{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:57:13Z","timestamp":1791910633246,"version":"4.3.4"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T00:00:00Z","timestamp":1713744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Contemporary data on the quantity and quality of medication use among older adults are lacking. This study examined recent trends in the number and appropriateness of prescription medication use among older adults in the United States.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data from the National Health and Nutrition Examination Survey (NHANES) between 2011 and March 2020 were used, and 6\u00a0336 adult participants aged 65 and older were included. We examined the number of prescription medication, prevalence of polypharmacy (\u22655 prescription drugs), use of potentially inappropriate medication (PIM), and use of recommended medications (angiotensin-converting enzyme inhibitor [ACEI]\/angiotensin receptor blockers [ARBs] plus beta-blockers among patients with heart failure and ACEI\/ARBs among patients with albuminuria).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There has been a slight increase in the prevalence of polypharmacy (39.3% in 2011\u20132012 to 43.8% in 2017\u20132020, p for trend\u2005=\u2005.32). Antihypertensive, antihyperlipidemic, antidiabetic medications, and antidepressants are the most commonly used medications. There was no substantial change in the use of PIM (17.0% to 14.7%). Less than 50% of older adults with heart failure received ACEI\/ARBs plus beta-blockers (44.3% in 2017\u20132020) and approximately 50% of patients with albuminuria received ACEI\/ARBs (54.0% in 2017\u20132020), with no improvement over the study period. Polypharmacy, older age, female, and lower socioeconomic status were generally associated with greater use of PIM but lower use of recommended medications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The medication burden remained high among older adults in the United States and the appropriate utilization of medications did not improve in the recent decade. Our results underscore the need for greater attentions and interventions to the quality of medication use among older adults.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glae108","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T05:55:06Z","timestamp":1713765306000},"source":"Crossref","is-referenced-by-count":15,"title":["Trends in Number and Appropriateness of Prescription Medication Utilization Among Community-Dwelling Older Adults in the United States: 2011\u20132020"],"prefix":"10.1093","volume":"79","author":[{"given":"Shaoxi","family":"Pan","sequence":"first","affiliation":[{"name":"School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University , Guiyang 561113 , China"},{"name":"China Center for Health Economic Research, Peking University , Beijing , 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