{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:51:44Z","timestamp":1790668304052,"version":"4.1.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"National Institute of Aging (NIA) of the National Institutes of Health","award":["R01AG066562"],"award-info":[{"award-number":["R01AG066562"]}]},{"name":"National Institute of Aging (NIA) of the National Institutes of Health","award":["Prevention Center Shared Resource"],"award-info":[{"award-number":["Prevention Center Shared Resource"]}]},{"name":"National Institute of Aging (NIA) of the National Institutes of Health","award":["SCR026631"],"award-info":[{"award-number":["SCR026631"]}]},{"name":"Fred Hutch\/University of Washington\/Seattle Children\u2019s Cancer Consortium","award":["P30 CA015704"],"award-info":[{"award-number":["P30 CA015704"]}]},{"name":"NIH\/NCATS","award":["UM1 TR004399"],"award-info":[{"award-number":["UM1 TR004399"]}]},{"name":"NIH\/NCATS","award":["NIA K24AG082527"],"award-info":[{"award-number":["NIA K24AG082527"]}]},{"name":"NIH\/NCATS","award":["NIDDK P30 DK048520"],"award-info":[{"award-number":["NIDDK P30 DK048520"]}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["T32 AI150547"],"award-info":[{"award-number":["T32 AI150547"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NIH Public Access Policy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We compared two exercise intensities on lean and fat mass among older people with HIV (PWH). The High Intensity Exercise to Attenuate Limitations and Train Habits (HEALTH) randomized sedentary PWH \u226550\u2009years to 16\u2009weeks of high-intensity interval training (HIIT) or continuous moderate-intensity exercise (CME), both with resistance exercise. Body composition was measured using dual-energy x-ray absorptiometry (DXA) at baseline and week 16. The primary outcome was the percent change in body fat percentage (ratio of fat mass to total mass). Secondary outcomes included percent change in lean, fat, appendicular lean (ALM), and total mass. Linear regression models examined between- and within-group changes from baseline to week 16. Of the 95 participants with pre- and post-DXA scans, the median (interquartile range [IQR]) age was 58 [54-61] years, 14% female, 14% Black, and 14% Hispanic. Fat percentage decreased by \u22123.3% (95% confidence interval [CI]: \u22125.2, \u22121.6) in HIIT and \u22123.3% (95% CI: \u22125.3, \u22121.6) in CME. Fat mass decreased by \u22123.5% (95% CI: \u22125.9, \u22121.0) in HIIT and \u22123.8% (95% CI: \u22126.3, \u22121.3) in CME. Lean mass increased by 1.7% (95% CI: 0.7, 2.7) and ALM by 3.3% (95% CI: 1.3, 5.3) in HIIT and 1.2% (95% CI: 0.2, 2.2) and ALM by 2.6% (95% CI: 0.6, 4.6) in CME. Although both arms had significant improvements compared to baseline, no between-arm comparisons were statistically significant. Supervised HIIT or CME combined with resistance training for 16\u2009weeks is an effective strategy for improving body composition in previously sedentary older PWH.<\/jats:p>\n                  <jats:p>Clinicaltrials.gov: NCT04550676<\/jats:p>","DOI":"10.1093\/gerona\/glag113","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:51:20Z","timestamp":1777377080000},"source":"Crossref","is-referenced-by-count":3,"title":["The effects of high-intensity interval training versus continuous moderate-intensity exercise on body composition among older adults with HIV"],"prefix":"10.1093","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2318-3239","authenticated-orcid":false,"given":"Grace L","family":"Kulik","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Colorado-Anschutz Medical Campus , Aurora, Colorado,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitor H 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Colorado,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6618-1316","authenticated-orcid":false,"given":"Debashis","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Biostatistics & Informatics, University of Colorado-Anschutz Medical Campus , Aurora, Colorado,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison R","family":"Webel","sequence":"additional","affiliation":[{"name":"School of Nursing, University of Washington , Seattle, Washington,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0808-6729","authenticated-orcid":false,"given":"Kristine M","family":"Erlandson","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Colorado-Anschutz Medical Campus , Aurora, Colorado,","place":["United 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