{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:07:30Z","timestamp":1762445250470,"version":"3.37.3"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,10,9]],"date-time":"2021-10-09T00:00:00Z","timestamp":1633737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>COVID-19 severely impacted older adults and long-term care facility (LTCF) residents. Our primary aim was to describe differences in clinical and epidemiological variables, in-hospital management, and outcomes between LTCF residents and community-dwelling older adults hospitalized with COVID-19. The secondary aim was to identify risk factors for mortality due to COVID-19 in hospitalized LTCF residents.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a cross-sectional analysis within a retrospective cohort of hospitalized patients \u226575 years with confirmed COVID-19 admitted to 160 Spanish hospitals. Differences between groups and factors associated with mortality among LTCF residents were assessed through comparisons and logistic regression analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 6 189 patients \u226575 years, 1 185 (19.1%) were LTCF residents and 4 548 (73.5%) were community-dwelling. LTCF residents were older (median: 87.4 vs 82.1 years), mostly female (61.6% vs 43.2%), had more severe functional dependence (47.0% vs 7.8%), more comorbidities (Charlson Comorbidity Index: 6 vs 5), had dementia more often (59.1% vs 14.4%), and had shorter duration of symptoms (median: 3 vs 6 days) than community-dwelling patients (all, p &amp;lt; .001). Mortality risk factors in LTCF residents were severe functional dependence (adjusted odds ratios [aOR]: 1.79; 95% confidence interval [CI]: 1.13\u20132.83; p = .012), dyspnea (1.66; 1.16\u20132.39; p = .004), SatO2 &amp;lt; 94% (1.73; 1.27\u20132.37; p = .001), temperature \u2265 37.8\u00b0C (1.62; 1.11\u20132.38; p = .013); qSOFA index \u2265 2 (1.62; 1.11\u20132.38; p = .013), bilateral infiltrates (1.98; 1.24\u20132.98; p &amp;lt; .001), and high C-reactive protein (1.005; 1.003\u20131.007; p &amp;lt; .001). In-hospital mortality was initially higher among LTCF residents (43.3% vs 39.7%), but lower after adjusting for sex, age, functional dependence, and comorbidities (aOR: 0.74, 95%CI: 0.62\u20130.87; p &amp;lt; .001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Basal functional status and COVID-19 severity are risk factors of mortality in LTCF residents. The lower adjusted mortality rate in LTCF residents may be explained by earlier identification, treatment, and hospitalization for COVID-19.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glab305","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T02:14:46Z","timestamp":1633918486000},"page":"e138-e147","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Features and Risk Factors for Mortality Among Long-term Care Facility Residents Hospitalized Due to COVID-19 in Spain"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6501-9867","authenticated-orcid":false,"given":"Jos\u00e9-Manuel","family":"Ramos-Rinc\u00f3n","sequence":"first","affiliation":[{"name":"Clinical Medicine Department, Miguel Hernandez University of Elche, Alicante, 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Department, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-del-Mar","family":"Garc\u00eda-Andreu","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Royo Villanova Hospital, Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan-Jos\u00e9","family":"Mancebo-Sevilla","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, M\u00e1laga Regional University Hospital- Biomedical Research Institute of M\u00e1laga (IBIMA), M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Jim\u00e9nez-Juan","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Virgen del Roc\u00edo University Hospital, Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Mat\u00eda-Sanz","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Royo Villanova Hospital, Zaragoza, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"L\u00f3pez-Quirantes","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, M\u00e1laga Regional University Hospital- Biomedical Research Institute of M\u00e1laga (IBIMA), M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Rubio-Rivas","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Bellvitge University Hospital- -IDIBELL, L\u2019Hospitalet de Llobregat (Barcelona), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Paredes-Ruiz","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, 12 Octubre University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candela","family":"Gonz\u00e1lez-San-Narciso","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Gregorio Mara\u00f1on University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roc\u00edo","family":"Gonz\u00e1lez-Vega","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Costa del Sol Hospital, Marbella (Malaga), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Sanz-Espinosa","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Rio Hortega University Hospital, Valladolid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almudena","family":"Hern\u00e1ndez-Mili\u00e1n","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Son Ll\u00e0tzer University Hospital, Palma de Mallorca, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amara","family":"Gonzalez-Noya","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Ourense University Hospital Complex, Ourense, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Gil-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, La Fe University Hospital, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramon","family":"Boixeda","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Matar\u00f3 Hospital, Matar\u00f3 (Barcelona), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9-Nicol\u00e1s","family":"Alcal\u00e1-Pedrajas","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Pozoblanco Hospital, Pozoblanco (Cordoba), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Palop-Cervera","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Sagunto University Hospital, Sagunto (Valencia), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Cort\u00e9s-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Alto Guadalquivir Hospital, And\u00fajar (Ja\u00e9n), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Esther","family":"Guisado-Espartero","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Infanta Margarita Hospital, Cabra (C\u00f3rdoba), Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Mella-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Ferrol University Hospital Complex, (Ferrol) A Coruna, 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