{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:57:42Z","timestamp":1793051862203,"version":"4.5.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1R03AG067937"],"award-info":[{"award-number":["1R03AG067937"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["1K76AG074903"],"award-info":[{"award-number":["1K76AG074903"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30 AG044281"],"award-info":[{"award-number":["P30 AG044281"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007921","name":"University of Pittsburgh","doi-asserted-by":"publisher","award":["P30AG024827"],"award-info":[{"award-number":["P30AG024827"]}],"id":[{"id":"10.13039\/100007921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007154","name":"Wake Forest University","doi-asserted-by":"publisher","award":["UL1 0TR001420"],"award-info":[{"award-number":["UL1 0TR001420"]}],"id":[{"id":"10.13039\/100007154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007154","name":"Wake Forest University","doi-asserted-by":"publisher","award":["P30AG021332"],"award-info":[{"award-number":["P30AG021332"]}],"id":[{"id":"10.13039\/100007154","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Lower urinary tract symptoms (LUTS) and mobility limitations are bidirectionally associated among older adults, but the role of skeletal muscle remains unknown. We evaluated cross-sectional associations of muscle health and physical performance with LUTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data from 377 women and 264 men aged &amp;gt;70 years in the Study of Muscle, Mobility and Aging (SOMMA). LUTS and urinary bother were assessed using the LURN Symptom Index-10 (SI-10; higher\u2005=\u2005worse symptoms). Muscle mass and volume were assessed using D3-creatine dilution (D3Cr) and magnetic resonance imaging. Grip strength and peak leg power assessed upper\/lower extremity physical performance. 400-m walk, Short Physical Performance Battery (SPPB), and Four Square Step Test (FSST) assessed global physical performance. Mobility Assessment Tool-short form (MAT-sf) assessed self-reported mobility. We calculated Spearman correlation coefficients adjusted for age, body mass index, multimorbidity, and polypharmacy, chi-square tests, and Fisher\u2019s Z-test to compare correlations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among women, LURN SI-10 total scores were inversely correlated with FSST (rs\u2005=\u20050.11, p\u2005=\u2005.045), grip strength (rs\u2005=\u2005\u22120.15, p\u2005=\u2005.006), and MAT-sf (rs\u2005=\u2005\u22120.18, p\u2005=\u2005.001), but not other muscle and physical performance measures in multivariable models. LURN SI-10 was not associated with any of these measures among men. Forty-four percent of women in the lowest tertile of 400-m walk speed versus 24% in the highest tertile reported they were at least \u201csomewhat bothered\u201d by urinary symptoms (p\u2005&amp;lt;\u2005.001), whereas differences among men were not significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Balance and grip strength were associated with LUTS severity in older women but not men. Associations with other muscle and physical performance measures varied by LUTS subtype but remained strongest among women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/gerona\/glad218","type":"journal-article","created":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T16:47:19Z","timestamp":1694191639000},"source":"Crossref","is-referenced-by-count":14,"title":["Skeletal Muscle Health, Physical Performance, and Lower Urinary Tract Symptoms in Older Adults: The Study of Muscle, Mobility, and Aging"],"prefix":"10.1093","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4908-1924","authenticated-orcid":false,"given":"Scott R","family":"Bauer","sequence":"first","affiliation":[{"name":"Department of Medicine, University of California and the San Francisco Veterans Affairs Medical Center , San Francisco, California , USA"},{"name":"Department of Urology, University of California , San Francisco, California , 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3640-486X","authenticated-orcid":false,"given":"Russell T","family":"Hepple","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, College of Public Health and Health Professions, University of Florida , Gainesville, Florida , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Scherzer","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California and the San Francisco Veterans Affairs Medical Center , San Francisco, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Covinsky","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California and the San Francisco Veterans Affairs Medical Center , San Francisco, California , USA"},{"name":"Division of Geriatrics, Department of Medicine, University of California , San Francisco, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peggy M","family":"Cawthon","sequence":"additional","affiliation":[{"name":"San Francisco Coordinating Center, California Pacific Medical Center Research Institute , San Francisco, California , USA"},{"name":"Department of Epidemiology and Biostatistics, University of California , San Francisco, California , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"2024051011263849000_CIT0001","first-page":"352","article-title":"The prevalence of lower urinary tract symptoms (LUTS) in the USA, the UK and Sweden: results from the Epidemiology of LUTS (EpiLUTS) Study","volume-title":"BJU Int","author":"Coyne","year":"2009"},{"key":"2024051011263849000_CIT0002","first-page":"37","article-title":"The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee 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