{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:00:32Z","timestamp":1790236832812,"version":"4.1.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P30AG066614"],"award-info":[{"award-number":["P30AG066614"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigates whether life-course and socioeconomic exposures are similarly associated with accelerated biological aging across racial and ethnic groups and whether accelerated biological aging predicts health outcomes equivalently across groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data came from the Health and Retirement Study (2016-2022). Accelerated biological age was derived from 22 blood-based biomarkers from the 2016 Venous Blood Study. We used linear regression models with interactions between race\/ethnicity and life-course exposures (childhood adversity and adult\/midlife socioeconomic status (SES)) to assess group differences in accelerated aging. We used linear, ordered logistic, and logistic regression models with interactions between accelerated biological age and race\/ethnicity to assess group differences in health outcomes. We examined differences by foreign-born status among Hispanic adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Associations between life-course exposures, accelerated biological aging, and health varied by race\/ethnicity. Compared to non-Hispanic White adults, childhood health and adversity were not associated with accelerated biological aging for non-Hispanic Black and Hispanic adults, and among these groups, higher midlife SES did not decelerate biological aging. The association between accelerated biological age and health outcomes varied by race\/ethnicity; accelerated biological age was less predictive among non-Hispanic Black and Hispanic adults. Among Hispanic adults, increased biological age was more strongly linked to multimorbidity among foreign-born individuals than U.S.-born individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The processes linking life-course conditions to biological aging and biological aging to later-life health do not translate uniformly across racial\/ethnic groups. Future research should explore the sources of heterogeneity in life-course exposures and the mechanisms by which biological age translates into health outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/gerona\/glag207","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T14:12:34Z","timestamp":1787926354000},"source":"Crossref","is-referenced-by-count":1,"title":["Unequal embodiment: racial and ethnic heterogeneity in the predictors and age-related health outcomes associated with accelerated biological aging"],"prefix":"10.1093","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2146-162X","authenticated-orcid":false,"given":"Mariela","family":"Villalba Madrid","sequence":"first","affiliation":[{"name":"Department of Human Development and Family Sciences, The University of Texas at Austin , Austin, Texas,","place":["United 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