcopenia","volume":"69","author":"Dam","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"2021040614363838700_CIT0022","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/gerona\/glu012","article-title":"Criteria for clinically relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: the foundation for the National Institutes of Health (FNIH) sarcopenia project","volume":"69","author":"McLean","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"2021040614363838700_CIT0023","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1001\/archinternmed.2011.15","article-title":"Delivery and outcomes of a yearlong home exercise program after hip fracture: a randomized controlled trial","volume":"171","author":"Orwig","year":"2011","journal-title":"Arch Intern Med."},{"key":"2021040614363838700_CIT0024","first-page":"162","article-title":"Examining differences in recovery outcomes between male and female hip fracture patients: design and baseline results of a prospective cohort study from the baltimore hip studies","volume":"7","author":"Orwig","year":"2018","journal-title":"J Frailty Aging."},{"issue":"4","key":"2021040614363838700_CIT0025","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1152\/jappl.1999.87.4.1513","article-title":"Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. 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