{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T08:11:42Z","timestamp":1772179902075,"version":"3.50.1"},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T00:00:00Z","timestamp":1593129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100008061","name":"Fundaci\u00f3n M\u00e9dica Mutua Madrile\u00f1a","doi-asserted-by":"crossref","award":["AP152932014"],"award-info":[{"award-number":["AP152932014"]}],"id":[{"id":"10.13039\/100008061","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sarcopenic patients may have an increased risk of poor outcomes after a hip fracture. The objective of this study was to determine whether sarcopenia and a set of biomarkers were potential predictors of 1-year-mortality in older patients after a hip fracture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>About 150 patients at least 80 years old were hospitalized for the surgical treatment of a hip fracture. The primary outcome measure was the death in the first year after the hip fracture. Sarcopenia was defined at baseline by having both low muscle mass (bioimpedance analysis) and handgrip and using the updated European Working Group on Sarcopenia in Older People (EWGSOP2) definition of probable sarcopenia. Janssen\u2019s (J) and Masan\u00e9s (M) cutoff points were used to define low muscle mass.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mortality 1 year after the hip fracture was 11.5%. In univariate analyses, baseline sarcopenia was not associated with mortality, using neither of the muscle mass cutoff points: 5.9% in sarcopenic (J) versus 12.4% in non-sarcopenic participants (p = .694) and 16% in sarcopenic (M) versus 9.6% in non-sarcopenic participants (p = .285). Probable sarcopenia (EWGSOP2) was not associated with mortality. Peripheral levels of IL-6 at baseline were significantly higher in the group of participants who died in the year after the hip fracture (17.14 \u00b1 16.74 vs 11.42 \u00b1 7.99 pg\/mL, p = .026). TNF-\u03b1 peripheral levels had a nonsignificant trend to be higher in participants who died. No other biomarker was associated with mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sarcopenia at baseline was not a predictor of 1-year mortality in older patients after a hip fracture. IL-6 was associated with a higher risk of mortality in these patients, regardless of sarcopenia status.<\/jats:p><\/jats:sec>","DOI":"10.1093\/gerona\/glaa154","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T22:33:49Z","timestamp":1593124429000},"page":"e130-e137","source":"Crossref","is-referenced-by-count":15,"title":["Peripheral IL-6 Levels but not Sarcopenia Are Predictive of 1-Year Mortality After Hip Fracture in Older Patients"],"prefix":"10.1093","volume":"75","author":[{"given":"Paloma","family":"Bermejo-Besc\u00f3s","sequence":"first","affiliation":[{"name":"Departamento de Farmacolog\u00eda, Farmacognosia y Bot\u00e1nica, Facultad de Farmacia, Universidad Complutense de Madrid (UCM), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sagrario","family":"Mart\u00edn-Arag\u00f3n","sequence":"additional","affiliation":[{"name":"Departamento de Farmacolog\u00eda, Farmacognosia y Bot\u00e1nica, Facultad de Farmacia, Universidad Complutense de Madrid (UCM), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso Jos\u00e9","family":"Cruz-Jentoft","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, IRYCIS, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Merello de Miguel","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, IRYCIS, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Nieves","family":"Vaquero-Pinto","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, IRYCIS, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"S\u00e1nchez-Castellano","sequence":"additional","affiliation":[{"name":"Hospital Universitario Ram\u00f3n y Cajal, IRYCIS, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"2020092513350124800_CIT0001","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1016\/S0140-6736(19)31138-9","article-title":"Sarcopenia","volume":"393","author":"Cruz-Jentoft","year":"2019","journal-title":"Lancet"},{"key":"2020092513350124800_CIT0002","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.jamda.2016.06.001","article-title":"Sarcopenia is recognized as an independent condition by an International Classification of Disease, tenth revision, Clinical Modification (ICD-10-CM) Code","volume":"17","author":"Cao","year":"2016","journal-title":"J Am Med Dir Assoc"},{"key":"2020092513350124800_CIT0003","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s41999-018-0079-6","article-title":"Sarcopenia and osteoporosis in older people: a systematic review and meta-analysis","volume":"9","author":"Nielsen","year":"2018","journal-title":"Eur Geriatr Med"},{"key":"2020092513350124800_CIT0004","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12877-018-0755-x","article-title":"Does sarcopenia predict change in mobility after hip fracture? A multicenter observational study with one-year follow-up","volume":"18","author":"Steihaug","year":"2018","journal-title":"BMC Geriatr"},{"key":"2020092513350124800_CIT0005","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s00198-017-3929-z","article-title":"The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation","volume":"28","author":"Landi","year":"2017","journal-title":"Osteoporos Int"},{"issue":"4","key":"2020092513350124800_CIT0006","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1093\/gerona\/gly138","article-title":"Biomarker signatures predicting 10-year all-cause and disease-specific mortality","volume":"74","author":"Lu","year":"2019","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2020092513350124800_CIT0007","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ebiom.2017.11.003","article-title":"Elevated neopterin levels predict early death in older hip-fracture patients","volume":"26","author":"Larsen","year":"2017","journal-title":"EBioMedicine"},{"key":"2020092513350124800_CIT0008","article-title":"Prevalence of sarcopenia and characteristics of sarcopenic subjects in patients over 80 years with hip fracture","author":"S\u00e1nchez Castellano","year":"2019","journal-title":"Nutr Hosp"},{"issue":"2","key":"2020092513350124800_CIT0009","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/jcsm.12508","article-title":"Biomarkers of sarcopenia in very old patients with hip fracture","volume":"11","author":"S\u00e1nchez-Castellano","year":"2020","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"5","key":"2020092513350124800_CIT0010","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1007\/s00198-019-04874-2","article-title":"Inflammatory cytokines IL-6 and TNF-\u03b1 in patients with hip fracture","volume":"30","author":"Saribal","year":"2019","journal-title":"Osteoporos Int"},{"key":"2020092513350124800_CIT0011","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.arr.2010.02.001","article-title":"Protein homeostasis and aging: the importance of exquisite quality control","volume":"10","author":"Koga","year":"2011","journal-title":"Ageing Res Rev"},{"key":"2020092513350124800_CIT0012","doi-asserted-by":"crossref","first-page":"227","DOI":"10.33549\/physiolres.930966","article-title":"Regulation of the ubiquitin proteasome system in mechanically injured human skeletal muscle","volume":"56","author":"Seiffert","year":"2007","journal-title":"Physiol Res"},{"key":"2020092513350124800_CIT0013","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.wneu.2015.10.010","article-title":"The role of serial oxidative stress levels in acute traumatic brain injury and as predictors of outcome","volume":"87","author":"Wang","year":"2016","journal-title":"World Neurosurg"},{"issue":"4\u20136","key":"2020092513350124800_CIT0014","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0940-2993(98)80037-7","article-title":"Plasma levels of glutathione, alpha-tocopherol and lipid peroxides in polytraumatized patients; evidence for a stimulating effect of TNF alpha on glutathione synthesis","volume":"50","author":"Kretzschmar","year":"1998","journal-title":"Exp Toxicol Pathol"},{"key":"2020092513350124800_CIT0015","doi-asserted-by":"crossref","first-page":"3591","DOI":"10.1182\/blood-2003-12-4103","article-title":"Antioxidative stress-associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress","volume":"104","author":"Dernbach","year":"2004","journal-title":"Blood"},{"key":"2020092513350124800_CIT0016","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12877-019-1109-z","article-title":"Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study","volume":"19","author":"Mao","year":"2019","journal-title":"BMC Geriatr"},{"key":"2020092513350124800_CIT0017","doi-asserted-by":"crossref","first-page":"e0203128","DOI":"10.1371\/journal.pone.0203128","article-title":"Association between early serum cholinesterase activity and 30-day mortality in sepsis-3 patients: a retrospective cohort study","volume":"13","author":"Peng","year":"2018","journal-title":"PLoS One"},{"key":"2020092513350124800_CIT0018","doi-asserted-by":"crossref","first-page":"274607","DOI":"10.1155\/2015\/274607","article-title":"Reduced serum butyrylcholinesterase activity indicates severe systemic inflammation in critically ill patients","volume":"2015","author":"Zivkovic","year":"2015","journal-title":"Mediators Inflamm"},{"key":"2020092513350124800_CIT0019","doi-asserted-by":"crossref","first-page":"5201652","DOI":"10.1155\/2018\/5201652","article-title":"Butyrylcholinesterase levels on admission predict severity and 12-month mortality in hospitalized AIDS patients","volume":"2018","author":"Xu","year":"2018","journal-title":"Mediators Inflamm"},{"key":"2020092513350124800_CIT0020","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.exger.2014.10.003","article-title":"Serum levels of C-terminal agrin fragment (CAF) are associated with sarcopenia in older hip fractured patients","volume":"60","author":"Marzetti","year":"2014","journal-title":"Exp Gerontol"},{"key":"2020092513350124800_CIT0021","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.exger.2016.03.012","article-title":"Serum levels of C-terminal agrin fragment (CAF) are associated with sarcopenia in older multimorbid community-dwellers: results from the ilSIRENTE study","volume":"79","author":"Landi","year":"2016","journal-title":"Exp Gerontol"},{"key":"2020092513350124800_CIT0022","first-page":"129","article-title":"Spanish language adaptation and validation of the Pfeiffer\u2019s questionnaire (SPMSQ) to detect cognitive deterioration in people over 65 years of age","volume":"117","author":"Mart\u00ednez de la Iglesia","year":"2001","journal-title":"Med Clin (Barc)"},{"key":"2020092513350124800_CIT0023","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1176\/ajp.139.9.1136","article-title":"The global deterioration scale for assessment of primary degenerative dementia","volume":"139","author":"Reisberg","year":"1982","journal-title":"Am J Psychiatry"},{"key":"2020092513350124800_CIT0024","first-page":"61","article-title":"Functional evaluation: the Barthel index","volume":"14","author":"Mahoney","year":"1965","journal-title":"Md State Med J"},{"key":"2020092513350124800_CIT0025","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/ptj\/64.1.35","article-title":"Clinical gait assessment in the neurologically impaired. Reliability and meaningfulness","volume":"64","author":"Holden","year":"1984","journal-title":"Phys Ther"},{"key":"2020092513350124800_CIT0026","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s12603-009-0214-7","article-title":"Validation of the mini nutritional assessment short-form (MNA-SF): a practical tool for identification of nutritional status","volume":"13","author":"Kaiser","year":"2009","journal-title":"J Nutr Health Aging"},{"key":"2020092513350124800_CIT0027","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"2020092513350124800_CIT0028","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/aje\/kwh058","article-title":"Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women","volume":"159","author":"Janssen","year":"2004","journal-title":"Am J Epidemiol"},{"key":"2020092513350124800_CIT0029","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s12603-011-0108-3","article-title":"Prevalence of sarcopenia in healthy community-dwelling elderly in an urban area of Barcelona (Spain)","volume":"16","author":"Masan\u00e9s","year":"2012","journal-title":"J Nutr Health Aging"},{"key":"2020092513350124800_CIT0030","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/ageing\/afz046","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"2020092513350124800_CIT0031","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.injury.2008.01.048","article-title":"Influence of optimised treatment of people with hip fracture on time to operation, length of hospital stay, reoperations and mortality within 1 year","volume":"39","author":"Hommel","year":"2008","journal-title":"Injury"},{"key":"2020092513350124800_CIT0032","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1111\/jgs.14237","article-title":"One-year mortality after hip fracture: development and validation of a prognostic index","volume":"64","author":"Cenzer","year":"2016","journal-title":"J Am Geriatr Soc"},{"key":"2020092513350124800_CIT0033","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.injury.2011.05.017","article-title":"Preoperative predictors for mortality following hip fracture surgery: a systematic review and meta-analysis","volume":"43","author":"Hu","year":"2012","journal-title":"Injury"},{"key":"2020092513350124800_CIT0034","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/2151458510378105","article-title":"The 1-year mortality of patients treated in a hip fracture program for elders","volume":"1","author":"Schnell","year":"2010","journal-title":"Geriatr Orthop Surg Rehabil"},{"key":"2020092513350124800_CIT0035","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.archger.2011.11.010","article-title":"Time to surgery and rehabilitation resources affect outcomes in orthogeriatric units","volume":"55","author":"Pioli","year":"2012","journal-title":"Arch Gerontol Geriatr"},{"key":"2020092513350124800_CIT0036","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.injury.2018.01.003","article-title":"Baseline and pre-operative 1-year mortality risk factors in a cohort of 509 hip fracture patients consecutively admitted to a co-managed orthogeriatric unit (FONDA Cohort)","volume":"49","author":"Men\u00e9ndez-Colino","year":"2018","journal-title":"Injury"},{"key":"2020092513350124800_CIT0037","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s11845-015-1271-z","article-title":"Predicting mortality following hip fracture: an analysis of comorbidities and complications","volume":"184","author":"Henderson","year":"2015","journal-title":"Ir J Med Sci"},{"key":"2020092513350124800_CIT0038","doi-asserted-by":"crossref","first-page":"pii:glz249","DOI":"10.1093\/gerona\/glz249","article-title":"Comparing EWGSOP2 and FNIH sarcopenia definitions: agreement and three-year survival prognostic value in older hospitalized adults. The GLISTEN Study","author":"Bianchi","year":"2019","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2020092513350124800_CIT0039","doi-asserted-by":"crossref","first-page":"e0169548","DOI":"10.1371\/journal.pone.0169548","article-title":"Health outcomes of sarcopenia: a systematic review and meta-analysis","volume":"12","author":"Beaudart","year":"2017","journal-title":"PLoS One"},{"issue":"6","key":"2020092513350124800_CIT0040","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1093\/gerona\/glx148","article-title":"FNIH-defined sarcopenia predicts adverse outcomes among community-dwelling older people in Taiwan: results from I-Lan longitudinal aging study","volume":"73","author":"Tang","year":"2018","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2020092513350124800_CIT0041","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.maturitas.2017.04.007","article-title":"Sarcopenia as a predictor of all-cause mortality among community-dwelling older people: a systematic review and meta-analysis","volume":"103","author":"Liu","year":"2017","journal-title":"Maturitas"},{"key":"2020092513350124800_CIT0042","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1007\/s00268-017-3999-2","article-title":"Radiologically determined sarcopenia predicts morbidity and mortality following abdominal surgery: a systematic review and meta-analysis","volume":"41","author":"Jones","year":"2017","journal-title":"World J Surg"},{"key":"2020092513350124800_CIT0043","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1007\/s00261-018-1870-z","article-title":"Sarcopenia predicts 90-day mortality in elderly patients undergoing emergency abdominal surgery","volume":"44","author":"Brandt","year":"2019","journal-title":"Abdom Radiol (NY)"},{"key":"2020092513350124800_CIT0044","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s12877-017-0569-2","article-title":"The impact of frailty and sarcopenia on postoperative outcomes in older patients undergoing gastrectomy surgery: a systematic review and meta-analysis","volume":"17","author":"Shen","year":"2017","journal-title":"BMC Geriatr"},{"key":"2020092513350124800_CIT0045","doi-asserted-by":"crossref","first-page":"W208","DOI":"10.2214\/AJR.16.17226","article-title":"CT of patients with hip fracture: muscle size and attenuation help predict mortality","volume":"208","author":"Boutin","year":"2017","journal-title":"AJR Am J Roentgenol"},{"key":"2020092513350124800_CIT0046","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s00774-019-00986-1","article-title":"Psoas cross-sectional area as a predictor of mortality and a diagnostic tool for sarcopenia in hip fracture patients","volume":"37","author":"Byun","year":"2019","journal-title":"J Bone Miner Metab"},{"key":"2020092513350124800_CIT0047","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.3346\/jkms.2018.33.e27","article-title":"Osteosarcopenia in patients with hip fracture is related with high mortality","volume":"33","author":"Yoo","year":"2018","journal-title":"J Korean Med Sci"},{"key":"2020092513350124800_CIT0048","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40001-017-0266-9","article-title":"A study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-\u03b1","volume":"22","author":"Bian","year":"2017","journal-title":"Eur J Med Res"},{"key":"2020092513350124800_CIT0049","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1007\/s00198-019-04874-2","article-title":"Inflammatory cytokines IL-6 and TNF-\u03b1 in patients with hip fracture","volume":"30","author":"Saribal","year":"2019","journal-title":"Osteoporos Int"},{"key":"2020092513350124800_CIT0050","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/gerona\/glt023","article-title":"Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults","volume":"69","author":"Varadhan","year":"2014","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2020092513350124800_CIT0051","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s11357-010-9165-5","article-title":"Systemic inflammation (interleukin 6) predicts all-cause mortality in men: results from a 9-year follow-up of the MEMO Study","volume":"33","author":"Baune","year":"2011","journal-title":"Age (Dordr)"},{"key":"2020092513350124800_CIT0052","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/gerona\/gly117","article-title":"A murine frailty index based on clinical and laboratory measurements: links between frailty and pro-inflammatory cytokines differ in a sex-specific manner","volume":"74","author":"Kane","year":"2019","journal-title":"J Gerontol A Biol Sci Med Sci"},{"issue":"7","key":"2020092513350124800_CIT0053","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.injury.2011.01.010","article-title":"Plasma concentrations of pro- and anti-inflammatory cytokines and outcome prediction in elderly hip fracture patients","volume":"42","author":"Sun","year":"2011","journal-title":"Injury"},{"issue":"9","key":"2020092513350124800_CIT0054","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1111\/j.1532-5415.2008.01851.x","article-title":"Time-course of cytokines during delirium in elderly patients with hip fractures","volume":"56","author":"Van Munster","year":"2008","journal-title":"J Am Geriatr Soc"}],"container-title":["The Journals of Gerontology: Series A"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biomedgerontology\/advance-article-pdf\/doi\/10.1093\/gerona\/glaa154\/33493472\/glaa154.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/biomedgerontology\/article-pdf\/75\/10\/e130\/33792855\/glaa154.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/biomedgerontology\/article-pdf\/75\/10\/e130\/33792855\/glaa154.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T11:25:55Z","timestamp":1667129155000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biomedgerontology\/article\/75\/10\/e130\/5862778"}},"subtitle":[],"editor":[{"given":"Anne","family":"Newman","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,6,26]]},"references-count":54,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,6,26]]},"published-print":{"date-parts":[[2020,9,25]]}},"URL":"https:\/\/doi.org\/10.1093\/gerona\/glaa154","relation":{},"ISSN":["1079-5006","1758-535X"],"issn-type":[{"value":"1079-5006","type":"print"},{"value":"1758-535X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,10]]},"published":{"date-parts":[[2020,6,26]]}}}