{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T15:10:11Z","timestamp":1789571411239,"version":"build-2803163510"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["MOST 111-2314-B-532-002"],"award-info":[{"award-number":["MOST 111-2314-B-532-002"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Taipei City Hospital, Taiwan","award":["TPCH-112-03"],"award-info":[{"award-number":["TPCH-112-03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Denture use may contribute to maintaining cognitive function by addressing the masticatory difficulties caused by tooth loss. However, reports on the association between tooth loss and cognitive impairment have been inconsistent. The impact of changes in tooth number and denture use on the development of cognitive impairment in older adults remains unclear. This study aimed to evaluate these impacts among community-dwelling older adults.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This 7-year longitudinal prospective cohort study included 64\u2005520 community-dwelling Taiwanese older adults aged \u226565 years without cognitive impairment at baseline. The primary outcome was cognitive impairment assessed using the Short Portable Mental Status Questionnaire.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Older adults with 10\u201319, 1\u20139, and 0 teeth, including natural teeth and dentures, had higher risks of developing cognitive impairment than those with \u226520 teeth, with adjusted odds ratios (ORs) of 1.40 (95% confidence intervals [CIs], 1.14\u20131.71), 1.85 (95% CI, 1.40\u20132.43), and 2.56 (95% CI, 1.74\u20133.76), respectively. Furthermore, among those with 10\u201319 teeth (OR, 0.71; 95% CI, 0.52\u20130.98) or 1\u20139 teeth (OR, 0.43, 95% CI, 0.27\u20130.68) at baseline, an increase of more than 1 level in tooth number during follow-up (eg, from 10\u201319 to \u2265 20 teeth and dentures through the acquisition of dental prosthetics such as dentures, bridges, or implants) was associated with a lower risk of developing cognitive impairment compared with those with a stable tooth number.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our findings suggest that prompt denture use and maintaining &amp;gt;20 teeth (including natural teeth and dentures) mitigate the risk of cognitive impairment associated with tooth loss among community-dwelling older adults.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/gerona\/glae248","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T04:31:29Z","timestamp":1732768289000},"source":"Crossref","is-referenced-by-count":13,"title":["Denture Use Mitigates the Cognitive Impact of Tooth Loss in Older Adults"],"prefix":"10.1093","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7478-0105","authenticated-orcid":false,"given":"Yi-Chang","family":"Chou","sequence":"first","affiliation":[{"name":"Department of Education and Research, Taipei City Hospital , Taipei ,","place":["Taiwan"]},{"name":"Department of Exercise and Health Sciences,\u00a0University of Taipei , Taipei ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7674-8280","authenticated-orcid":false,"given":"Shih-Han","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Education and Research, Taipei City Hospital , Taipei ,","place":["Taiwan"]},{"name":"Department of Health and Welfare,\u00a0University of Taipei , Taipei ,\u00a0","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0042-3141","authenticated-orcid":false,"given":"Feng-Shiang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Education and Research, Taipei City Hospital , Taipei ,","place":["Taiwan"]},{"name":"Department of Health and Welfare,\u00a0University of Taipei , Taipei ,\u00a0","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3604-3494","authenticated-orcid":false,"given":"Hsiao-Yun","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Education and Research, Taipei City Hospital , Taipei ,","place":["Taiwan"]},{"name":"Department of Health and Welfare,\u00a0University of Taipei , Taipei ,\u00a0","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"issue":"10033","key":"2024121210040028200_CIT0001","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1016\/S0140-6736(15)00516-4","article-title":"The World report on ageing and health: a policy framework for healthy ageing","volume":"387","author":"Beard","year":"2016","journal-title":"Lancet."},{"issue":"2","key":"2024121210040028200_CIT0002","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1016\/S2468-2667(21)00249-8","article-title":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019","volume":"7","author":"Nichols","year":"2022","journal-title":"Lancet Public Health"},{"issue":"4","key":"2024121210040028200_CIT0003","doi-asserted-by":"publisher","first-page":"e019908","DOI":"10.1136\/bmjopen-2017-019908","article-title":"Preventing emergency department (ED) visits and hospitalisations of older adults with cognitive impairment compared with the general senior population: what do we know about avoidable incidents? 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