{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:58:55Z","timestamp":1753876735018,"version":"3.41.2"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42375181","42307540"],"award-info":[{"award-number":["42375181","42307540"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wuhan Center for Disease Control and Prevention","award":["1602-250000196"],"award-info":[{"award-number":["1602-250000196"]}]},{"name":"Wuhan Municipal Health Commission","award":["WY19A01"],"award-info":[{"award-number":["WY19A01"]}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M722450"],"award-info":[{"award-number":["2022M722450"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2042022kf1029"],"award-info":[{"award-number":["2042022kf1029"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Physical functional limitations (PFLs) increase the vulnerability of adults, but their pathogenesis remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a nationwide longitudinal study on 62\u00a0749 records from 18\u00a0878 adults (aged \u226545) from 28 provinces in China. Risk of PFLs was assessed using a validated 9-item questionnaire. Exposure levels of air pollutants (PM10, PM2.5, and PM1) and greenness (normalized difference vegetation index, NDVI) were estimated using a satellite-based spatiotemporal model. We used the cumulative link mixed effects model to estimate the associations between short-term and long-term exposure to air pollutants, greenness, and risk of PFLs. We employed the interaction effect model to evaluate interactions between air pollutants and greenness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Participants were 60.9\u2005\u00b1\u20059.6 years, with an average follow-up of 5.87 (1.65) years. Exposure to air pollution was significantly associated with a higher risk of PFLs. For instance, the odds ratio (OR) associated with each 10 \u03bcg\/m3 higher in 6-month averaged PM10, PM2.5, and PM1 were 1.025 (95% CI: 1.015\u20131.035), 1.035 (95% CI: 1.018\u20131.054), and 1.029 (95% CI: 1.007\u20131.050), respectively. Conversely, exposure to greenness was associated with decreased risk of PFLs; the OR associated with each 1-unit higher in 1-year averaged NDVI was 0.724 (95% CI: 0.544\u20130.962). Furthermore, higher greenness levels were found to mitigate the adverse effects of 1-year, 6-month, 1-month averaged PM10, and 1-year averaged PM2.5 on the risk of PFLs.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Air pollution raises the risk of PFLs, whereas greenness could mitigate the adverse effects. Reducing air pollution and enhancing greenness could prevent physical functioning.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glae042","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T18:54:36Z","timestamp":1708368876000},"source":"Crossref","is-referenced-by-count":2,"title":["The Impact of Air Pollution on Physical Functioning Decline and the Benefits of Greenness: Evidence From a Nationwide Cohort Study"],"prefix":"10.1093","volume":"79","author":[{"given":"Ke","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"He","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Sciences, School of Public Health, University of Michigan , Ann Arbor, Michigan , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongyang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengnan","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahui","family":"Tong","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejian","family":"Kou","sequence":"additional","affiliation":[{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Dong Fureng Institute of Economic and Social Development, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feifei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public Health, Wuhan University , Wuhan , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0902-0115","authenticated-orcid":false,"given":"Hao","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Global Health, School of Public Health, Wuhan University , Wuhan , China"},{"name":"Global Health Institute, School of Public 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