{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:41:58Z","timestamp":1789753318144,"version":"4.0.1"},"reference-count":57,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T00:00:00Z","timestamp":1647043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIHR Applied Research Collaboration Oxford and Thames Valley at Oxford Health NHS Foundation Trust","award":["PTC-RP-PG-0213-20002"],"award-info":[{"award-number":["PTC-RP-PG-0213-20002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Neurogenic claudication (NC) is a debilitating spinal condition affecting older adults\u2019 mobility and quality of life.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A randomized controlled trial of 438 participants evaluated the effectiveness of a physical and psychological group intervention (BOOST program) compared to physiotherapy assessment and tailored advice (best practice advice [BPA]) for older adults with NC. Participants were identified from spinal clinics (community and secondary care) and general practice records and randomized 2:1 to the BOOST program or BPA. The primary outcome was the Oswestry Disability Index (ODI) at 12 months. Data were also collected at 6 months. Other outcomes included ODI walking item, 6-minute walk test (6MWT), and falls. The primary analysis was intention-to-treat.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The average age of participants was 74.9 years (standard deviation [SD] 6.0) and 57% (246\/435) were female. There was no significant difference in ODI scores between treatment groups at 12 months (adjusted mean difference [MD]: \u22121.4 [95% confidence intervals (CI) \u22124.03, 1.17]), but, at 6 months, ODI scores favored the BOOST program (adjusted MD: \u22123.7 [95% CI \u22126.27, \u22121.06]). At 12 months, the BOOST program resulted in greater improvements in walking capacity (6MWT MD: 21.7m [95% CI 5.96, 37.38]) and ODI walking item (MD: \u22120.2 [95% CI \u22120.45, \u22120.01]) and reduced falls risk (odds ratio: 0.6 [95% CI 0.40, 0.98]) compared to BPA. No serious adverse events were related to either treatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The BOOST program substantially improved mobility for older adults with NC. Future iterations of the program will consider ways to improve long-term pain-related disability.<\/jats:p>\n                  <jats:p>Clinical Trials Registration Number: ISRCTN12698674<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glac063","type":"journal-article","created":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T22:10:07Z","timestamp":1647123007000},"page":"1654-1664","source":"Crossref","is-referenced-by-count":21,"title":["The Clinical Effectiveness of a Physiotherapy Delivered Physical and Psychological Group Intervention for Older Adults With Neurogenic Claudication: The BOOST Randomized Controlled Trial"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0638-0406","authenticated-orcid":false,"given":"Esther","family":"Williamson","sequence":"first","affiliation":[{"name":"Nuffield Department of Rheumatology, Orthopaedics and Musculoskeletal Sciences, University of Oxford , Oxford , UK"},{"name":"College of 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